G A Shun-Shin

New Cross Hospital

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Nicholas Brown

Carl Hayden Bee Research Center

Anthony J. Bron

University of Oxford

J M Sparrow

Bristol Eye Hospital

Nicholas A. Brown

Binghamton University

B. Willekens

Netherlands Institute for Neuroscience

Gijs F.J.M. Vrensen

Leiden University Medical Center

Nicola Brown

Australian Catholic University

N J Price

University of South Australia

Lizette Mowatt

University Hospital of the West Indies

C.F. Arlett

University of Sussex

Cooperative Institutions

University College London

University of Oxford

Ophthalmology Associates (United States)

Moorfields Eye Hospital

Moorfields Eye Hospital NHS Foundation Trust

Nuffield Orthopaedic Centre

Birmingham and Midland Eye Centre

University of California, San Francisco

University of Sussex

University of Miami

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Spectral domain optical coherence tomography findings in retinal folds associated with posterior microphthalmos

Journal of American Association for Pediatric Ophthalmology and Strabismus (2012)

Thomas E. Jackson Yit C. Yang G A Shun-Shin

Microphthalmos

External limiting membrane

Internal limiting membrane

Posterior pole

Limiting

10.1016/j.jaapos.2012.02.020

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Citations (16)

Light scatter from the central human cornea

Eye (1990)

George Smith Nicholas A. Brown G A Shun-Shin

Scheimpflug principle

Human eye

10.1038/eye.1990.81

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Citations (56)

Capsular 'pits' in the human lens.

British Journal of Ophthalmology (1992)

Martin L. Harris Neil Brown G A Shun-Shin Guy T. Smith

The lens capsule is an atypical basement membrane surrounding the lens epithelial cells and lens fibres which make up the remainder of the human lens. A seemingly unreported morphological change visible in the lens capsule with the biomicroscope is described.

Lens capsule

Capsule

10.1136/bjo.76.4.248

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Citations (1)

Macula off Retinal Detachments. how Long Can They Wait before it is Too Late

European Journal of Ophthalmology (2005)

Lizette Mowatt G A Shun-Shin Supriya Arora N J Price

Purpose To determine the association between the duration of macula off detachment and the visual outcome following corrective surgery. Methods Retrospective review of the medical records of patients who underwent surgery for macula off detachment over a 5 year period (April 1994– March 1999). Results There were 104 patients in the study. Patients with macula off detachments wait a mean of 2.6 weeks (±0.3 SE mean) before presentation and 1.8 weeks (±0.2 SE of mean) thereafter before surgery. The mean duration of detachment prior to surgical repair was 4.2 weeks (±0.3 SE mean). 78% of patients achieved a postoperative improvement in visual acuity. 36.5% achieved functional visual success of 6/12 at 3 months, which increased to 51% at final discharge. There was no significant difference in visual outcomes for patient undergoing internal vs external procedures (p=0.188). The preoperative visual acuity was the most significant predictor of post operative visual acuity (p<0.0005). Less than 40% of macula off detachments of =6 weeks duration will achieve a vision of 6/12 or better compared with 68.2% of patients with macula off detachments of ≤1 week. Conclusions The best mean postoperative vision (LogMAR 0.35) was seen in patients with detachment of <1 week duration. Patients <60 years are more likely to achieve visual improvement despite the duration of the detachment. Macula off detachments of >6 weeks duration have a significantly poor postoperative visual prognosis. Awareness of this visual prognosis can assist in planning the timing of surgery to ensure an acceptable result.

10.1177/112067210501500117

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Citations (35)

Dynamic nature of posterior subcapsular cataract.

British Journal of Ophthalmology (1989)

G A Shun-Shin Nicholas Brown Anthony J. Bron J M Sparrow

Posterior subcapsular cataracts were studied in 10 patients (19 eyes) and were photographed at four to 12 weeks intervals by the Oxford Retroillumination Camera. Changes in the fine structure of PSC may occur in as short a time as four weeks. Posterior subcapsular cataracts are shown to be in a state of flux and are not, as might be assumed, slowly but relentlessly progressive. This could imply the existence of a repair mechanism in the lens.

10.1136/bjo.73.7.522

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Citations (36)

Dissociated eye movements in craniosynostosis: a hypothesis revived.

British Journal of Ophthalmology (1993)

Han Cheng Michael Burdon G A Shun-Shin S Czypionka

A characteristic pattern of dissociated eye movements was observed in a large proportion of our patients with a variety of craniosynostosis syndromes. These anomalies simulate overaction of the inferior oblique and underaction of the superior oblique muscles which, however, cannot fully explain the abnormalities. In a number of cases, excyclorotation of the muscle cone was observed, with the upper pole of the eye tilted away from the midline. It is postulated that such excyclorotation of the eyes will lead to dissociated eye movements which can be explained on physiological grounds according to Hering's law. This paper presents a review of our patients and evidence to support this hypothesis.

Inferior oblique muscle

Superior oblique muscle

10.1136/bjo.77.9.563

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Citations (49)

Ethnic differences in the demand incidence of retinal detachments in two districts in the West Midlands

Eye (2003)

Lizette Mowatt G A Shun-Shin N J Price

10.1038/sj.eye.6700245

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Citations (56)

Why outpatient initiative clinics fail to deliver: an analysis by mathematical model

Eye (2004)

G A Shun-Shin Matthew Shun‐Shin

Outpatient visits

10.1038/sj.eye.6700727

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Citations (0)

Relationship ofcataract toradiation sensitivity

Nicholas A. Brown G A Shun-Shin Paul D. Lewis W.A. Cramp C.F. Arlett

SUMMARY Considerable exposuretoradiation always causesposterior subcapsular cataract (PSC). Thisinvestigation wasconducted toascertain whether cellular hypersensitivity toradiation may beidentified asa possible causeofcataract inpersonsexposed tolowlevels ofradiation. Patients werestudied inwhomPSChadfollowed probable exposuretolowlevels ofradiation orin whomPSChaddeveloped before the ageof60without knownexposure.Thepatients with cataract were compared with ageandsexmatched controls without cataract. Radiation sensitivity was estimated bymeasuring clonal growth ofskin fibroblasts andperipheral bloodlymphocytes after exposuretograded dosesofradiation andbymeasuring postirradiation reconstruction of separated nuclear material fromlymphocytes. Theresults showvariations inthelevel ofradiation sensitivity between thepatients, without significant differences fromthecontrols. Itisconcluded thatradiation hypersensitivity,

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Spontaneous reabsorption of a rubella cataract.

British Journal of Ophthalmology (1990)

Guy T. Smith G A Shun-Shin Anthony J. Bron

AbstractA case of spontaneous reabsorption of a rubella cataract is presented. The morphology of the capsular bag is recorded by Scheimpflug slit image and retroillumination photography.

10.1136/bjo.74.9.564

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Citations (15)