Bin Zhang

Guangdong Ocean University

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Changyou Li

Qingdao Agricultural University

Guodong Han

Shihezi University

Mengli Zhao

Inner Mongolia Agricultural University

Longsheng Xing

Hebei University

Jiahua Zheng

Second Hospital of Hebei Medical University

Fanghao Wan

Chinese Academy of Agricultural Sciences

Tian‐Bo Ding

Qingdao Agricultural University

Feng Zhang

University of Shanghai for Science and Technology

Wanqiang Qian

Agricultural Genomics Institute at Shenzhen

Ji Liu

Cotton Research Institute

Cooperative Institutions

Chinese Academy of Sciences

159

University of Chinese Academy of Sciences

Ministry of Agriculture and Rural Affairs

Chinese Academy of Agricultural Sciences

Sun Yat-sen University

Qingdao Agricultural University

Zhejiang University

Chinese Academy of Medical Sciences & Peking Union Medical College

Hainan University

Shanghai Jiao Tong University

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Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy

Human Molecular Genetics (2013)

Jong‐Min Lee Ekaterina I. Galkina Rachel Levantovsky Elisa Fossale Mary Anne Anderson

In Huntington's disease (HD), the size of the expanded HTT CAG repeat mutation is the primary driver of the processes that determine age at onset of motor symptoms. However, correlation of cellular biochemical parameters also extends across the normal repeat range, supporting the view that the CAG repeat represents a functional polymorphism with dominant effects determined by the longer allele. A central challenge to defining the functional consequences of this single polymorphism is the difficulty of distinguishing its subtle effects from the multitude of other sources of biological variation. We demonstrate that an analytical approach based upon continuous correlation with CAG size was able to capture the modest (∼21%) contribution of the repeat to the variation in genome-wide gene expression in 107 lymphoblastoid cell lines, with alleles ranging from 15 to 92 CAGs. Furthermore, a mathematical model from an iterative strategy yielded predicted CAG repeat lengths that were significantly positively correlated with true CAG allele size and negatively correlated with age at onset of motor symptoms. Genes negatively correlated with repeat size were also enriched in a set of genes whose expression were CAG-correlated in human HD cerebellum. These findings both reveal the relatively small, but detectable impact of variation in the CAG allele in global data in these peripheral cells and provide a strategy for building multi-dimensional data-driven models of the biological network that drives the HD disease process by continuous analysis across allelic panels of neuronal cells vulnerable to the dominant effects of the HTT CAG repeat.

10.1093/hmg/ddt176

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Citations (29)

Biology, invasion and management of the agricultural invader: Fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae)

Journal of Integrative Agriculture (2021)

Jing Wan Cong Huang Changyou Li Hongxu Zhou Yonglin Ren

The fall armyworm (FAW), Spodoptera frugiperda (J. E. Smith), is native to the Americas. It has rapidly invaded 47 African countries and 18 Asian countries since the first detection of invasion into Nigeria and Ghana in 2016. It is regarded as a super pest based on its host range (at least 353 host plants), its inherent ability to survive in a wide range of habitats, its strong migration ability, high fecundity, rapid development of resistance to insecticides/viruses and its gluttonous characteristics. The inherently superior biological characteristics of FAW contribute to its invasiveness. Integrated pest management (IPM) of FAW has relied on multiple applications of monitoring and scouting, agricultural control, chemical pesticides, viral insecticides, sex attractants, bio-control agents (parasitoids, predators and entomopathogens) and botanicals. Knowledge gaps remain to be filled to: (1) understand the invasive mechanisms of S. frugiperda; (2) understand how to prevent its further spread and (3) provide better management strategies. This review summarizes the biological characters of FAW, their association with its invasiveness and IPM strategies, which may provide further insights for future management.

Fall armyworm

10.1016/s2095-3119(20)63367-6

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Citations (157)

Application of apparent stress to macroseism tendency prediction in western China's mainland

Earthquake (2007)

