Ai Yan Wang

University of Gdańsk

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Agnieszka Szalewska-Pałasz

University of Gdańsk

Dariusz Nowicki

University of Gdańsk

Magdalena Narajczyk

University of Gdańsk

Monika Karczewska

University of Gdańsk

Bartosz Słomiński

Gdańsk Medical University

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University of Gdańsk

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

Laboratory of Molecular Genetics

Umeå University

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institutes of Health

Jagiellonian University

Józef Piłsudski University of Physical Education in Warsaw

Częstochowa University of Technology

Institute of Psychology and Pedagogy

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Antibacterial activity of t-cinnamaldehyde: an approach to its mechanistic principle towards enterohemorrhagic Escherichia coli (EHEC)

Phytomedicine (2024)

Monika Karczewska Ai Yan Wang Magdalena Narajczyk Bartosz Słomiński Agnieszka Szalewska-Pałasz

Compounds of natural origin are potent source of drugs with unique mechanisms of action. Among phytochemicals, trans-cinnamaldehyde (t-CA) exhibits a wide range of biological activity, thus has been used for centuries to fight bacterial and fungal infections. However, the molecular basis of these properties has not been fully covered. Considering that difficult-to-control infections are becoming a rising global problem, there is a need to elucidate the molecular potential of t-CA.

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10.1016/j.phymed.2024.155845

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