Constantin Crăciun

Babeș-Bolyai University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Lucian Barbu‐Tudoran

National Institute for Research and Development of Isotopic and Molecular Technologies

Adrian Florea

Iuliu Hațieganu University of Medicine and Pharmacy

Alina Elena Pârvu

Iuliu Hațieganu University of Medicine and Pharmacy

Mircea Tămaş

Iuliu Hațieganu University of Medicine and Pharmacy

Mihaela Corneanu

Univesity of Life Science "King Mihai I" from Timisoara

Marcel Pârvu

Babeș-Bolyai University

Gabriel Corneanu

Vallen Systeme (Germany)

Simion Aştilean

Babeș-Bolyai University

Gabriela Dogaru

Iuliu Hațieganu University of Medicine and Pharmacy

Viorel Soran

Vasile Goldis Western University of Arad

Cooperative Institutions

Iuliu Hațieganu University of Medicine and Pharmacy

Babeș-Bolyai University

Spitalul Clinic Județean de Urgență Cluj-Napoca

University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca

Vasile Goldis Western University of Arad

National Institute of Research and Development for Biological Sciences

Technical University of Cluj-Napoca

National Institute for Research and Development of Isotopic and Molecular Technologies

University of Oradea

Clinical Emergency Hospital Bucharest

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Antifungal Activities of Chelidonium majus Extract on Botrytis cinerea in vitro and Ultrastructural Changes in its Conidia

Journal of Phytopathology (2008)

Marcel Pârvu Alina Elena Pârvu Constantin Crăciun Lucian Barbu‐Tudoran Mircea Tămaş

Abstract The extract from the aboveground parts of Chelidonium majus reduced the mycelial growth of Botrytis cinerea on Czapek agar medium. In minimum fungicidal concentration (60 μ l/ml), the extract induced irreversible ultrastructural changes in B. cinerea conidia.

Chelidonium

10.1111/j.1439-0434.2008.01410.x

Cite

Citations (28)

Identification of new structural elements within ‘porosomes’ of the exocrine pancreas: A detailed study using high-resolution electron microscopy

Micron (2012)

Constantin Crăciun Lucian Barbu‐Tudoran

Secretory Vesicle

Organelle

Exocrine pancreas

10.1016/j.micron.2012.05.011

Cite

Citations (19)

Postembryonic ontogenetic development in Porcellio scaber(Crustacea: Isopoda)

Pedobiologia (1987)

NICOLAE TOMESCU Constantin Crăciun

Isopoda

10.1016/s0031-4056(23)00385-2

Cite

Citations (19)

Bee (Apis mellifera) Venom Produced Toxic Effects of Higher Amplitude in Rat Thoracic Aorta than in Skeletal Muscle—An Ultrastructural Study

Microscopy and Microanalysis (2012)

Adrian Florea Constantin Crăciun

Abstract In this study, changes produced in aorta and triceps surae muscle of Wistar rats as response to bee venom (BV) envenomation were analyzed by transmission electron microscopy and morphometry. A subchronic treatment of 30 days with daily doses of 700 μg BV/kg and an acute-lethal treatment with a single dose of 62 mg BV/kg were performed. The subchronic treatment resulted in endothelial cell retraction, a thicker subendothelial layer, and thinner elastic laminae and musculoelastic layers in aorta, and thicker endothelium and basal laminae in skeletal muscle. In both tissues polymorphous, swollen mitochondria with disrupted cristae were observed. The acute treatment produced extensive endothelial lesions, breakdown of the collagen layer and migration of muscle cells toward the intima in the aorta, and dilatation of endoplasmic reticulum in the skeletal muscle cells. Mitochondria were almost devoid of cristae or with few circular cristae in the smooth muscle cells while most of the mitochondria presented abnormal circular cristae in the skeletal muscle cells. Degenerative alterations in the aorta were of higher intensity in our experiments—both the intima and media strongly responded to BV, in contrast to those found at the level of the skeletal muscle cells where a moderate degenerative myopathy was recorded.

Thoracic aorta

Triceps surae muscle

10.1017/s1431927611012876

Cite

Citations (9)

Fenugreek powder exerts protective effects on alcoholised rats' kidney, highlighted using ultrastructural studies.

PubMed (2015)

George Ciprian Pribac Mircea Florin Sferdian Carmen Neamţu Constantin Crăciun C Roşioru

Trigonella foenum-graecum (TFG) seeds exert a protective antioxidant effect and membrane protector through their rich content in polyphenolic flavonoids. The previous research focused on the hypoglycemic action of the seeds, with scarce studies on the preventive effects in the pathology of the kidney. Our work was conducted on an experimental in vivo model; the animals were given two different concentrations of TFG seeds, consequently to alcohol intoxication. Transmission electron microscopy (TEM) analysis showed vacuolation in cytoplasm, edemas at the apical pole of the nephrocytes, diffusion of the cytoplasmic and mitochondrial matrix and the increase in number of the lysozymes and especially peroxisomes, as well as the congestion of blood capillaries. In the case of the groups T5R and T10R, which received Trigonella powder together with ethanol, the structural and ultrastructural changes produced by the ethylic intoxication were more reduced, being somewhat improved in the T5R group. Therefore, the majority of the cells nuclei have retained their spherical shape, being at the same time predominantly euchromatic, with little heterochromatin and evenly dispersed. Our results suggest the use of Trigonella seeds as a food supplement to prevent cellular deterioration and improve renal morphology and function.

