This paper analyzed comparatively the content and nature of rationality and inspiration during technology innovation,discussed the integration trend of rationality and inspiration,and researched integration characterization of rationality and inspiration from four aspects such as creative,dynamic,behavioral,and utilitarian,revealed rationality's specification and guidance mechanism to inspiration.
Background and objective Retreatment pulmonary tuberculosis (PTB) still accounts for a large proportion of tuberculosis, and the treatment outcome is unfavorable. The recurrence of retreatment PTB based on long-term follow-up has not been well demonstrated. This study aimed to evaluate effect of a modified regimen on drug-sensitive retreated pulmonary tuberculosis. Methods This multicenter cohort study was conducted in 29 hospitals from 23 regions of China from July 1, 2009, to December 31, 2020. Patients were divided into two treatment regimen groups including experimental group [modified regimen (4H-Rt2-E-Z-S(Lfx)/4H-Rt2-E)]and control group [standard regimen (2H-R-E-Z-S/6H-R-E or 3H-R-E-Z/6H-R-E)]. The patients enrolled were followed up of 56 months after successful treatment. We compared the treatment success rate, treatment failure rate, adverse reaction rate, and recurrence rate between two regimens. Multivariate Cox regression model was used to identify the potential risk factors for recurrence after successful treatment with proportional hazards assumptions tested for all variables. Results A total of 381 patients with retreatment PTB were enrolled, including 244 (64.0%) in the experimental group and 137 (36.0%) in the control group. Overall, the treatment success rate was significant higher in the experimental group than control group (84.0 vs. 74.5%, P = 0.024); no difference was observed in adverse reactions between the two groups (25.8 vs. 21.2%, P > 0.05). A total of 307 patients completed the 56 months of follow-up, including 205 with the modified regimen and 102 with the standard regimen. Among these, 10 cases (3.3%) relapsed, including 3 in the experimental group and 7 in the control group (1.5% vs 6.9%, P = 0.035). Reduced risks of recurrence were observed in patients treated with the modified regimen compared with the standard regimen, and the adjusted hazard ratio was 0.19 (0.04–0.77). Conclusion The modified retreatment regimen had more favorable treatment effects, including higher treatment success rate and lower recurrence rate in patients with retreated drug-sensitive PTB.
The balance condition of dynamical system and the meaning of balance condition of attractor were discussed from the views of physics and mathematics.The motive character attractor and how to form dissipative structure system of attractor were analysed.This revealed that we should warn crisis in national economy circulation,so that economy can develop steadily.
The relative independence between technology supply system and technology demand system hinders technological diffusion and upgrading.This paper analyzes the development of the two systems,discusses the docking difficulties of technology supply system and technology demand system from the macro and micro levels,and proposes docking mechanism of the two systems from the four aspects of docking planning,docking path,docking model and docking base.
The paper discussed methods for evaluating the intelligence of intelligent systems by means of computational semiotics concepts. Instead of looking at the system as a black box and testing its behavior, the process described in this paper focus on architectural details of structures, organizations, processes and algorithms used in the construction of the intelligent system, evaluating the impact of using these elements in the overall intelligent behavior exhibited by the system. It proposes then an "insider" type of metrics that, coupled to "outsider" metrics, we hope will be important for the determination of general metrics of intelligence in intelligent systems.
Deep Science is an innovative intelligent digital platform for international researcher. Combining preprint hosting and open peer review with intelligence, Deep Science aims to be the leading publishing venue for scholarly research worldwide.
The connotation of development pole of technology (DPT) indicates technology parks, science cities, technologies and the like, the paper considered the innovative circumstance is condition of DPT, and put forward the stage selected of DPT for developing countries. Finally, the paper advanced the economic policy of DPT for country development, that is, constructing pole of technology would be promote technological capacity building.
This paper analyzes the transition of the subject of technology innovation from the people-entrepreneurs-companies-organizations-people,and takes the 1960 technology innovation in our country for example to discuss the public subject of technology innovation.We consider the main form conditions of technological innovation of the public subject of technology innovation is individual innovation,the golden age,innovation environment,innovation mechanisms,science literacy.Finally,the paper presents policies and measures for strengthening the dominant position of the public subject of technology innovation.
Advanced manufacturing technology promotes perfect of the aviation industry collaborative digital manufacturing system,propels aviation manufacturing collaboration by grid service,operates interoperability each other across heterogeneous networks,speeds the development of integration technology with digital design,manufacturing,management,builds common and platform-independent services facilities based on a variety of heterogeneous platforms to assure information and services unimpeded flow between computers.Content distribution,service distribution,electronic services,real-time enterprise computing,distributed computing,Web services of grid services will drive application and development of aviation advanced manufacturing technology.