Ming Xu

Union Hospital

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J.R. Figueiredo

Universidade Estadual do Ceará

A.B.G. Duarte

Universidade Estadual do Ceará

Marcelo Picinin Bernuci

Centro Universitário Cesumar

C.C. Campello

Universidade Estadual do Ceará

Lu Zhang

Wuhan University

Teresa K. Woodruff

Northwestern University

Shuyue Xiang

BOE Technology Group (China)

Yang Yu

Liaoning University of Traditional Chinese Medicine

Yue Zhang

Second Affiliated Hospital of Dalian Medical University

Beiyuan Fan

BOE Technology Group (China)

Cooperative Institutions

Universidade Estadual do Ceará

Shanghai Jiao Tong University

Universidade Federal do Ceará

Huazhong University of Science and Technology

Chinese Academy of Sciences

Chinese Academy of Medical Sciences & Peking Union Medical College

Shandong Tumor Hospital

Shandong First Medical University

Nanjing Medical University

Shanghai Children's Medical Center

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Is the mouse follicle culture a good model for the goat with respect to the development of preantral follicles in vitro?

Domestic Animal Endocrinology (2014)

Rebeca Magalhães Pedrosa Rocha Anelise Maria Costa Vasconcelos Alves Laritza Ferreira de Lima A.B.G. Duarte Roberta Nogueira Chaves

10.1016/j.domaniend.2014.04.005

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Citations (9)

Retrospective Analysis of Childhood Hepatoblastoma in a Single Centre in China

Clinical Oncology (2019)

T.Y. Wang Yali Han Yijin Gao Ming Xu Song Gu

Hepatoblastoma

Univariate analysis

10.1016/j.clon.2019.03.044

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Citations (18)

6538 POSTER Comparison of the Different Planning Targets Defined Basing on Three-dimensional CT and Four-dimensional CT Images for Liver Cancer

European Journal of Cancer (2011)

F.X. Li Jonathan Li Jinchun Xing Tao Fan Ming Xu

Liver Cancer

10.1016/s0959-8049(11)71849-4

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Animal age, weight and estrus cycle stage impact the quality of in vitro grown follicles

Human Reproduction (2011)

Jennifer Hirshfeld‐Cytron Francesca E. Duncan Ming Xu Jennifer K. Jozefik Lonnie D. Shea

Ovarian tissue cryopreservation is an emerging fertility preservation option, and culturing follicles isolated from this tissue to obtain mature gametes may ultimately be the best solution for patients for whom transplantation is contraindicated. It is unclear, however, how patient-specific variables (including age, weight and menstrual cycle stage) impact follicle growth and quality during three-dimensional culture.We used a mouse model to systematically determine how these variables impact in vitro follicle growth. We characterized metabolic and hormonal profiles of mice at specific ages, weights and cycle stages and secondary follicles from these cohorts were isolated and cultured. We then assessed follicle survival, growth and function, as well as meiotic competence and spindle morphology of the resulting oocytes.We found that older mice and mice with increased body weight had higher serum cholesterol, abnormal glucose tolerance and lower levels of circulating Anti-Müllerian hormone compared with younger and leaner controls. Secondary follicles isolated from different cohorts and grown in vitro had indistinguishable growth trajectories. However, the follicles isolated from older and heavier mice and those in diestrus had altered hormone profiles. These follicles contained oocytes with reduced meiotic competence and produced oocytes with greater spindle defects.These results suggest that the original physical environment of the follicle within the ovary can impact its function when isolated and cultured. These findings are valuable as we begin to use in vitro follicle growth technology for a heterogeneous fertility preservation patient population.

Anti-Müllerian hormone

10.1093/humrep/der183

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Citations (41)

Pseudomonas aeruginosa targeting cascade photodynamic nanoassemblies for efficient antibacterial and anti-inflammatory therapy

Nano Today (2023)

Changrong Wang Yifei Lin Jinghua Huang Huijuan Song Ye Zhang

10.1016/j.nantod.2023.101892

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Citations (17)

Comparison of vonoprazan-based with rabeprazole-based dual therapy for treatment-naive patients of Helicobacter pylori infection: a prospective, multi-center, randomized controlled study

Journal of Gastroenterology (2023)

Yingying Han Lin Zhou Yunlian Hu Xiangwu Ding Hui Long

Rabeprazole

Regimen

10.1007/s00535-023-02042-2

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Citations (13)

Association between thyroid hormone sensitivity and carotid plaque risk: a health examination cohort-based study

Frontiers in Endocrinology (2024)

Rui Gong Shi Wang Hong Ding Lixia Yu Ming Xu

The involvement of thyroid hormone in cardiovascular disease remains debated. The aim of our research was to ascertain whether thyroid hormone sensitivity indices are related to carotid plaque (CAP) risk in the general population.

10.3389/fendo.2024.1472752

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Urine Liquid Biopsies via Highly Integrated Digital PCR System for Accurate Detection of Bladder Cancer (Adv. Therap. 10/2024)

Advanced Therapeutics (2024)

Yue Zhang Ming Xu Zhihong Wu Fan Yang Lu Zhang

Liquid biopsy

10.1002/adtp.202470020

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EP-1423: Variation of cardiac volume based on repeated enhanced 4DCT during radiotherapy in esophageal cancer

Radiotherapy and Oncology (2018)

X. Wang J.Z. Wang J.B. Li Y.J. Zhang F.X. Li

S774ESTRO 37presented radiation induced liver disease RILD or toxic death.One patient had grade 3 gastric duodenal ulcers. ConclusionOur results indicate that SBRT is efficient and well tolerated for inoperable HCC.However, prospective randomized studies are warranted to confirm the place of SBRT in the treatment of HCC.

Variation (astronomy)

10.1016/s0167-8140(18)31732-8

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Urine Liquid Biopsies via Highly Integrated Digital PCR System for Accurate Detection of Bladder Cancer

Advanced Therapeutics (2024)

Yue Zhang Ming Xu Zhihong Wu Fan Yang Lu Zhang

Abstract Bladder cancer (BC) is a prevalent urological tumor with high recurrence rates, requiring long‐term monitoring. Although cystoscopy is the primary diagnostic method, its invasiveness and cost hinder routine screening and follow‐up. This study aimed to develop a novel diagnostic tool utilizing newly developed on‐chip heating dPCR platform, which features integrated and rapid temperature control capabilities, for non‐invasive BC detection. The dPCR platform is improved by integrating a multi‐color detection system, enabling precise quantification of mutant allelic fraction (MAF) of TERT promoter mutations with a limit of detection (LOD) of 0.29%. Diagnostic performance is enhanced by integrating the NRN1 methylation biomarker and employing machine learning to optimize biomarker weighting. Testing the model on urine samples from controls ( n = 35) and BC patients ( n = 41) yielded a sensitivity of 0.92, specificity of 0.94, and an AUC of 0.98, surpassing conventional cytology in sensitivity while maintaining comparable specificity. Furthermore, the model effectively differentiated between normal controls and different stages, achieving accuracies of 0.92, 0.71, and 0.79 for NC, stage I, and stage II+ respectively. These findings suggest the proposed dPCR assays could serve as a sensitive and non‐invasive approach for BC detection in clinical practice.

Cancer Detection

Liquid biopsy

10.1002/adtp.202400191

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