Trigonella

Lipid droplet

Phytotherapy

Source

Cite

Citations (9)

Low temperature induced ultrastructural alterations in tomato ( Lycopersicon esculentum Mill.) shoot apex cells

Scientia Horticulturae (2017)

Adela Halmágyi Ana Coste Septimiu Tripon Constantin Crăciun

Plasmolysis

Tunica

Lycopersicon

Apex (geometry)

Fragmentation

Plant cell

10.1016/j.scienta.2017.04.019

Cite

Citations (12)

Ultrastructure and Development of Anthracoidea Elynae Ustilospores

DOAJ (DOAJ: Directory of Open Access Journals) (2009)

Marcel Pârvu Alina Elena Pârvu Constantin Crăciun Lucian Barbu‐Tudoran Mihai Pușcaș

The aim of the study was to examine the ultrastructure of Anthracoidea elynae ustilospores isolated from Kobresia myosuroides (Vill.) Fiori plant ovaries, harvested in the Bucegi Mountains, Romania. Samples examination was performed using scanning (SEM) and transmission (TEM) electron microscopy. The results showed that A. elynae ustilospores had a dynamic ultrastructure, because their three-layered cell wall, nucleus shape, lipid and glycogen accumulations in the cytoplasm changed at each developmental stage. In conclusion, according to the ultrastructural changes, A. elynae ustilospores development may be divided into three stages.

10.15835/nbha3713092

Cite

Citations (1)

Ultrastructural investigations of nuclear formations in carnation cells from cultured tissues.

CYTOLOGIA (1984)

Constantin Crăciun Dorina Cachia-Cosma Viorel Saran

Electron microscopic investigations on the cells obtained from tissue cultures of carnation (Dianthus caryophyllus var. Linda), have demonstrated the presence of two types of particular formations in the nucleus: a) electrondense loose bodies, composed of fibrillary structures; b) unelectrondense spherical-oval areas, with a slightly expressed structure. The possible connection of these structures with the nucleolus and nucleus-membrane functions, as well as their role in the rRNA synthesis and in the transfer processes through nucleus and cytoplasm, are discussed.

Dianthus

10.1508/cytologia.49.489

Cite

Citations (1)

Ultrastructural Aspects of Photoautotrophic Chrysanthemum Culture

Springer eBooks (1998)

V. Cristea Francesca Dalla Vecchia Constantin Crăciun Nicoletta La Rocca

Aseptic processing

Carbon source

10.1007/978-94-011-3953-3_969

Cite

Citations (3)

Premature termination of hair follicle morphogenesis and accelerated hair follicle cycling in Iasi congenital atrichia (fz^ica) mice points to fuzzy as a key element of hair cycle control

Experimental Dermatology (2005)

Lars Mecklenburg Desmond J. Tobin Marius V. Cirlan Constantin Crăciun Ralf Paus

Abstract: Inbred laboratory mice have proven to be useful model systems for studying hair biology and pathomechanisms of hair loss. Fuzzy ( fz ) is an autosomal recessive mutation that results in hair coat abnormalities. Though this mutant has long been known, its cutaneous abnormalities still await systematic analysis. Here, we provide a systematic skin phenotype analysis of mice that are homozygous for Iasi congenital atrichia (fz ica /fz ica ), which is allelic to fz . Homozygous mice exhibit a sparse hair coat after birth and completely loose their hair at around postnatal day 120. Although early and mid stages of hair follicle morphogenesis are normal, late hair follicle morphogenesis reveals multifocal cell degeneration within the Huxley layer of the inner root sheath (IRS) and a complete lack of the hair shaft medulla. In addition, hair follicle development is prematurely terminated by induction of the first postnatal hair cycle with premature entry into catagen. Subsequently, a dramatically shortened telogen is immediately followed by premature anagen development, resulting in a marked, generalized acceleration of hair follicle cycling. This suggests that fuzzy is not only involved in structural hair shaft integrity and differentiation of the IRS and medulla, but also plays an important role in the control of hair follicle cycling. Our data show that fuzzy is involved in controlling both catagen and anagen initiation, designating fuzzy an exciting target for characterizing the intracutaneous oscillator system that drives hair follicle cycling.

Hair cycle

Inner root sheath

Coat

Cabello

Medulla

Black hair

10.1111/j.0906-6705.2005.00343.x

Cite

Citations (20)