The purpose of this study was to evaluate the predictors of target lesion revascularization (TLR) after Paclitaxel-eluting stent (PES) implantation in three hundred twenty nine lesions of 250 patients with coronary artery disease. All pre- and post-procedural images were analyzed using a CMS-GFT system (MEDIS, The Netherlands). The incidence of insulin-treated diabetes mellitus was significantly higher in the TLR group than in the non-TLR group (15.9% vs. 4.17%, p=0.03). The lesion length was longer and the reference diameter was smaller in the TLR group than in the non-TLR group (19.8±11.3 mm vs. 15.3±8.1 mm, p=0.03, 2.48±0.47 mm vs. 2.88±0.6mm, p=0.01, respectively). The incidence of severe calcification was higher in the TLR group than in the non-TLR group (33.3% vs. 8.3%, p=0.027). A multivariate analysis showed that stent length and calcification were strong predictors of TLR after PES implantation in this study ; stent length was associated with a 1.3- to 14.4-fold higher relative risk of TLR, while patients with calcification were associated with a 2.0- to 26.5-fold higher risk of TLR relative to those without calcification.
