Thirty-eight eyes of 22 patients with corneal endothelial guttata were examined by slit lamp, tonometry, tonography, and wide-field specular microscopy. The mean value for facility of outflow (C55) was 0.23, and it was not statistically different from reported values for a normal population. Also, there was no correlation between extent of guttata as seen with wide-field specular microscopy and facility of outflow. Thus, contrary to a previous report, endothelial guttata does not seem to predispose to impaired facility of outflow.
• A total of 149 eyes with retinoblastomas were examined histopathologically to determine the types and frequencies of mechanisms inducing glaucoma. The most common mechanism was iris neovascularization with secondary peripheral anterior synechiae formation. In such cases, the tumor was almost always located at the posterior pole with involvement of central retinal vessels and with growth of a highly vascularized tumor mass into the vitreous. The second most common mechanism was massive exudative retinal detachment causing pupillary block and angle closure. In such cases, tumor growth was present within and under the retina. The third most common mechanism was a combination of the aforementioned mechanisms. Uveitis and/or necrotic tumor tissue in the anterior chamber as the sole mechanism inducing glaucoma was infrequently seen.
Trip-chaining behavior has generally been associated with various demographic characteristics of households and individuals. This includes households with children having more complex activity patterns, or those who are employed needing to conduct activities on the way to and from work because of time constraints. No studies, as yet, have controlled for other factors that might influence trip chaining behaviour, such as levels of urbanization, public transport availability, use of other transport modes, or various other local environmental factors. This paper explores these issues using both the 1995 Nationwide Personal Transportation Survey and the 2001 National Household Travel Survey. Both surveys have data on trip chaining behavior that allows multivariate analysis of individual level behavior. Various choice models are estimated, including ordered models that account for the number of chains in a trip. Results for both the 1995 and 2001 surveys are presented to examine potential changes in behavior over time.
Major investments in highway or transit infrastructure often require a decade or more to move from planning to completion. Therefore, a solid understanding of California's future transportation infrastructure needs implies a critical evaluation of the projections of the state's total population, what this population will look like, where they will live and work, their lifestyle choices, and most importantly, the combined impact of these factors on travel demand. Additionally, any serious evaluation of the future must consider the impact of technology, how it may change travel patterns and how it may be used as a tool for improving the effectiveness of transportation infrastructure. The following is the first in a series of working papers that will explore precisely this set of issues.Â
The present work relates to the implementation of core parallel architecture in a deep learning algorithm. At present, deep learning technology forms the main interdisciplinary basis of healthcare, hospital hygiene, biological and medicine. This work establishes a baseline range by training hyperparameter space, which could be support images, and sound with further develop a parallel architectural model using multiple inputs with and without the patient’s involvement. The chest X-ray images input could form the model architecture include variables for the number of nodes in each layer and dropout rate. Fourier transformation Mel-spectrogram images with the correct pixel range use to covert sound acceptance at the convolutional neural network in embarrassingly parallel sequences. COVIDNet the end user tool has to input a chest X-ray image and a cough audio file which could be a natural cough or a forced cough. Three binary classification models (COVID-19 CXR, non-COVID-19 CXR, COVID-19 cough) were trained. The COVID-19 CXR model classifies between healthy lungs and the COVID-19 model meanwhile the non-COVID-19 CXR model classifies between non-COVID-19 pneumonia and healthy lungs. The COVID-19 CXR model has an accuracy of 95% which was trained using 1681 COVID-19 positive images and 10,895 healthy lungs images, meanwhile, the non-COVID-19 CXR model has an accuracy of 91% which was trained using 7478 non-COVID-19 pneumonia positive images and 10,895 healthy lungs. The reason why all the models are binary classification is due to the lack of available data since medical image datasets are usually highly imbalanced and the cost of obtaining them are very pricey and time-consuming. Therefore, data augmentation was performed on the medical images datasets that were used. Effects of parallel architecture and optimization to improve on design were investigated.
Electronic Media Drs Wand, Shields, and Ritch have prepared a videotape that gives an overview of argon laser trabeculoplasty and iridectomy. Dr Shields discusses the indications, techniques, and results of laser trabeculoplasty. He reviews pertinent anatomic features of the angle, and notes variations of angle appearance to demonstrate potential sources of confusion to the laser surgeon. The technique of performing the proce"... clinically relevant facts regarding argon laser trabeculoplasty and iridectomy." dure is described in enough detail to provide a good review for the laser surgeon. Dr Shields' discussion includes practical hints such as using iridoplasty (gonioplasty) as an adjunctive technique in making angle structures more easily visible and, thereby, facilitating application of laser burns on the trabecular meshwork. The importance of treating the angle in divided sessions to prevent posttreatment intraocular pressure elevation is mentioned. The need to adjust the power level, depending on the degree of pigmentation of
• A randomized, double-blind clinical study was conducted on patients with primary open angle glaucoma to determine whether timolol and epinephrine have an additive effect in lowering intraocular pressure. Sixteen patients were randomly assigned to one of two treatment sequences (timolol alone, supplemented after two weeks with epinephrine, and vice versa). An initial additive effect in lowering IOP was found in both sequences. However, after several weeks of combined therapy, complete loss of additive effect was found. Patients who were treated first with epinephrine for two weeks and then supplemented with timolol had significantly lower IOPs, for at least two weeks, than patients in the reverse treatment sequence. Epinephrine treatment alone caused a significant increase in facility of outflow, but this effect did not occur with simultaneous timolol treatment. The results are discussed in terms of possible fundamental β- and α-adrenergic influences on aqueous dynamics and their potential clinical relevance.
