Xiaoqing Wang

Harvard University

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Martin Uecker

German Centre for Cardiovascular Research

Nick Scholand

Graz University of Technology

Zhengguo Tan

Advanced Imaging Research (United States)

Volkert Roeloffs

Universitätsmedizin Göttingen

Sebastian Rosenzweig

Universitätsmedizin Göttingen

Moritz Blumenthal

Graz University of Technology

Jens Frahm

Max Planck Institute for Biophysical Chemistry

H. Christian M. Holme

Graz University of Technology

Berkin Bilgiç

Massachusetts General Hospital

Dirk Voit

Max Planck Institute for Biophysical Chemistry

Cooperative Institutions

Chinese Academy of Medical Sciences & Peking Union Medical College

Sun Yat-sen University

Chinese Academy of Sciences

Shandong University

Universitätsmedizin Göttingen

Shanghai Jiao Tong University

Peking University

German Centre for Cardiovascular Research

University of Göttingen

Fudan University

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Investigation of the cognitive levels and health education on elderly patients with acute myocardial infarction

Zhongguo jiceng yiyao (2009)

Xiaoqing Wang Yu-xi Du Chun-wo Liu

Objective We observed the level of education of elderly patients with acute myocardial infarction (ami) influenced the level of awareness in the disease.Methods we used the questionnaire designed by ourselves to investigate the cognitive level of 80 cases with acute myocardial infarction.According to the education level of the patients,we divided them into different groups,including junior high group,secondary technical group,junior college group,and compared the different awareness levels of the three groups of patients with each other.Results The rate that the junior college group patients with AMI did not understand the risk factors were:diet70%,body weight 50%,smoking 70%,exercise40%,lipids 50%,blood pressure80%,blood sugar 50%,significantly lower than that of the secondary technical group of 38%,33%,47%,38%,42%,71%,42% and of the junior high school group,of 22%,18%,48%,16%,14%,45%,18% ( all P ＜ 0.05 ),The awareness of the disease in the junior college group of AMI was significantly higher than the secondary technical group and the junior high school group( all P ＜ 0.05 ).Conclusion The level of education and awareness of the disease in elderly patients with AMI was significantly related. Key words: Myocardial infarction; Cognitive science; Health education; Aged

Blood sugar

10.3760/cma.j.issn.1008-6706.2009.02.042

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Data for: Physics-based Reconstruction Methods for Magnetic Resonance Imaging

Zenodo (CERN European Organization for Nuclear Research) (2020)

Xiaoqing Wang Zhengguo Tan Nick Scholand Volkert Roeloffs Martin Uecker

Magnetic Resonance Imaging measurement data used in our paper about 'Physics-based Reconstruction Methods for Magnetic Resonance Imaging'

10.5281/zenodo.4060287

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Regularization technique for pre-stack seismic data and its application in reverse time migration

International Geophysical Conference, Beijing, China, 24-27 April 2018 (2018)

Lu Xu Bo Li Xiaoqing Wang

Due to the limitation of acquisition cost and complex geological conditions, seismic data can not be regularly sampled, so that the seismic data can not meet the actual processing requirements. Spatial irregular data will affect the application effect of stacking and other data processing, which will cause serious spatial aliasing and reduce imaging accuracy.In this paper, a suitableregularization forreverse time migrationis proposed, which is implemented in the OVT domain, with antileakage, antialiasing and antinoise.The output is shot gather by the coordinate mapping relationship. The practical application shows that the technique can effectively improve the imaging accuracy of reverse time migration while saving the acquisition cost.

Seismic migration

Regularization

10.1190/igc2018-086

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Calcium desensitizer catechin reverses diastolic dysfunction in mice with restrictive cardiomyopathy

Archives of Biochemistry and Biophysics (2015)

Lei Zhang Changlong Nan Yuan Chen Jie Tian Pierre‐Yves Jean‐Charles

Diastolic heart failure

10.1016/j.abb.2015.03.015

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Citations (24)

Model‐based reconstruction for simultaneous multi‐slice mapping using single‐shot inversion‐recovery radial FLASH

Magnetic Resonance in Medicine (2020)

Xiaoqing Wang Sebastian Rosenzweig Nick Scholand H. Christian M. Holme Martin Uecker

Purpose: To develop a single-shot multi-slice T1 mapping method by combing simultaneous multi-slice (SMS) excitations, single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH) and a nonlinear model-based reconstruction method. Methods: SMS excitations are combined with a single-shot IR radial FLASH sequence for data acquisition. A previously developed single-slice calibrationless model-based reconstruction is extended to SMS, formulating the estimation of parameter maps and coil sensitivities from all slices as a single nonlinear inverse problem. Joint-sparsity constraints are further applied to the parameter maps to improve T1 precision. Validations of the proposed method are performed for a phantom and for the human brain and liver in six healthy adult subjects. Results: Phantom results confirm good T1 accuracy and precision of the simultaneously acquired multi-slice T1 maps in comparison to single-slice references. In-vivo human brain studies demonstrate the better performance of SMS acquisitions compared to the conventional spoke-interleaved multi-slice acquisition using model-based reconstruction. Apart from good accuracy and precision, the results of six healthy subjects in both brain and abdominal studies confirm good repeatability between scan and re-scans. The proposed method can simultaneously acquire T1 maps for five slices of a human brain ($0.75 \times 0.75 \times 5$ mm$^3$) or three slices of the abdomen ($1.25 \times 1.25 \times 6$ mm$^3$) within four seconds. Conclusion: The IR SMS radial FLASH acquisition together with a non-linear model-based reconstruction enable rapid high-resolution multi-slice T1 mapping with good accuracy, precision, and repeatability.