Bin Zhang

This paper takes western China's mainland(20°~50°N,73°~105°E)as an example,based on the monthly earthquake catalogue of CENC and referring to the Harvard CMT catalogue,chooses 191 earthquakes in China's mainland from January 1,1990 to December 31,2005 to compare the apparent stress value σapp1 which are calculated by using Harvard's seismic moment and magnitude-energy expressions with the apparent stress value σapp2 which are calculated by using the magnitude experiential expressions only.Based on that,this paper researched the relation between apparent stress anomalous area and macroseismic area through summarizing macroseism MS≥7 in China's mainland since1970 and graded the R-value according to the macroseism area prediction of ICD yearly prediction report.The result shows that,① When the magnitude upper limit is fixed,the variance of difference sequence between σapp1 and σapp2 increases along with the magnitude lower limit increase.In 3.5 ≤MS ≤ 6.0 sectors,the fitting degrees of σapp1 and σapp2 are better.② The change and migration of apparent stress anomalous area is possibly the reflection of the change and migration of the remarkable stress variation area in the whole structure stress area.It have many advantages,for example,the picture may directly view,it can be quantified,the prediction of area is limited and so on,which could be used to predict the microseism area.The R-value approximately is 0.35.Finally,this paper discusses the idea on the tendency prediction of macroseism area.

Value (mathematics)

China mainland

Mainland

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Citations (1)

Exposure to hypomagnetic field space for multiple generations causes amnesia in Drosophila melanogaster

Neuroscience Letters (2004)

Bin Zhang Huimin Lu Xi Wang Xianju Zhou Shiyu Xu

Memory Formation

Mushroom bodies

Memory Impairment

10.1016/j.neulet.2004.08.072

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Citations (58)

Influence of Two Frying Methods on the Quality and Flavor of Hairtail

DOAJ (DOAJ: Directory of Open Access Journals) (2022)

Yixuan Ding Ting Zhou Yueqin Liao Huimin Lin Bin Zhang

10.13386/j.issn1002-0306.2022030023

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Citations (0)

Plant compensatory growth in aspen seedlings: the role of frequency and intensity of herbivory and resource availability

Nadir Erbilgin David A. Gálvez Bin Zhang

Plant ecologists have debated the mechanisms used by plants to cope with the impact of herbivore damage for more than a century. During that time, plant resistance mechanisms, which reduce the amount of herbivore damage before and during herbivory, have received most of the attention, while plant tolerance mechanisms, which may minimize the impacts of damage after herbivory, have been less studied. The aim of this presentation is to bring the topic of plant compensatory responses, especially compensatory growth, to the front of research in plant ecology and plant-herbivore interactions. We conducted a greenhouse experiment to evaluate how carbon sink-source relationships and compensatory plant growth operate under different intensities and frequencies of simulated defoliation of aspen seedlings, with or without N-enriched media. We found large variations in plant responses, ranging from undercompensatory to overcompensatory growth, depending on the resource availability and defoliation intensity and frequency. We developed a new predictive model, the Frequency and Intensity of Herbivory and Resource Availability (FIRA), based on carbon sink-source relationships. Our model incorporates the interactions between frequency and intensity of herbivory and resource availability as modulators of plant compensatory responses. We concluded by discussing the results of this and earlier studies in the context of the FIRA model, and elaborated the intricate relationship between resource availability and compensatory growth following herbivory.

Compensatory growth (organ)

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Establishment and characterization of the Bactrocera dorsalis (Diptera: Tephritidae) embryonic cell line QAU-Bd-E-2

In Vitro Cellular & Developmental Biology - Animal (2021)

Guiling Zheng Jie Li Qianlong Yu Bin Zhang Xue-Meng Ding

Bactrocera Dorsalis

10.1007/s11626-021-00619-w

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Citations (4)

Content Analysis and Safety Evaluation of Organochlorine Pesticides in Economic Shellfish from Shandong Coastal Areas

Shandong Agricultural Sciences (2010)

Bin Zhang

The residue of organochlorine pesticides(HCHs、DDTs) in 20 samples of shellfish collected from the marine product markets in Shandong coastal areas in April and October,2008 were detected by GC-ECD and calculated by the external standard method.The results showed that no HCHs was detected and the detection rate of DDTs was 35%,which were not above the related national standards and lower than those in other sea areas in China.The pollution situation was evidently improved compared with that in 2005.Most part of DDTs were pp'-DDD and pp'-DDE,which indicated that there was no new pollution source to be input recently and the decomposed DDTs were mainly caused by aerobic degradation.

National standard

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DIS/REORIENTATION OF CHINESE INTERNATIONAL STUDENTS’ RACIAL AND ETHNIC IDENTITIES IN THE U.S.: COMMUNICATING RACE AND ETHNICITY IN THE GLOBAL-LOCAL DIALECTIC

Bin Zhang

Dialectic

Ethnic chinese

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Citations (2)

The association of sleep quality and night sleep duration with coronary heart disease in a large-scale rural population