Chemically bonded aluminum phosphate coating modified with Al2O3-MWCNTs was prepared for anti-corrosion in high-temperature marine environment. a-Al2O3 was successfully and conveniently coupled to the multi-walled carbon nanotubes by surface modification. Then the hybrid materials mixed with coating materials were applied on heat-resistant steel using high-pressure airless spraying. SEM, XRD, FT-IR spectrum, Raman spectrum and TGA were performed to prove the success of hybridization. Simultaneously, adhesion, electrochemical, and SEM experiments were conducted to characterize the protective performance of the coating under different ablation times. One noteworthy phenomenon showed by the thermogravimetric analysis results is that the initial decomposition temperature of Al2O3-MWCNTs was increased by 100 °C compared with pure MWCNTs, which provided a basis for the application of the ceramic coatings in oxidation-resistant environment at 600 °C. The results of adhesion experiments showed that the dry bonding force of the ceramic coating with Al2O3-MWCNTs added on the substrate /coating interface was 3 times higher than that of the pure coating. By adding Al2O3-MWCNTs, the coating had a denser mosaic structure on the outside a three-dimensional mesh structure on the inside, which provided outstanding shielding properties and more electron channels, and had the best surface quality after ablation at 600 ℃. Additionally, the Rct value was 34.7 kΩ/cm2 after 100 h of high temperature ablation, which is 345 times of that without added coating. In general, the results showed that the corrosion resistance of the coating with Al2O3-MWCNTs as the reinforcing phase was still maintained at a high level.
The genetic effect on plant growth by plasma immersion ion implanter after implantation on pea seed was studied. The results of the seed treated not only showed the germination percentage decline but also the plant growth retardation, and the stem of a plant was low. The semilethal dosage was 20 minutes. An economical and effectine method of plasma immersion ion implantation in mutagenic breeding is proposed.
The selective course Navigation Positioning Technology,newly offered for the students majoring in mechatronics engineering and simulation engineering,has the obvious characteristics of wide scope and information,which is a real challenge to fresh teachers in completing the teaching task within limited class hours while assuring the effect. Several suggestions are put forward to improve classroom teaching effect within current class hours according to the above conditions.
Myocardial infarction (MI) is a severe disease with high mortality worldwide. However, regenerative approaches remain limited and with poor efficacy. The major difficulty during MI is the substantial loss of cardiomyocytes (CMs) with limited capacity to regenerate. As a result, for decades, researchers have been engaged in developing useful therapies for myocardial regeneration. Gene therapy is an emerging approach for promoting myocardial regeneration. Modified mRNA (modRNA) is a highly potential delivery vector for gene transfer with its properties of efficiency, non-immunogenicity, transiency, and relative safety. Here, we discuss the optimization of modRNA-based therapy, including gene modification and delivery vectors of modRNA. Moreover, the effective of modRNA in animal MI treatment is also discussed. We conclude that modRNA-based therapy with appropriate therapeutical genes can potentially treat MI by directly promoting proliferation and differentiation, inhibiting apoptosis of CMs, as well as enhancing paracrine effects in terms of promoting angiogenesis and inhibiting fibrosis in heart milieu. Finally, we summarize the current challenges of modRNA-based cardiac treatment and look forward to the future direction of such treatment for MI. Further advanced clinical trials incorporating more MI patients should be conducted in order for modRNA therapy to become practical and feasible in real-world treatment.
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