Yuk-Ming Tsang

Chang Gung Memorial Hospital

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Jin‐Chuan Sheu

National Taiwan University Hospital

Ding‐Shinn Chen

National Taiwan University

Guan‐Tarn Huang

China Medical University Hospital

Po‐Huang Lee

National Taiwan University Hospital

Chien‐Hung Chen

R.O.C Military Academy

Chang Su

First Affiliated Hospital of Zhengzhou University

Kai‐Hsin Lin

National Taiwan University Hospital

Fu-Chang Hu

National Taiwan University

Liying Wang

The First People's Hospital of Changzhou

Yao‐Hsu Yang

Nanchang University

Cooperative Institutions

Far Eastern Memorial Hospital

National Taiwan University Hospital

National Taiwan University

National Yang Ming Chiao Tung University

Chang Gung University

Chang Gung Memorial Hospital

Luodong Poh-Ai Hospital

Linkou Chang Gung Memorial Hospital

Kaohsiung Chang Gung Memorial Hospital

Ministry of Health and Welfare

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Absolute ethanol embolotherapy for hemangioma with Kasabach-Merritt syndrome.

PubMed (1998)

Yao‐Hsu Yang Ping‐Ing Lee Kai‐Hsin Lin Yuk-Ming Tsang

This report describes a female baby having a hemangioma over the right thigh that had appeared as an irregular bruise since two days old. Severe thrombocytopenia, consumptive coagulopathy, anemia, and heart failure developed at three months old. With a diagnosis of Kasabach-Merritt syndrome, systemic corticosteroid, vincristine, subcutaneous alpha-interferon, and massive plate transfusion were given. However, the platelet count remained low and the skin lesion enlarged gradually. Trans-feeding-arterial embolotherapy with a 5 ml pure ethanol (1 ml/kg) injection was performed at four months of age. Thirty days later, her platelet count recovered and the hemangioma shrunk in size. This case illustrates that absolute ethanol embolotherapy is an effective treatment for hemangioma with Kasabach-Merritt syndrome and may be life-saving for those with lesions refractory to medical therapy.

Kasabach–Merritt syndrome

Consumptive Coagulopathy

Refractory (planetary science)

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Citations (8)

Primary leptomeningeal melanoma

Journal of Clinical Neuroscience (2013)

Zhao-Yu Xie Kevin Li‐Chun Hsieh Yuk-Ming Tsang Wing‐Keung Cheung Chen-Hsi Hsieh

Leptomeninges

Meninges

10.1016/j.jocn.2013.08.018

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Computed tomography arterial portography for assessment of portal vein injury after blunt hepatic trauma

Diagnostic and Interventional Radiology (2015)

Chen-Ju Fu Yon‐Cheong Wong Yuk-Ming Tsang Li-Jen Wang Huan-Wu Chen

Intrahepatic portal vein injuries secondary to blunt abdominal trauma are difficult to diagnose and can result in insidious bleeding. We aimed to compare computed tomography arterial portography (CTAP), reperfusion CTAP (rCTAP), and conventional computed tomography (CT) for diagnosing portal vein injuries after blunt hepatic trauma.Patients with blunt hepatic trauma, who were eligible for nonoperative management, underwent CTAP, rCTAP, and CT. The number and size of perfusion defects observed using the three methods were compared.A total of 13 patients (seven males/six females) with a mean age of 34.5±14.1 years were included in the study. A total of 36 hepatic segments had perfusion defects on rCTAP and CT, while there were 47 hepatic segments with perfusion defects on CTAP. The size of perfusion defects on CT (239 cm3; interquartile range [IQR]: 129.5, 309.5) and rCTAP (238 cm3; IQR: 129.5, 310.5) were significantly smaller compared with CTAP (291 cm3; IQR: 136, 371) (both, P = 0.002).Perfusion defects measured by CTAP were significantly greater than those determined by either rCTAP or CT in cases of blunt hepatic trauma. This finding suggests that CTAP is superior to rCTAP and CT in evaluating portal vein injuries after blunt liver trauma.

