856 Reviews one of recognition of features already having been shown tohave fed into themature work, and this is an approach which works extremelywell. Connon has chosen the theme of 'identity and transformation' not because of the rather obvious uses towhich theatre classically subjects such themes (for example, with stock techniques such as disguise, mistaken identity, recognition scenes), in which regard Piron is no exception, but because Piron's theatre carries a 'deeper exploration ofwhether the assumption of an alternative identity can have any pro found impact on who a character is, and, in certain cases, it is shown to lead to a deeper understanding of the individual's nature' (p. 173).More widely, what emerges from Connon's analyses is the sheer vitality of Piron's production, its sometimes 'anarchic' inventiveness (p. I73), and itspropensity toquestion hierarchies and cross boundaries of genre. For instance, his plots frequently play upon classic schemata only to frustrateor subvert expectations (see, forexample, discussion of L'Ecole des peres, pp. 34-40). Iwas also struck by the interesting discussion of Piron's aversion to contrived recognition scenes ingeneral, an aversion, Connon argues, he developed as a parodist of abuses of features such as this in the opera. Chapter 2 shows Piron's perhaps unintended pioneering role in the development of sensibility in the theatre (beforeNivelle de laChaussee and others), which with hindsight he disavowed inhis preface of 1758, the feature being one he ended up deploring. Equally interesting, though not foregrounded by the author, is theway inwhich the range ofPiron's plays might encourage us to thinkagain about thehierarchy of the theatres and the fluidity of the Paris theatricalworld at this time, given figures such as Piron who wrote for such a range of institutions, and in such differentgenres: this isdue partly to oppor tunism of thewriters themselves, of course; but italso points to theiradaptability and demonstrates the cross-fertilization between what used to be called 'high' and 'low' culture. For all of these reasons, I recommend thisbook highly. CHRIST'S COLLEGE, CAMBRIDGE MARK DARLOW Two French Libertine Novels: 'The Story of Madame de Luz' and 'The Confessions of theComte de ***'. By CHARLES PINOT-DuCLOS. Trans. with an introduction by DOUGLAS PARM#EE. (AMS Studies in theEighteenth Century, 46) New York: AMS Press. 2006. xxvi+ I92 pp. $64.50. ISBN 978-o-404-63546-6. Les livresphilosophiques, as theywere known in the book trade, flourished in eight eenth-century France, especially from the I740s, inwhich the new vogue forerotic works inprose was paralleled by a remarkable output of philosophical essays. In this decade alone there appeared a number of landmark works of the French Enlight enment, notablyMontesquieu's De l'Esprit des lois,La Mettrie's L'Homme machine, Buffon's Histoire naturelle, theProspectus for theEncyclopedie, and Rousseau's Dis cours sur les sciences et lesarts. It isno coincidence that an expansion inwritings that challenged social, moral, political, and religious as well as sexual norms should occur alongside that inEnlightenment philosophy, the principal architects ofwhich, such asDiderot and Voltaire, themselves wrote erotic works. Such was the case ofCharles Pinot-Duclos, whose best-known work, the Considerations sur lesmceurs (I75 i), a collection of essays on contemporary morality and behaviour, highly regarded at the time and widely read throughout Europe, offersa subtle critique of theFrench upper classes. This work was composed over a number of years, and commenced shortly afterDuclos wrote the two licentious tales in this attractively bound volume. These amusing and provocative stories firstappeared in I74I and I742 respectively, their publication riding the crest of the age's new wave ofwritings that challenged ortho doxies and poked fun at the hypocrisies and frivolities of court society.The longer MLR, I03.3,2oo8 857 of the two,The Confessions du Comte de ***, treats issues similar to those of the Considerations, but with greater concision and with considerably less gravity, though both prefer euphemism toobscenity, abounding inmischievous ironies and allusions, but always within a framework ofmoral values, if liberally conceived. It is replete with witty epigrammatical observations thatmay be favourably compared with La Rochefoucauld's maxims. Douglas Parmee's new translation of these excellent tales combines accuracy with elegance, and succeeds well inpreserving the playful...
Integrating Quality, Environmental, Health, and Safety Systems shows you how to take advantage of the similarities that exist between the three systems and how to integrate your quality, environmental, and health and safety activities into one efficient system. You'll discover how closely connected these standards actually are, and you'll get the checklists you need to implement the standards, including a checklist designed for use by your own internal auditors. Each standard gets its own comprehensive chapter where you'll find a detailed examination of the standard's elements, including what each required element means and how to conform with each of the requirements.
Phosphorylation of bovine chromaffin granules by ATP leads to the formation of diphosphoinositide in the granule membrane. Both phosphatidylinositol kinase and its substrate are components of this membrane, and triphosphoinositide is not formed under the conditions of the assay. The reaction is Mg(2+)-dependent and is stimulated by Mn(2+) and F(-) ions. The initial reaction is rapid, with a broad pH profile and a ;transition' temperature for its activation energy at 27 degrees C. The apparent K(m) for ATP is 5mum. ATP, N-ethylmaleimide, Cu(2+) ions and NaIO(4) are inhibitory. The phospholipids of chromaffin-granule membranes have been analysed: 6.8% of the lipid P is found in phosphatidylinositol, and only 2-3% in phosphatidylserine. Comparison of the rate of phosphorylation of intact and lysed granules suggests that the sites for phosphorylation are on the outer (cytoplasmic) surface of the granules, and diphosphoinositide may therefore make an important contribution to the charge of the chromaffin granule in vivo.
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