Yueying Lin

Kunming Medical University

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Da‐Li Sun

Kunming Medical University

Yunyun Cen

Kunming Medical University

Yu‐Xing Qi

Kunming Medical University

Yanbo Sun

Kunming Medical University

Pengyuan Xu

Kunming Medical University

Yijun Li

Wenzhou Medical University

Ting Yang

Imperial College London

Qingwen Xu

Guangdong Medical College

Weiming Li

Army Medical University

Wei‐Ming Li

Ministry of Health and Welfare

Cooperative Institutions

Kunming Medical University

Fujian Normal University

Chinese Academy of Sciences

Sun Yat-sen University

University of Chinese Academy of Sciences

Chongqing Medical University

Shanghai Jiao Tong University

Fujian Institute of Research on the Structure of Matter

Zhejiang University

Xiamen Institute of Rare-earth Materials

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Quality assessment of the guidelines for the management of malignant pleural effusions and ascites

World Journal of Surgical Oncology (2020)

Jiaxi Li Yanmei Shi Li‐Ya An Jinxu Yang Yu‐Xing Qi

Abstract Objectives To fully assess the quality of the guidelines for the management of malignant pleural effusions (MPE) and ascites and reveal the heterogeneity of recommendations and possible reasons among guidelines. Methods A systematic search was performed in the database to obtain guidelines for the management of MPE and ascites. The AGREE IIGtool was used to assess the quality of these guidelines. The Measurement Scale of Rate of Agreement (MSRA) was introduced to assess the scientific agreement of formulated recommendations for the management of MPE and ascites among guidelines, and evidence supporting these recommendations was extracted and analyzed. Results Nine guidelines were identified. Only 4 guidelines scored more than 60% and are worth recommending. Recommendations were also heterogeneous among guidelines for the management of MPE, and the main reasons were the different emphases of the recommendations for the treatment of MPE, the contradictions in recommendations, and the unreasonably cited evidence for MPE. Conclusions The quality of the management guidelines for patients with MPE and malignant ascites was highly variable. Specific improvement of the factors leading to the heterogeneity of recommendations will be a reasonable and effective way for developers to upgrade the recommendations in the guidelines for MPE.

Surgical oncology

10.1186/s12957-020-02097-y

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Citations (15)

The relationship between pistachio (Pistacia vera L) intake and adiposity

Medicine (2020)

Ke Xia Ting Yang Li‐Ya An Yueying Lin Yu‐Xing Qi

Abstract Background: The aim of the study was to conduct a systematic review to comprehensively evaluate the relationship between pistachio intake and obesity. Methods: We searched 6 databases and acquired parameters from randomized controlled trials regarding obesity, including body weight, body mass index (BMI), and waist circumference. A fixed-effect model was applied to the meta-analysis for the weighted mean difference (WMD) between a diet with pistachios and a control diet. Results: Eleven trials including a total of 1593 subjects met the inclusion criteria. Compared to the group on a control diet, the pistachio diet group showed lower BMI values (WMD: −0.18 kg/m 2 ; 95% confidence interval [CI]: −0.26, −0.11 kg/m 2 ; I 2 = 29.8%) and no differences in body weight (WMD: −0.22 kg; 95% CI: −0.50, 0.07 kg; I 2 = 0.0%) or waist circumference (WMD: 0.76 cm; 95% CI: −0.11, 1.63 cm; I 2 = 7.0%). Conclusion: A diet with pistachios reduced BMI and had no significant effects on body weight and waist circumference.

Pistacia

Circumference

Waist-to-height ratio

10.1097/md.0000000000021136

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Citations (13)

Stability of bovine serum albumin labelled by rhodamine B isothiocyanate

Biomedical Research-tokyo (2017)

Ting Yang Dali Sun Pengyuan Xu Shumin Li Yunyun Cen

The aim of this study was to label Bovine Serum Albumin (BSA) by Rhodamine B Isothiocyanate (RBITC) and test its stability in vivo. RBITC-BSA was labelled by the improved Marshall’s method, scanned at full wavelength, and the RBITC:BSA ratio was calculated. Blood and urine samples were obtained from rabbits injected with the RBITC-BSA complex and SDS-PAGE analysis was performed. Full wavelength scanning showed that the labelled RBITC-BSA complex possessed features of both RBITC and BSA, and the RBITC:BSA ratio was 1:80. Furthermore, the RBITC-BSA complex was stable in vivo. Thus, we developed a stable RBITC-BSA complex with high specificity and sensitivity, which could be used as a tracer molecule to study protein transportation and vascular permeability.

Bovine serum albumin

Rhodamine B

Serum Albumin

Fluorescein isothiocyanate

Rhodamine

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Citations (9)

閩南語童謠繪本《魚歌》創作論述

林玥穎 Yueying Lin

10.6814/nccu202101329

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Citations (0)

Quality evaluation of metabolic and bariatric surgical guidelines

Frontiers in Endocrinology (2023)

Zi-Han Qin Xin Yang Ya-Qi Zheng Li‐Ya An Ting Yang

To evaluate the quality of surgical guidelines on bariatric/metabolic surgery.Four independent reviewers used the AGREE II (The Appraisal of Guidelines for Research and Evaluation II) tool to assess the methodological quality of the included guidelines and conducted a comparative analysis of the main recommendations for surgical methods of these guidelines.Nine surgical guidelines were included in this study. Five articles with AGREE II scores over 60% are worthy of clinical recommendation. The field of rigor of development was relatively low, with an average score of 50.82%. Among 15 key recommendations and the corresponding best evidence in the guidelines, only 4 key recommendations were grade A recommendations.The quality of metabolic and bariatric guidelines is uneven, and there is much room for improvement.

