Jindong Wang

Shanghai Institute of Technical Physics

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Xuefeng Guo

Peking University

Lidong Li

University of Science and Technology Beijing

Maosheng Yao

State Key Joint Laboratory of Environment Simulation and Pollution Control

Fangxia Shen

Beihang University

Zhenxing Wang

Dezhou University

Huihao Li

Nanning Normal University

Zhenhua Ye

Shanghai Institute of Technical Physics

Gen He

Guangzhou Medical University

Jinwen Qin

Beijing Institute of Technology

Nongyi Cheng

University of Massachusetts Amherst

Cooperative Institutions

Chinese Academy of Sciences

Peking University

Shanghai Institute of Technical Physics

University of Chinese Academy of Sciences

Beijing National Laboratory for Molecular Sciences

Tsinghua University

Zhejiang University

Chongqing University

State Key Joint Laboratory of Environment Simulation and Pollution Control

State Key Laboratory for Structural Chemistry of Unstable and Stable Species

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Integrating Silicon Nanowire Field Effect Transistor, Microfluidics and Air Sampling Techniques For Real-Time Monitoring Biological Aerosols

Environmental Science & Technology (2011)

Fangxia Shen Miaomiao Tan Zhenxing Wang Maosheng Yao Zhenqiang Xu

Numerous threats from biological aerosol exposures, such as those from H1N1 influenza, SARS, bird flu, and bioterrorism activities necessitate the development of a real-time bioaerosol sensing system, which however is a long-standing challenge in the field. Here, we developed a real-time monitoring system for airborne influenza H3N2 viruses by integrating electronically addressable silicon nanowire (SiNW) sensor devices, microfluidics and bioaerosol-to-hydrosol air sampling techniques. When airborne influenza H3N2 virus samples were collected and delivered to antibody-modified SiNW devices, discrete nanowire conductance changes were observed within seconds. In contrast, the conductance levels remained relatively unchanged when indoor air or clean air samples were delivered. A 10-fold increase in virus concentration was found to give rise to about 20-30% increase in the sensor response. The selectivity of the sensing device was successfully demonstrated using H1N1 viruses and house dust allergens. From the simulated aerosol release to the detection, we observed a time scale of 1-2 min. Quantitative polymerase chain reaction (qPCR) tests revealed that higher virus concentrations in the air samples generally corresponded to higher conductance levels in the SiNW devices. In addition, the display of detection data on remote platforms such as cell phone and computer was also successfully demonstrated with a wireless module. The work here is expected to lead to innovative methods for biological aerosol monitoring, and further improvements in each of the integrated elements could extend the system to real world applications.

Bioaerosol

Silicon nanowires

Indoor bioaerosol

10.1021/es1043547

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Citations (91)

Design of novel deformable mirror with large displacement

Concurrency and Computation Practice and Experience (2023)

Jinchao Li Yuxuan Tian Jindong Wang Jinling Yang Yinfang Zhu

Summary A stabilized zoom system with deformable mirrors (DMs) was designed for continuous optical zoom. In order to adjust the focal length and expand the field angle, the characteristic surface shapes of the DMs composed of the low‐order and high‐order Zernike polynomials were provided. The maximum peak‐to‐valley (PV) value at the center of the surface shape is 80 μm. This work presents a piezoelectrically‐actuated deformable mirror (PADM) with large displacement for a stabilized zoom system. The COMSOL simulation was conducted to obtain the desired design by matching and optimizing structural parameters. The maximum displacement of PADM was more than 80 μm. The fitting results by the steepest descent algorithm (SD) showed that the RMS values of the residual surface shapes were 1 of 7 to 1 of 4 of their PV values, and the PV values of the residual surface shapes were less than 1 of 10 of the PV values of the target surface shapes.

