Latifa Henaoui

University of Abou Bekr Belkaïd

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i-10 index

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Co-Authors

Salim Benkhedda

University of Algiers Benyoucef Benkhedda

Nabila Taleb Bendiab

University of Abou Bekr Belkaïd

Omar Aït Mokhtar

Collaborative Group (United States)

Atif Merad

University of Abou Bekr Belkaïd

D. Regagba

London School of Hygiene & Tropical Medicine

Mohamed Arezki

University of Blida

Zahira Barka Bedrane

University of Abou Bekr Belkaïd

Djaouad Bouchenak Khelladi

University of Abou Bekr Belkaïd

Souhila Ouabdesselam

Collaborative Group (United States)

A. Meziane Tani

University of Abou Bekr Belkaïd

Cooperative Institutions

University of Abou Bekr Belkaïd

University of Algiers Benyoucef Benkhedda

Hôpital Mustapha Pacha

Collaborative Group (United States)

Université Toulouse III - Paul Sabatier

Collaborative Research Group

University of Sciences and Technology Houari Boumediene

University of Science and Technology

Korea University of Science and Technology

Marie Curie

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THE TRIGLYCERIDE- GLUCOSE INDEX: AN INDEPENDENT FACTOR OF A SUBCLINICAL LEFT VENTRICULAR DYSFUNCTION IN TREATED HYPERTENSIVE PATIENTS

Journal of Hypertension (2022)

Souhila Ouabdesselam Omar Aït Mokhtar Nabila Taleb Bendiab Latifa Henaoui Salim Benkhedda

The triglyceride-glucose (TyG) index is known to be a simple surrogate marker of insulin resistance. The aim of this study was to investigate association between the TyG index and the two- dimensional longitudinal left vetricular global strain in treated hypertensive patients.A total of 75 treated hypertensive patients were enrolled in this study. Anthropometric and cardiovascular risk factors were measured. The TyG index was calculated as ln[fasting triglycerides (mg/dl) × fasting glucose(mg/dl)/2]. The two- dimensional longitudinal left vetricular global strain where evaluated and express in absolute value. Others echocardiographic parameters where mesured: E/E', left atrial volume and biological parameters: Total cholesterol, HDL cholesterol, LDL cholesterol and glomerular filtartion. Multivariable linear regression analysis was performed to identify the associations between this parameters.Multivariable linear regression analysis showed that a higher TyG index was associated with lower global longitudinal LV strain (p = 0,04), higher body mass index (p = 0,000), higher E/E' (p = 0,009) and lowest glomerular filtration rate (p = 0,001).A high TyG index was significantly associated with a low global longitudinal LV strain. The results suggest that the TyG index, as a simple indicator of insulin resistance, may reflect subclinical cardiac dysfunction.

Subclinical infection

Mass index

10.1097/01.hjh.0000837920.43685.38

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HYPERTENSIVE HEART DISEASE, WHAT ARE THE FACTORS PRECIPITATING ITS EARLY ONSET?

Journal of Hypertension (2022)

Nabila Taleb Bendiab Latifa Henaoui Salim Benkhedda

Hypertension is a well-established risk factor for cardiovascular disease. It causes left ventricular pressure overload, and changes in cardiac geometry and LV hypertrophy.This study is intended to assess the clinical and echocardiographic factors associated with and predictive for early impairment of left ventricular function as assessed using global longitudinal strain evaluation in hypertensive patients.Cross-sectional descriptive study, with a total number of 130 hypertensive and with the objective of evaluating the study of longitudinal function by 2D strain in patients with systemic hypertension with preserved LVEF and the determination of predictors the decrease GLS in this population. This work is to make a complete study echo cardiographic, including LVEF biplane Simpson method, calculation of left ventricular mass indexed and relative parietal thickness, analysis diastolic function and the study of longitudinal strain of the LV by the speckle tracking technique (calculation of GLS).The prevalence of left ventricular hypertrophy (LVH) was found in (66%). half of the patients (49%) presented a concentric hypertrophy, It was clearly noted that 73%of the patients had a relative wall thickness (RWT)> 0.42. Alterations in diastolic function were detected in 89% of the group, 18% had severe diastolic dysfunction with elevation in filling pressure. Analysis of the longitudinal systolic function of the left ventricle took the average GLS as a reference value. The mean GLS was found to be -16.9 ± 3.2%, within a range between -25% and-11.6%.Low GLS values (>-17%) were found in 45.5%. In particular, 34.4% of the patients had no left ventricular hypertrophy (LVH) and 50.7% of them presented LVH.The average systolic and diastolic blood pressures, taken at the time of echocardiographic analysis, were found higher in the subgroup of hypertensive patients with low GLS.Statistical analysis revealed significant correlation between the decrease in GLS and diabetes the values of blood pressure and elevated filling pressures.The evaluation of longitudinal systolic function by 2D strain provides new insight of myocardial function in hypertension that could improve the pathophysiological understanding and identify high-risk heart failure patients eligible for preventive strategies.

Concentric hypertrophy

Hypertensive heart disease

Speckle tracking echocardiography

Pressure overload

10.1097/01.hjh.0000837904.90323.c3

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The Impact of Uncontrolled Hypertension on the Longitudinal Systolic Function of the Left Ventricle

Current Hypertension Reviews (2021)

Nabila Soufi Taleb Bendiab Salim Benkhedda Latifa Henaoui A. Meziane Tani

Background: The assessment of the longitudinal component of left ventricular (LV) function is of major clinical importance for the early detection of LV contractile impairment. The aim of this study was to determine the impact of uncontrolled hypertension, on LV longitudinal systolic performance. Methods: The study population included 400 hypertensive patients: 271 patients with uncontrolled blood pressure (BP) and 112 without controlled BP, all patients underwent a complete ultrasound evaluation with the calculation of the LV mass, evaluation of diastolic function as well as longitudinal systolic function. Results: Conventional echo demonstrated that uncontrolled patients had increased LV mass (P 0.007), LA (left auricular) dimension (P 0.004), left ventricular wall thickness and impairment of diastolic function (E/E’6 ± 2.1 vs 7.4 ±3.0 P=0.001) while no affection of systolic function could be detected. By deformation imaging, there was a reduction in longitudinal strain (apical 4 view -16.2 ±2.9 vs -18.2± 2.6 P 0.02, apical 3 view -17.3 ± 3.3 vs. -18.9 ± 4.1 P 0.01). Similarly, systolic strain rate (SRsys) and early diastolic SR (SRe) reduced significantly in longitudinal direction. Conclusion: Although EF was not different between uncontrolled patients and controls, LV longitudinal strain and strain rate by 2D speckle tracking were lower in the uncontrolled group.

Longitudinal Study

Speckle tracking echocardiography

Systole

10.2174/1573402117666210218105338

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Facteurs prédictifs d’évolution vers un handicap important au cours de la sclérose en plaques dans la région de Tlemcen

Revue Neurologique (2016)

Zahira Barka Bedrane Atif Merad Latifa Henaoui D. Regagba Mohamed Senoussaoui

10.1016/j.neurol.2016.01.216

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