Portography

Interquartile range

Blunt trauma

10.5152/dir.2015.14445

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Citations (7)

Predicting the Severity and Prognosis of Trismus after Intensity-Modulated Radiation Therapy for Oral Cancer Patients by Magnetic Resonance Imaging

PLoS ONE (2014)

Li-Chun Hsieh John W. Chen Liying Wang Yuk-Ming Tsang Pei‐Wei Shueng

To develop magnetic resonance imaging (MRI) indicators to predict trismus outcome for post-operative oral cavity cancer patients who received adjuvant intensity-modulated radiation therapy (IMRT), 22 patients with oral cancer treated with IMRT were studied over a two-year period. Signal abnormality scores (SA scores) were computed from Likert-type ratings of the abnormalities of nine masticator structures and compared with the Mann-Whitney U-test and Kruskal–Wallis one-way ANOVA test between groups. Seventeen patients (77.3%) experienced different degrees of trismus during the two-year follow-up period. The SA score correlated with the trismus grade (r = 0.52, p<0.005). Patients having progressive trismus had higher mean doses of radiation to multiple structures, including the masticator and lateral pterygoid muscles, and the parotid gland (p<0.05). In addition, this group also had higher SA-masticator muscle dose product at 6 months and SA scores at 12 months (p<0.05). At the optimum cut-off points of 0.38 for the propensity score, the sensitivity was 100% and the specificity was 93% for predicting the prognosis of the trismus patients. The SA score, as determined using MRI, can reflect the radiation injury and correlate to trismus severity. Together with the radiation dose, it could serve as a useful biomarker to predict the outcome and guide the management of trismus following radiation therapy.

Trismus

10.1371/journal.pone.0092561

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Citations (25)

Ultrasonography of small hepatic tumors using high-resolution linear-array real-time instruments.

Radiology (1984)

Jin‐Chuan Sheu J L Sung Ding‐Shinn Chen Jin-sheng Yu T H Wang

Abdominal ultrasonography using a high-resolution linear-array real-time scanner was compared to computed tomography, celiac arteriography, and radionuclide imaging in 24 patients with a total of 33 hepatocellular carcinomas (HCC), 10 patients with cavernous hemangioma (12 tumors), and 2 patients with metastatic carcinoma of the liver (3 tumors), all smaller than 3 cm. Ultrasound proved to be the most sensitive method of detecting such small tumors. Most small HCCs were hypoechoic and most small hemangiomas hyperechoic. Aspiration cytology and/or biopsy under ultrasound guidance detected 92.3% of HCCs and 100% of hemangiomas. Intraoperative ultrasound was employed in 19 cases of small HCC and aided resection in 8. Real-time ultrasound may play a prominent role in early detection and diagnosis of small HCCs.

10.1148/radiology.150.3.6320260

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Citations (116)

Applicability of staging systems for patients with hepatocellular carcinoma is dependent on treatment method – Analysis of 2010 Taiwanese patients

European Journal of Cancer (2009)

Chien‐Hung Chen Fu-Chang Hu Guan‐Tarn Huang Po–Huang Lee Yuk-Ming Tsang

10.1016/j.ejca.2008.12.025

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Citations (73)

Focal myositis of esophagus: a distinct inflammatory pseudotumor mimicking esophageal malignancy.

PubMed (1997)

I.‐P. Chiang J Wang Yuk-Ming Tsang C. Hsiao

Focal myositis is a benign pseudotumor of skeletal muscle that usually occurs in the soft tissue of the extremities. Clinically, it grows rapidly but usually regresses spontaneously and is often misdiagnosed as a malignancy. We report a case of focal myositis occurring in the upper esophagus and presenting as a rapidly growing submucosal tumor with severe esophageal stenosis and dysphagia. It was misdiagnosed preoperatively as esophageal malignancy. Histologically, it was characterized by the presence of various-sized skeletal muscle fibers with interstitial inflammation and fibrosis. The pathological pictures are identical to polymyositis or dermatomyositis, but the stenosis was relieved after operation without recurrence, and levels of the polymyositis-associated autoantibodies and serum enzymes were not elevated. Therefore, clinical and histological information is needed to make a correct diagnosis.

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Liver Resection Improves the Survival of Patients with Multiple Hepatocellular Carcinomas

Annals of Surgical Oncology (2009)

Ming‐Chih Ho Guan‐Tarn Huang Yuk-Ming Tsang Po‐Huang Lee Ding‐Shinn Chen

HCCS

Surgical oncology

Surgical resection

10.1245/s10434-008-0282-7

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Citations (113)