Systemic Epstein-Barr virus (EBV)-positive T-cell lymphoproliferative disease of childhood is a rare disease and has a very fulminant clinical course with high mortality. A 21-month-old female patient was referred to our hospital with a 1 week history of fever and was subsequently diagnosed with systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease of childhood. After starting treatment with dexamethasone, she showed early defervescence and improvement of laboratory parameters, and has remained disease-free after stopping steroid treatment, although longer follow-up is necessary. Our report underscores the possibility that this disease entity may be heterogenous in terms of prognosis.
Primary breast lymphoma is an extremely rare disease. Primary breast mucosa-associated lymphoid tissue (MALT) lymphoma is even rarer, and bilateral involvement is exceptional. We report on the F-FDG PET/CT findings in a patient with primary bilateral breast MALT lymphoma. F-FDG PET/CT showed hypermetabolic masses in both breasts. The patient was confirmed with bilateral primary breast MALT lymphoma after total mastectomy. Despite its rarity, primary breast MALT lymphoma should be considered in patients with hypermetabolic masses in the breast. If primary breast MALT lymphoma is suspected, F-FDG PET/CT is a useful tool for initial staging in patients.
Hereditary neuropathy with liability to pressure palsy (HNPP) makes nerves increasingly susceptible to mechanical pressure at entrapment sites. Neuralgic amyotrophy (NA) can cause sudden regional weakness following events to which the patient is immunologically predisposed, such as vaccination. However, NA related to human papilloma virus (HPV) vaccination is seldom reported. We describe the case of a child with NA as the cause of a dropped shoulder following the administration of the HPV vaccine. Underlying asymptomatic HNPP was confirmed in this patient based on the electrodiagnostic findings and genetic analysis. We speculate that HPV vaccination elicited an immune-mediated inflammatory response, resulting in NA. Our patient with pre-existing HNPP might be vulnerable to the occurrence of an immune-mediated NA, which caused the dropped shoulder.
목적 : 일본의 원격의료현황을 살펴보고, 이에 대한 지역사회작업치료의 역할에 대해 논한다. 연구방법 : 본 연구에서는 원격진료현황에 대한 자료를 수집하고 분석하였다. 원격진료에 대한 정의와 형태에 대해 조 사하였고, 일본에서 원격진료가 등장하게 된 배경에 대해 분석하였다. 이를 통해 지역사회 작업치료의 역할에 대해 논하였다. 결과 : 일본의 저출산·고령화로 인한 의료비의 증가로 보다 효율적인 의료서비스의 제공형태로 원격진료가 등장하였다. 또한 의사수 부족과 도시와 농촌간의 진료편차 및 진료기기와 통신수단의 발달로 인해 등장하였다. 한국의 경우 일본의 이러한 추세를 따라가고 있으며, 이에 따라 원격의료에 대한 수요가 있다. 결론 : 원격진료와 관련하여 지역사회중심재활에서 작업치료는 보건의료전문가로써 환자에게 작업치료를 수행할 수 있을 것으로 예상되는 바 이에 대한 교육시스템 개편이 필요하다.
Accurate and early detection of vancomycin-resistant enterococci (VRE) is critical for controlling nosocomial infection. In this study, we evaluated the usefulness of a selective chromogenic agar medium and of multiplex PCR for detection of VRE, and both these techniques were compared with the conventional culture method for VRE detection.We performed the following 3 methods for detecting VRE infection in stool specimens: the routine culture method, culturing in selective chromogenic agar medium (chromID VRE, bioMérieux, France), and multiplex PCR using the Seeplex® VRE ACE Detection kit (Seegene Inc., Korea) with additional PCR for vanC genes.We isolated 109 VRE strains from 100 stool specimens by the routine culture method. In chromID VRE, all the isolates showed purple colonies, including Enterococcus gallinarum and E. raffinosus, which were later identified using the Vitek card. All VRE isolates were identified by the multiplex PCR method; 100 were vanA-positive E. faecium, 8 were vanA- and vanC-1-positive E. gallinarum, and 1 was vanA-positive E. raffinosus.For VRE surveillance, culturing the isolates in chromID VRE after broth enrichment appears to be an accurate, rapid, and easy method for routine screening test. Multiplex PCR is relatively expensive and needs skilled techniques for detecting VRE, but it can be an auxiliary tool for rapid detection of genotype during a VRE outbreak.
A marker-assisted selection (MAS) breeding program was used to improve the plant regenerability of indica rice. A significant quantitative trait loci (QTL) that is associated with the capacity for green plant regeneration in the anther culture of rice was mapped on chromosome 10 using recombinant inbred (RI) population from Milyang 23/Gihobyeo. The marker that was chosen to follow the QTL region was used in MAS. This marker co-segregated with the regeneration ability in F2 individuals that were derived from MGRI 079/IR 36. In order to clarify the relationship between this marker and plant regenerability, the backcross population was screened with a RFLP marker. The capacity of plant regeneration of the backcross population was clearly distinguished by the marker genotype. The development of near isogenic line (NILs) with high regenerability through MAS will save time, labor, and cost in indica rice breeding.
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