Single shot

Accuracy and precision

10.1002/mrm.28497

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An Open-Source Self-navigated Multi-Echo Gradient Echo Acquisition for R2* and QSM mapping using Pulseq and Model-Based Reconstruction

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2024)

Xiaoqing Wang Berkin Bilgic̦Daniel Gallichan Kwok‐Shing Chan José P. Marques

We propose an open-source multi-echo GRE sequence and reconstruction algorithms for rapid acquisition and harmonization of QSM. This is implemented using Pulseq, where different sampling patterns are used across echoes to provide complementary information and facilitate the proposed MOdel BAsed (MOBA) reconstruction. MOBA estimates M0, R2* and frequency maps using nonlinear optimization and is implemented in BART to facilitate dissemination. B0 correction is performed using 1D navigators acquired during the crusher gradients in each repetition. Motion navigators inserted in the sequence permit robust estimation of motion parameters with time frames of ~13seconds, and will lend themselves to retrospective motion correction.

Echo (communications protocol)

Sequence (biology)

10.58530/2023/0402

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Study on the absorption of monosialotetrahexosylganglioside sodium in rats with in situ cycle intestinal perfusion methods

Zhongguo yishi zazhi (2017)

Long Deng Yao Wang Meiling Chen Ying Xiong Jiaqi Luo

Objective To investigate the duodenum absorptive character of monosialotetrahexosylganglioside sodium (GM1) in rats. Methods The contents of phenolsulfonphthalein (as indicators) and GM1 were determined with ultraviolet-visible (UV) method and high performance liquid chromatography (HPLC) method in rats with in situ cycle intestinal perfusion model. Results The ratio of duodenum absorption of GM1 was 10% in 2 h after cycle and 22% in 6 h after cycle, respectively. The Ka was (0.030±0.012)h, and absorption t1/2 was (25.50±8.56)h in 8 h after cycle. Conclusions GM1 is absorption in rat duodenum, and the accumulate absorption of GM1 is almost linearly related to the cycle time. The absorption dynamics of GM1 may be first-order kinetic process. Key words: G(M1) ganglioside/PK; Intestinal absorption; Perfusion

10.3760/cma.j.issn.1008-1372.2017.04.008

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Free-Breathing Liver Fat,R₂* andB₀ Field Mapping Using Multi-Echo Radial FLASH and Regularized Model-Based Reconstruction

IEEE Transactions on Medical Imaging (2022)

Zhengguo Tan Christina Unterberg‐Buchwald Moritz Blumenthal Nick Scholand Philip Schaten

This work introduced a stack-of-radial multi-echo asymmetric-echo MRI sequence for free-breathing liver volumetric acquisition. Regularized model-based reconstruction was implemented in Berkeley Advanced Reconstruction Toolbox (BART) to jointly estimate all physical parameter maps (water, fat, R2*, and B0 field inhomogeneity maps) and coil sensitivity maps from self-gated k-space data. Specifically, locally low rank and temporal total variation regularization were employed directly on physical parameter maps. The proposed free-breathing radial technique was tested on a water/fat & iron phantom, a young volunteer, and obesity/diabetes/hepatic steatosis patients. Quantitative fat fraction and R2* accuracy were confirmed by comparing our technique with the reference breath-hold Cartesian scan. The multi-echo radial sampling sequence achieves fast k-space coverage and is robust to motion. Moreover, the proposed motion-resolved model-based reconstruction allows for free-breathing liver fat and R2* quantification in multiple motion states. Overall, our proposed technique offers a convenient tool for non-invasive liver assessment with no breath holding requirement.

10.1109/tmi.2022.3228075

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Citations (7)

Initial negative concordance on unipolar and bipolar electrograms: a novel parameter for localizing the origin of premature ventricular contractions arising from pulmonary sinus cusps

Journal of Interventional Cardiac Electrophysiology (2023)

Xiaoqing Wang Mengfei Wang Ya-Min Cheng Jie Hui

Concordance

10.1007/s10840-023-01473-4

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Fine‐Grain High‐Performance Densified Oxide Fibers Produced by Open Ultrafast High‐Temperature Sintering

Advanced Materials (2024)

Youmei Wang Weiwei Qin Chen Zhao Zhezhe Deng Dehua Ma

The considerable grain growth occurring during the long-term high-temperature sintering of polycrystalline oxide fibers negatively affects their mechanical properties, which highlights the need for alternative sintering methods. Herein, open ultrafast high-temperature sintering (OUHS) in air, characterized by rapid heating/cooling (>10000 K min

10.1002/adma.202412139

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Citations (1)