Deformable Mirror

10.1002/cpe.7984

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Citations (1)

Design of infrared metasurface splitter arrays

Optics and Precision Engineering (2021)

Jindong Wang Wen-cheng YE Wei-ting ZHANG Ai-liang CUI Qing-jun LIAO

Splitter

Beam splitter

10.37188/ope.20212904.0674

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Citations (0)

Point Decoration of Silicon Nanowires: An Approach Toward Single‐Molecule Electrical Detection

Angewandte Chemie International Edition (2014)

Jindong Wang Fangxia Shen Zhenxing Wang Gen He Jinwen Qin

Abstract Probing interactions of biological systems at the molecular level is of great importance to fundamental biology, diagnosis, and drug discovery. A rational bioassay design of lithographically integrating individual point scattering sites into electrical circuits is capable of realizing real‐time, label‐free biodetection of influenza H1N1 viruses with single‐molecule sensitivity and high selectivity by using silicon nanowires as local reporters in combination with microfluidics. This nanocircuit‐based architecture is complementary to more conventional optical techniques, but has the advantages of no bleaching problems and no fluorescent labeling. These advantages offer a promising platform for exploring dynamics of stochastic processes in biological systems and gaining information from genomics to proteomics to improve accurate molecular and even point‐of‐care clinical diagnosis.

Silicon nanowires

Molecular binding

10.1002/anie.201309438

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Citations (43)

Systematic prediction method for flip-chip bonding connectivity of ultra-large array infrared detector

Optics Express (2024)

Huihao Li Jindong Wang Yan Chen Qingjun Liao Changhong Sun

The flip-chip bonding technique utilized in ultra-large array infrared detectors has a substantial impact on connectivity rates. The electrical connectivity of the flip-chip bonding process exhibits randomness due to the difficulties in the surface control of large-scale devices. This restriction hinders the development of ultra-large array devices. In this work, the surface shape matching calculation is performed based on the surface shape distributions measured from infrared detector chips and readout circuits. The multi combinations and multi rotation angles are employed to calculate the distribution of combined surface distances, and the combined PV (peak-to-valley) value is applied to describe the severity of surface mismatch. Test devices with combined PV values ranging from 7.460 µm to 4.265 µm are prepared and tested, and the connectivity rate achieves an improvement from 74.57% to 99.75% between mismatched devices and matching devices. The electrical test results of test devices indicate that disconnections tend to cluster in areas where surface distance is over 5 µm, which is determined by extracting and analyzing the surface distance correlated to electrical test results. A standard based on the combined PV value is established to select matching combinations and ensure a high connectivity rate of 99% or 97% for infrared detectors, while the connectivity rates of randomly selected devices are no higher than 91%. This work presents a systematic method to predict and improve the connectivity rate of flip-chip bonding process for ultra-large array infrared detector.

10.1364/oe.514814

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Revealing Interface‐Assisted Charge‐Transfer Mechanisms by Using Silicon Nanowires as Local Probes

Angewandte Chemie International Edition (2013)

Jindong Wang Zhenxing Wang Qiaochu Li Lin Gan Xinjun Xu

A semiconductor/environment interface has been formed in which suspended silicon nanowires (SiNWs) are in direct contact with photoactive TiO2 quantum dots. The photoactivity of TiO2 competes with the intrinsic photoresponses of p-type silicon nanowires. Rational control of the competitive mechanism realizes remarkable mirror-imaging photo-switching and superior rectifying effects in a single SiNW-based device. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Interface (matter)

Silicon nanowires

10.1002/anie.201209816

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Citations (9)

Interface‐Engineered Bistable [2]Rotaxane‐Graphene Hybrids with Logic Capabilities

Advanced Materials (2013)

Chuancheng Jia Hao Li Jiaolong Jiang Jindong Wang Hongliang Chen

The use of high-quality graphene as a local probe in combination with photo excitation helps to establish a deep mechanistic understanding of charge generation/quenching processes under lying the graphene/environment interface. By combining a non-destructive bottom-up assembly technique with sensitive graphene-based transistors, a bistable [2]rotaxane-graphene hybrid device, which exhibits a symmetric mirror-image photoswitching effect with logic capabilities, is produced. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Bistability

Rotaxane

Interface (matter)

10.1002/adma.201302393

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Citations (55)

Liquefaction of kraft lignin over the composite catalyst HTaMoO6 and Rh/C in dioxane-water system

Fuel Processing Technology (2018)

Lele Jin Wenzhi Li Qiying Liu Jindong Wang Yuanshuai Zhu

Depolymerization

Fraction (chemistry)

10.1016/j.fuproc.2018.05.014