Quality of evidence

10.3389/fendo.2023.1118564

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Citations (3)

miR-338-3p attenuates oxaliplatin resistance in gastric cancer cells via targeting thrombospondin-1

Archives of Medical Science (2020)

Yueying Lin Da‐Li Sun Qingwen Xu Yijun Li Yanbo Sun

Introduction Oxaliplatin resistance (OR) as a poor prognostic factor is closely associated with gastric cancer (GC) recurrence and metastasis. The present study aimed to explore the molecular mechanism underlying oxaliplatin-based chemotherapy resistance of GC. Material and methods Two acquired OR strains (BGC-823-OR and MGC-803-OR) were generated by long-term oxaliplatin induction. Cell viability, apoptosis, migration and invasion were evaluated using CCK-8, TUNEL staining and transwell assay, respectively. THBS1 as a direct target of miR-338-3p was validated using the bioinformatics algorithm and luciferase reporter assay. qRT-PCR and western blotting were used to measure gene and protein expression, respectively. Results miR-338-3p was significantly down-regulated, and THBS1 protein level was significantly up-regulated in BGC-823-OR and MGC-803-OR cells compared with parental cell lines. Overexpression of miR-338-3p elevated oxaliplatin sensitivity in BGC-823-OR and MGC-803-OR cells. In addition, we revealed that THBS1 was a direct target of miR-338-3p. Overexpression of miR-338-3p or silence of THBS1 inhibited growth, migration and invasion and promoted apoptosis in BGC-823-OR and MGC-803-OR cells. Conclusions miR-338-3p appeared to obtund oxaliplatin-based chemotherapy resistance of GC cells by repression of THBS1. The miR-338-3p/ THBS1 signaling axis might be a prospective therapeutic target to mitigate chemotherapy resistance in GC.

Viability assay

Thrombospondin 1

10.5114/aoms.2020.98039

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Citations (4)

Accuracy of using serum D-dimer for diagnosis of acute intestinal ischemia

Medicine (2017)

Da‐Li Sun Shumin Li Yunyun Cen Qingwen Xu Yijun Li

The purpose of this meta-analysis is to comprehensively assess the accuracy of serum D-dimer for the diagnosis of acute intestinal ischemia.Diagnostic studies of D-dimer for accurate diagnosis of acute intestinal ischemia were extracted from 6 databases, and prospective and retrospective studies that provided adequate data on sensitivity and specificity were included here. Sensitivity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were calculated. The overall diagnostic performance of D-dimer was assessed by plotting a summary receiver operating characteristic curve (SROC) and calculating the area under the curve (AUC).A total of 1300 patients with suspected acute intestinal ischemia from 12 studies met the inclusion criteria. The combined sensitivity, specificity, PLR, NLR, and DOR were 0.94 (95% CI: 0.87-0.97), 0.50 (95% CI: 0.40-0.61), 1.9 (95% CI: 1.5-2.3), 0.12 (95% CI: 0.05-0.26), and 16 (95% CI: 7-39), respectively. The AUC was 0.81 (95% CI: 0.78-0.84).The results of this meta-analysis suggested that plasma D-dimer detection might be a useful means of identifying patients with acute intestinal ischemia of the abdomen.

D-dimer

Intestinal Ischemia

10.1097/md.0000000000006380

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Citations (24)

Heterogeneity of nutrition care procedures in nutrition guidelines for cancer patients

Clinical Nutrition (2019)

Xiaohu Zhao Ting Yang Xudong Ma Yu‐Xing Qi Yueying Lin

Clinical nutrition

Critical appraisal

Evidence-Based Medicine

Medical nutrition therapy

10.1016/j.clnu.2019.08.022

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Citations (23)

The effect of transabdominal preperitoneal (TAPP) inguinal hernioplasty on chronic pain and quality of life of patients: mesh fixation versus non-fixation

Surgical Endoscopy (2017)

Weiming Li Da‐Li Sun Yanbo Sun Yunyun Cen Shumin Li

10.1007/s00464-017-5485-1

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Citations (20)

Fecal Microbiota Transplantation as a Novel Therapy for Ulcerative Colitis

Medicine (2016)

Da‐Li Sun Wei‐Ming Li Shumin Li Yunyun Cen Qingwen Xu

Variation in clinical evidence has prevented the adoption of fecal microbiota transplantation (FMT) in patients with ulcerative colitis (UC). We aimed to conduct a systematic review and meta-analysis to determine the efficacy and safety of FMT in UC. A systematic literature search was performed in 5 electronic databases from inception through September 2015. Inclusion criteria were reports of FMT in patients with UC. Studies were excluded if they did not report clinical outcomes or included patients with infections. Clinical remission (CR) was defined as the primary outcome. Eleven studies (2 randomized controlled trials (RCTs), 1 open-label case-control study, and 8 cohort studies) with a total of 133 UC patients were included in the analysis. In 11 studies (including 8 noncontrol cohort studies and the treatment arms of 3 clinical control trials), the pooled proportion of patients who achieved CR was 30.4% (95% CI 22.6–39.4%), with a low risk of heterogeneity (Cochran Q test, P = 0.139; I2 = 33%). A subgroup analysis suggested that no difference in CR was detected between upper gastrointestinal delivery versus lower gastrointestinal delivery. Furthermore, subgroup analysis revealed that there was no difference in CR between single infusion versus multiple infusions (>1) of FMT. All studies reported mild adverse events. FMT is potentially useful in UC disease management but better-designed RCTs are still required to confirm our findings before wide adoption of FMT is suggested. Additionally, basic guidelines are needed imminently to identify the right patient population and to standardize the process of FMT.

Subgroup analysis

10.1097/md.0000000000003765

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Citations (32)