Lilian Sung

Hospital for Sick Children

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Andrés Gómez‐De León

Universidad Autónoma de Nuevo León

Luz Tarín‐Arzaga

Universidad Autónoma de Nuevo León

L. Anderson

National Renewable Energy Laboratory

Yigal Dror

University of Toronto

ÁM

Ákos Moravánszky

ETH Zurich

Melvin H. Freedman

University of Toronto

David Gómez‐Almaguer

Hospital Universitario Dr José Eleuterio Gonzalez

Ed Eigen

Ian Thornley

Harvard University

José Carlos Jaime‐Pérez

Universidad Autónoma de Nuevo León

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Universidad Autónoma de Nuevo León

Hospital Universitario Dr José Eleuterio Gonzalez

Instituto Nacional de Neurología y Neurocirugía

University of Toronto

Hospital for Sick Children

SickKids Foundation

Royal Manchester Children's Hospital

University College London

Great Ormond Street Hospital

Medicina

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Abnormal telomere shortening in leucocytes of children with Shwachman–Diamond syndrome

British Journal of Haematology (2002)

Ian Thornley Yigal Dror Lilian Sung Robert Wynn Melvin H. Freedman

Summary. Haemopoietic dysfunction, ranging from single‐lineage cytopenia to severe aplasia and/or myelodysplasia (MDS), is prominent in Shwachman–Diamond syndrome (SDS). To assess haemopoietic stem cell proliferation in SDS, we compared leucocyte telomere length in 12 patients with SDS to that of 41 controls, using an in‐gel hybridization technique. SDS patients had an age‐adjusted mean telomere length 1·4 kilobase pairs (kbp) shorter than controls ( P < 0·0001). Patients with'non‐severe′ SDS (one‐ or two‐lineage cytopenias; no MDS) had shortened telomeres (−1·4 kbp; P = 0·0004), as did those with ‘severe’ SDS. We conclude that stem cell hyperproliferation is a feature of SDS from its outset.

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10.1046/j.1365-2141.2002.03371.x

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Contributions to the American Society of Hematology Meeting From Low- and Middle-Income Countries: An In-Depth Analysis and Call to Action

JCO Global Oncology (2021)

Andrés Gómez‐De León Perla R. Colunga‐Pedraza Luz Tarín‐Arzaga Emmanuel Bugarín-Estrada Lilian Sung

Establishing research capacity in low- and middle-income countries (LMICs) is key for improving the outcomes of patients with hematologic diseases globally. Few studies have analyzed the contributions of LMICs to global hematology. The American Society of Hematology Meeting (ASH) is the largest international academic event where peer-reviewed contributions in our field are presented.

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10.1200/go.20.00600

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Thresholds Number 5: March 9 1993

Thresholds (1993)

Ed Eigen Ákos Moravánszky L. Anderson Renee Chow Lilian Sung

October 01 2019 Thresholds Number 5: March 9 1993 Ed Eigen, Ed Eigen Search for other works by this author on: This Site Google Scholar Akos Moravanszky, Akos Moravanszky Search for other works by this author on: This Site Google Scholar Lawrence Anderson, Lawrence Anderson Search for other works by this author on: This Site Google Scholar Renee Chow, Renee Chow Search for other works by this author on: This Site Google Scholar Lilian Sung Lilian Sung Search for other works by this author on: This Site Google Scholar Author and Article Information Ed Eigen Akos Moravanszky Lawrence Anderson Renee Chow Lilian Sung Online Issn: 2572-7338 Print Issn: 1091-711X © 1993 Massachusetts Institute of Technology1993Massachusetts Institute of Technology Thresholds (1993) (5): 1–6. https://doi.org/10.1162/thld_i_00632 Cite Icon Cite Permissions Share Icon Share Facebook Twitter LinkedIn MailTo Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Search Site Citation Ed Eigen, Akos Moravanszky, Lawrence Anderson, Renee Chow, Lilian Sung; Thresholds Number 5: March 9 1993. Thresholds 1993; (5): 1–6. doi: https://doi.org/10.1162/thld_i_00632 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsThresholds Search Advanced Search This content is only available as a PDF. © 1993 Massachusetts Institute of Technology1993Massachusetts Institute of Technology Article PDF first page preview Close Modal You do not currently have access to this content.

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10.1162/thld_i_00632

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