Abstract Objective To understand the reasons for failure of smoking cessation among community smokers in Beijing, and analyze the influencing factors of the reasons for failure to quit, in order to provide a reference for providing smoking cessation guidance services. Method Based on a cross-sectional study, a one-to-one questionnaire was used. The survey included basic demographic information, tobacco use, and past attempts to quit. And descriptive analysis was used to analyze the distribution of the reasons for the failure of smoking cessation. c 2 test or Fisher's exact probability method were used to analyze the causes of smoking cessation failure, demographic indicators, tobacco use and other factors. Correspondence analysis was used to further explore the relationship between each factor and the reasons for smoking cessation failure. Result A total of 442 smokers who had tried to quit smoking were investigated. The top three reasons for failure to quit were difficulty in controlling addiction, insufficient self-willingness (54.3%), the effects of other smokers(35.3%), and lack of smoke-free support environment(26.0%). There were statistically significant differences in the distribution of the reasons for failure of smoking cessation among different ages, occupations, and discomforts during smoking cessation(All P <0.05). Correspondence analysis results show that the reasons for failure of smoking cessation among smokers aged 19-30 are mainly work or study stress. There are differences in the reasons why smokers in different occupations fail to quit smoking; The influence of other smokers and the lack of a smoke-free support environment are closely related to the desire to quit during the process of quitting. Conclusion Work or study pressure, the influence of other smokers and the lack of smoke-free support environment are the main reasons for the failure of smoking cessation attempts. Therefore, it is suggested to strengthen education in different occupational places and implement personalized smoking cessation education. It is recommended to provide tips on coping with smoking cessation and alleviating peer pressure in social situations, as well as help for stress coping and negative emotion relief in smoking cessation guidance. At the same time, it is essential to strengthen the shaping of a smoke-free support environment.
Objective
To investigate smoking cessation behaviors and factors influencing it among adult community smokers in Beijing.
Methods
This was a cross-sectional epidemiological study. A questionnaire survey was administered among community smokers over 18 years old, in which information on basic demographics, tobacco use, attempts to quit smoking, tobacco-related awareness, and environmental assessment of smoking cessation support were collected. Descriptive analysis was conducted on the basic information, smoking situation, and demand for smoking cessation intervention of the respondents. Two tests were used to examine the quitting attempts of respondents. Tobacco attempts was found to be correlated with socio-demographic indicators, and factors such as tobacco use, awareness of tobacco-related issues, and the smoking cessation support environment. Dual logistic regression was used to further explore the dependence of identified factors and attempted smoking cessation behavior.
Results
A total of 449 respondents were enrolled in this study, 410 of them were men (91.3%). Among the respondents, 272 people (60.6%) had tried to quit smoking and 177 people (39.4%) did not try to quit smoking. Monthly income level, tobacco-related awareness, degree of surrounding people supporting smoking cessation, whether medical treatment was sought in the previous year, number of visits, whether to persuade medical staff to quit smoking in the past year, and whether smoking was given up in the past year were the identified factors. These seven factors, such as whether they have been asked about smoking, are the influencing factors in trying to quit smoking（P<0.05）. Under the logistic regression model, monthly income level (OR=1.271, 95%CI:1.081-1.493), the support of people around them to quit smoking (OR=1.251, 95%CI:1.035-1.512), and the suggestion of medical personnel in the past year (OR=2.382, 95%CI: 1.054-5.381) were found to encourage attempts to quit smoking.
Conclusion
Factors such as health status, environmental support, hazard perception, and economic level influence attempts to quit smoking. Lack of self-determination and other people's influence are the main reasons for failing to quit smoking. Taking community places as the basic unit of intervention combined with professional guidance of smoking cessation clinic doctors and forming an online comprehensive linkage smoking cessation hospital community intervention model is an innovative way to optimize the management of tobacco dependence.
Key words:
Smoking cessation; Behavior; Influencing factors; Quit attempt
To optimize the prenatal diagnosis platform by using domestically made fluorescence in situ hybridization(FISH) kit and to explore the clinical application of FISH to rapid prenatal diagnosis of a wide range of chromosomal abnormalities.Amniotic fluid samples from 110 pregnant women were studied with the rapid prenatal diagnosis method of FISH and the conventional cell culture method of karyotyping, the results from both methods were compared.Four cases of trisomy 21, 1 case of trisomy 18, 58 cases of 46, XX, and 47 cases of 46, XY were detected by FISH in the 110 amniotic fluid samples. It is concordant with the results from conventional karyotype analysis. The concordance rate is 100%.Domestically made FISH kit can be used to rapidly and accurately detect the most common chromosome aneuploidies by using less sample volume while the price is relatively low. FISH can be a reliable and rapid prenatal diagnostic tool as an adjunct to classical cytogenetic study. It can be used for rapid and accurate prenatal diagnosis of women with high risk of maternal serum screening.
The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot.
Medical devices are essential for the practice of modern medicine, and the standard open-source integrated clinical environment (OpenICE) has been well designed and widely adopted to improve their interoperability. With OpenICE, it is easy to connect individual devices into the integrated clinical system to provide a coherent patient care. In this paper, we present ICERV, the first online verification approach for the OpenICE, to ensure the dependability (mainly for the safety and security) of the integrated system and the involved patient and clinician. The key idea is to customize runtime verification technique to provide a transparent verifying infrastructure to continually intercept the communication commands and messages of those devices, based on which, we can formalize the safety and security requirements as past time linear temporal logic expressions for verifier generation and online formal verification. If any requirements violate, predefined warnings or exception handling actions will be triggered timely to prevent hazards and threats. We have implemented and seamlessly integrated the approach without any changes to the source code of OpenICE nor the code of the upper-level applications or supervision, and the real device is used for evaluation to demonstrate the effectiveness.
Based on newcomers' authentic self-expression perspective (Cable, Gino, & Staats, 2013), this study examined how leader humor actions were related to new hires' proactive socialization behaviors (i.e., relationship building with supervisor and job crafting) over the entry period of organizational socialization process. Five-wave data were collected from 202 newcomers over the first 5-month in their new jobs. The results supported our hypothesized model in three important ways. First, the change in leader humor actions was positively related to the changes in newcomer relationship building with supervisor and job crafting behaviors over time. Second, the effects of leader humor change were through the mechanism of newcomer authentic self-expression change. Third, newcomer positive affectivity had a moderating effect on the relationship between leader humor change and newcomer authentic self-expression change over time. Important theoretical and practical implications are discussed.
The representative SARS-CoV-2 3CL pro inhibitors reported since 2020 and their biological activities and binding models are reviewed, providing new insights into the design and development of more effective 3CL pro inhibitors against SARS-CoV-2.
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