Journal Article Skin Tumorigenic Potential of Crude and Refined Coal Liquids and Analogous Petroleum Products Get access H. P. WITSCHI, H. P. WITSCHI *Biology DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar L. H. SMITH, L. H. SMITH *Biology DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar E. L. FROME, E. L. FROME †Engineering, Physics, and Mathematics DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar M. E. PEQUET-GOAD, M. E. PEQUET-GOAD *Biology DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar W. H. GRIEST, W. H. GRIEST ‡Analytical Chemistry DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar C.-H. HO, C.-H. HO ‡Analytical Chemistry DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar M. R. GUERIN M. R. GUERIN ‡Analytical Chemistry DivisionOak Ridge National Laboratory, Oak Ridge, Tennessee 37831 Search for other works by this author on: Oxford Academic PubMed Google Scholar Toxicological Sciences, Volume 9, Issue 2, August 1987, Pages 297–303, https://doi.org/10.1093/toxsci/9.2.297 Published: 01 August 1987
Abstract The use of gas chromatography with flame photometric detection provides a convenient means of detecting sulfur-containing compounds in the gas phase of cigarette smoke. Application of the method casts doubt on currently held views about the composition of the sulfur-containing portion of smokes.
With minor modifications a conventional potentiometric recorder (Leeds and Northrup) can be used to regulate the temperature of a furnace up to 1200 degrees C. These alterations are mainly based on the following. A second potentiometer (recopier) is attached to the shaft of the main potentiometer and the voltage is stabilized through a triac semiconductor and photocells. The input available to the furnace is monitored by a triac semiconductor. Greater temperature stability and precision of the order of +or-0.2 degC is achieved; the relative error being smaller as temperature is increased.
Direct thermal desorption of analytes into an ion trap mass spectrometer (ITMS) is being investigated as a technique for the rapid screening of a wide variety of samples for target semivolatile organic compounds. This includes the direct detection of drugs in physiological fluids, semivolatile organic pollutants in water and waste samples, and air pollutants collected on sorbent cartridges. In order to minimize the analysis time, chromatographic separation is not performed on the sample prior to introduction into the ITMS. Instead, selective chemical ionization and tandem mass spectrometry (MS/MS) are used achieve the specificity required for the target analytes. Detection limits are typically 10--50 ppb using a 1 uL aliquot of a liquid sample without preconcentration. Sample turn-around time is 2 to 5 minutes and 3 to 5 target analytes can be quantitatively determined simultaneously. 6 figs.
Journal Article Routine Gas Chromatographic Component Profiling of Cigarette Smoke for the Identification of Biologically Significant Constituents Get access M. R. Guerin, M. R. Guerin Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Olerich, G. Olerich Search for other works by this author on: Oxford Academic PubMed Google Scholar A. D. Horton A. D. Horton Tobacco Smoke Research Program, Analytical Chemistry Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Chromatographic Science, Volume 12, Issue 7, July 1974, Pages 385–391, https://doi.org/10.1093/chromsci/12.7.385 Published: 01 July 1974 Article history Received: 09 November 1973 Published: 01 July 1974
The role of the EPA/DOE Fossil Fuels Research Materials Facility in this study is to actively support and coordinate the health effects investigations of this oil shale development by acting as a central point for acquisition, cataloging, storage, and distribution of referenceable materials for study. In addition, selected materials are chemically fractionated for bioassay and are characterized in additional detail beyond that of routine stability monitoring. Finally, the Facility is acting as an information transfer agent to insure that the results of the investigations are made available to the oil shale industry and the funding agencies. This paper is concerned with the sample management and characterization aspect of the Facility's role in this study.
Environmental and health issues must be addressed as an integral part of synfuels technology development. To this end, the US Environmental Protection Agency, the Department of Energy, Department of Defense (US Navy), the American Petroleum Institute, Development Engineering, Inc., and the Standard Oil Company are cooperating in an interagency matrix approach investigation of the potential health effects associated with the production and refining of shale oil into jet and diesel fuels. Groups of biologists, ecologists, and chemists in laboratories across the nation are involved in this multidisciplinary research effort. This volume is a record of the findings to date as presented at the symposium, Health Effects Investigation of Oil Shale Development, held at Gatlinburg, Tennessee, June 23-24, 1980. The progress summarized here illustrates the success of the matrix approach and suggests that other materials and technologies can be similarly studied. Separate abstracts have been prepared of each item for inclusion in the Energy Data Base.
