Kritin Mehrotra

Cygnus (United States)

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Dilip Kumar Macharla

Sunshine Hospitals

Sundeep Lakhtakia

Asian Institute of Gastroenterology

Raveena Miryala

The University of Texas Medical Branch at Galveston

Anuradha Sekaran

Asian Institute of Gastroenterology

Srivenu Itha

Cygnus (United States)

Nageshwar R. Duvvur

Asian Institute of Gastroenterology

Naveen Mehrotra

Sunshine Hospitals

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Asian Institute of Gastroenterology

Cygnus (United States)

Sunshine Hospitals

Krishna Institute of Medical Sciences

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Sanjay Gandhi Post Graduate Institute of Medical Sciences

The Japanese Society of Gastroenterological Surgery

Iwate Medical University

Onomichi General Hospital

Hiroshima University

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Endoscopic Ultrasound-Guided Radiofrequency Ablation of Metastatic Pancreatic VIPoma: A Novel Treatment

Cureus (2024)

Sundeep Lakhtakia Kritin Mehrotra Anuradha Sekaran Srivenu Itha Nageshwar R. Duvvur

VIPomas are a rare type of functional pancreatic neuroendocrine tumors (PNETs), causing symptoms due to their hypersecretion in the gastrointestinal tract. The rare association of PNETs with tumors of endocrine organs such as pituitary and parathyroid glands is called multiple endocrine neoplasia (MEN1) syndrome. Due to their indolent course, VIPomas often present late in the illness and may already have metastatic disease. The index case had MEN1 syndrome with biopsy-proven small sub-centimetric metastatic VIPoma and a history of parathyroidectomy for nodules in the past. The patient had a suspicion of pancreatic cholera and, after an appropriate workup, was treated by endoscopic ultrasound (EUS)-guided radiofrequency ablation (RFA) of the metastatic pancreatic VIPomas. EUS-guided RFA is a procedure by which the lesions are viewed under endoscopic ultrasound and undergo coagulative necrosis due to the high temperatures the tissue is subjected to. The application of EUS-guided radiofrequency ablation for sub-centimetric metastatic pancreatic VIPoma as a daycare procedure can be a valuable tool in its management.

Endoscopic Ultrasound

Coagulative necrosis

10.7759/cureus.67114

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A rare case of spinal extradural teratoma with mediastinal extension

Journal of Pediatric Neurosciences (2023)

Dilip Kumar Macharla Raveena Miryala Kritin Mehrotra Naveen Mehrotra

A bstract Introduction: Spinal extradural teratomas extending to posterior mediastinum are very rare and seldom reported. Case Report: A 4-year-old boy presented with progressive spastic paraparesis with sphincteric dysfunction was misdiagnosed as cerebral palsy. His magnetic resonance imaging showed D2-D5 extradural tumor, extending to the posterior mediastinum, causing severe thecal sac compression. Intraspinal part of the tumor was excised, and the child made a good recovery after the surgery. On histopathological examination, it was confirmed as a mature cystic teratoma. Conclusion: Spinal tumors with myelopathy may mimic cerebral palsy in children. To the authors’ knowledge, there are very few reported cases of spinal teratomas extending to the mediastinum.

10.4103/jpn.jpn_164_21

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