Y. Leroy

Carrier (United States)

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A. Mamouni

Hôpital Cardiologique du Haut-Lévêque

Bernard Fournet

École Nationale Supérieure de Chimie de Lille

J.C. van de Velde

Institut d'électronique de microélectronique et de nanotechnologie

B. Bocquet

Université de Lille

Jean Montreuil

McGill University

Gérard Strecker

Centre National de la Recherche Scientifique

T. Lasri

Centre National de la Recherche Scientifique

Jean‐Claude Michalski

Unité de Glycobiologie Structurale et Fonctionnelle

Jean‐Pierre Zanetta

Centre National de la Recherche Scientifique

Yann Guérardel

Gifu University

Cooperative Institutions

Centre National de la Recherche Scientifique

176

Université de Lille

Inserm

Unité de Glycobiologie Structurale et Fonctionnelle

Université d'Artois

Laboratoire de Chimie

École Nationale Supérieure de Chimie de Lille

Institut d'électronique de microélectronique et de nanotechnologie

Université Paris Cité

Université Lille Nord de France

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Structural analysis of the carbohydrate chains of β-N-acetylhexosaminidases from bovine brain

Biochemical Journal (1985)

B. Overdijk E.P. Beem Gé J. Van Steijn L A W Trippelvitz Jan J.W. Lisman

The oligosaccharide structures of bovine brain beta-N-acetylhexosaminidases A and B (EC 3.2.1.30) were studied at the glycopeptide level by employing 500 MHz 1H-n.m.r. spectroscopy and methylation analysis involving g.l.c.-m.s. More than 90% of the chains were found to be of the oligomannoside type, containing, on average, five to six mannose residues. Biantennary N-acetyl-lactosamine-type chains terminated in N-acetylneuraminic acid were found to comprise the remaining 5-10% of the total carbohydrate. The isoenzyme forms A and B do not differ from each other in the structure of their carbohydrate moiety, but do deviate in carbohydrate content and, in consequence, in the number of carbohydrate chains per molecule.

Oligosaccharide

Carbohydrate conformation

10.1042/bj2320637

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Citations (22)

Quantitative retrieval of temperature of breast cancers by microwave radiometric imaging (MWI)

B. Bocquet S. Mouty R. Ringot Y. Leroy N. Rocourt

The authors have developed a fast MicroWave radiometric Imaging system (MWI) which realizes thermal images with a good spatial resolution. The authors are undertaking at the present time a large scale clinical evaluation of this system for early stage breast tumor characterization. A Receiver Operating Curve (ROC) statistical analsis of an intermediate stage of 60 patients gives a sensibility and a specificity of up to 80%. The authors show here that this technique can sucessfully be used for noninvasive radiological examination in terms of benign-malignant characterization. Moreover, the use of an inverse problem technique in the spatial frequency domain gives a quantitative measurement of cancer temperature. It is now possible to consider a new application such as the following of temperature during a chemotherapy treatment.

Microwave Imaging

Radiometry

Characterization

10.1109/iembs.1999.804275

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Feasibility of nondestructive testing of concrete by microwave radiometry

Microwave and Optical Technology Letters (1997)

Xavier D�robert Ahmed Mamouni Y. Leroy

This study covers the numerical modeling of microwave radiometric signals applied to prestressed concrete in bridge structures. After an overview of the microwave technique, this work looks into the influence of concrete water content on the radiometric signal obtained when the duct is heated locally. Theoretical and experimental investigations have shown that the permittivity of the concrete must be known in order to calculate the coupling parameters between the microwave and the medium in order to obtain correct modeling. © 1997 John Wiley & Sons, Inc.

Radiometry

10.1002/(sici)1098-2760(199701)14:1<17::aid-mop6>3.0.co;2-p

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Citations (1)

Radiofrequency Hyperthermia (13.56 MHz) Associated with Radiotherapy or Chemotherapy in the Treatment of Cancer, with Atraumatic Control by Microwave Thermometry (2.4 GHz)

Springer eBooks (1984)

G Giaux B. Prévost Y. Leroy M. Chivé

10.1007/978-1-4684-7697-2_101

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Citations (0)

Thermal Response of a Lossy Two-Ports to a Correlation Radiometer

Ph. Lauer J.C. van de Velde Y. Leroy

We consider the output signal of a correlation radiometer connected to an isothermal lossy two-ports, such as lossy microstrip lines and coaxial lines filled with a lossy dielectric.

