In Part I, the authors treat the problem of the trimming moment caused by wave-making of. a surface vessel or a submerged body moving through a deep or a shallow water. General expressions are obtained for the trimming moment in each of the above-mentioned cases from Prof. Michell's method as well as from Prof. Havelock's one. The results of numerical calculation carried out for the cases of a yessel of mathematical form and a submerged prolate spheroid show good coincidence with the experimental results qualitatively.In Part II, general expressions are obtained for the wave resistance of a vessel of twin hulls. The results of numerical calculation show that the total effective horsepower can be reduced for a wide range of Froude's number by dividing into twin hulls keeping length, draught and displacement of a vessel constant, provided the distance between hulls is chosen suitably.
1.Five isoenzymes of LDH have been isolated from periodontitis gingiva.2.The activity of LDH3 and LDH4 in periodontitis gingiva increased about 2 fold than that of the normal.3.In the activity of LDH1, LDH2 and LDH5, no difference was observed between normal and periodontitis gingivae.4.As kinetic properties of LDH3 and LDH4 in periodontitis gingiva were identical with those from normal gingiva, net synthesis of these isoenzymes was suggested.
Several members of hematopoietic factors are known to have neuroprotective effects against axotomized motor neuron death. We carried out a study to determine whether interleukin-3 (IL-3) and erythropoietin (EPO) rescue spinal motor neuron death following axotomy. Unilateral sciatic nerve was transected in neonatal rats. Different doses of IL-3, EPO, or vehicle were administered daily for two weeks by intraperitoneal injection. After treatment, the number of spinal motor neurons was determined at the level of L4 segment In comparison with vehicle, both IL-3 (10 microg kg(-1)) and EPO (5.0 mg kg(-1)) significantly prevented the loss of motor neurons. Protective potentials is the same between them. These results suggest that IL-3 and EPO play a role for motor neuron survival in vivo and suggest the potential use of these hematopoietic factors in treating diseases that involve degeneration and death of motor neurons, such as motor neuropathy and amyotrophic lateral sclerosis.
Thyroid function tests were evaluated in 32 patients with amyotrophic lateral sclerosis (ALS) with radioimmunoassay of triiodothyronine, thyroxine, thyroid-stimulating hormone, and free thyroxine. The presence of antithyroid antibody activities were also tested. All patients were found to have normal thyroid values except one, who had low triiodothyronine and all patients had negative for antithyroid antibody activities. The data suggest that ALS could not be related to a thyroid disorder.
Satoyoshi syndrome consists of painful intermittent muscle spasms, alopecia and diarrhea. The age of onset is commonly less than 20 years of age. Adult onset of this syndrome is rare. We report a 65-year-old Japanese woman with Satoyoshi's syndrome of adult onset. Satoyoshi's syndrome of adult onset shows no skeletal abnormalities, in comparison with the classical pediatric cases. The clinical features in our patient revealed the benign and long-term course of muscle spasm and alopecia. This progression differed markedly from the other patients of adult onset. Thus, the severity of Satoyoshi's syndrome is variable in adult onset cases, and this diagnosis should be considered in adults with various and unexplained muscle spasms.