Lossy compression

Coaxial

10.1109/euma.1988.333929

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Citations (2)

Microwave Radiometry Imaging: Characterization of Breast Tumours

The Journal of Photographic Science (1991)

G Giaux J. Delannoy D. Delvalee Y. Leroy A. Mamouni

A microwave imaging (MI) device working at 3 GHz has been used to record temperature images of early breast tumours. 25 patients were investigated prior to surgery. For every patient, the excised tissue was examined histologically. 22 of these patients were found to have only benign lesions using both MI and histology. Histology and MI found a malignant tumour for 3 patients. In all the 25 selected patients we were unable to determine the nature of the tumours by clinical examination, X-ray mammography and cytology. The results of the microwave imaging obtained in this study are therefore encouraging in the detection of cancer

Histology

10.1080/00223638.1991.11737142

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Citations (6)

Separation of oligosaccharides by capillary supercritical fluid chromatography and analysis by direct coupling to high-resolution mass spectrometer: Application to analysis of oligomannosidic N-glycans

Analytical Biochemistry (1990)

Y. Leroy Jérôme Lemoine Guy Ricart Jean‐Claude Michalski Jean Montreuil

Capillary electrophoresis–mass spectrometry

10.1016/0003-2697(90)90674-x

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Citations (17)

<title>Noncontact microwave material characterization</title>

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (2001)

D. Glay T. Lasri Ahmed Mamouni Y. Leroy

In this paper, a nondestructive method for the non-contact characterization of non-planar dielectric objects is presented. Traditionally, this kind of measurements is achieved by using spot-focused antennas associated to a vector automatic network analyzer. In this study, we propose a free space measurement system, fitted out with a classical horn antenna, which demonstrates its usefulness in many practical cases. The permittivity is computed from the reflection coefficient of metal-backed samples of different shapes at 2.45 GHz.

Characterization

10.1117/12.450171

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GC/MS identification and quantification of constituents of bacterial lipids and glycoconjugates obtained after methanolysis as heptafluorobutyrate derivatives

Analytical Biochemistry (2005)

Anne Bohin Franck Bouchart Colette Richet Osarath Kol Y. Leroy

Neuraminic acid

Heptose

Hexosamines

Glycoconjugate

Muramic acid

Quantitative Analysis

10.1016/j.ab.2005.02.017

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Citations (26)

Structure determination of oligosaccharides isolated from Cad erythrocyte membranes by permethylation analysis and 500‐MHz ¹H‐NMR spectroscopy

European Journal of Biochemistry (1985)

Françoise HERKT José Paz Parente Y. Leroy Bernard Fournet Dominique Blanchard

Alkaline borohydride reductive cleavage (beta-elimination) of glycophorin A isolated from one individual of the rare blood group Cad, resulted in the release of six acidic oligosaccharide-alditols which were separated by high-performance liquid chromatography (HPLC) on an alkyl amine silicagel column. The structure of four of them has been determined by the application of methanolysis, methylation analysis and 1H-NMR spectroscopy at 500 MHz. The structures and relative amounts were as follows: oligosaccharide 1: NeuAc(alpha 2-3)Gal(beta 1-3)GalNAc-ol (3.5%); oligosaccharide 3: GalNAc(beta 1-4)[NeuAc(alpha 2-3)]Gal(beta 1-3)GalNAc-ol (10.5%); oligosaccharide 5: NeuAc(alpha 2-3)Gal(beta 1-3)[NeuAc(alpha 2-6)]GalNAc-ol (10.4%); oligosaccharide 6: GalNAc(beta 1-4)[NeuAc(alpha 2-3)]Gal(beta 1-3)[NeuAc(alpha 2-6)]GalNAc-ol (71.2%). The two other oligosaccharides (2 and 4) were obtained in very low amount. The major pentasaccharide (oligosaccharide 6) carries the blood group Cad determinant and is a potent inhibitor of human anti-Sda antibody.

Oligosaccharide

Borohydride

Glycophorin

10.1111/j.1432-1033.1985.tb08628.x

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Citations (29)