This communication reports the complete amino acid sequence (263 amino acids) for the insulin-like growth factor binding protein 1 in the bovine (bIGFBP-1). It is 70% homologous with the equivalent IGFBP-1 in human and rat.

Cloning (programming)

10.3109/10425179109020798

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Citations (11)

Use of bovine leukemia virus proviral DNA probes for the analysis of BLV-induced leukemogenesis

Richard Kettmann Luc Willems Claudine Bruck D. Grégoire Anneloes van den Broek

Bovine leukemia virus

Provirus

Source

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Citations (0)

Involvement of the cyclic AMP-responsive element binding protein in bovine leukemia virus expression in vivo

Journal of Virology (1994)

Emmanuelle Adam Pierre Kerkhofs M. Mammerickx R. Kettmann A. Burny

The TAR element (Tax-responsive element; also called TxRE) is a major determinant of the regulation of bovine leukemia virus (BLV) expression. In order to gain insight into the mechanisms of viral expression, complexes formed between proteins and the TAR enhancer DNA were analyzed by gel retardation assays. We report here that nuclear lysates from ex vivo-isolated B lymphocytes contain proteins that specifically bind to TAR. An antibody directed toward the cyclic AMP-responsive element binding (CREB) protein supershifted a complex (C1) present only in BLV-infected B lymphocytes. The CREB protein thus appears to be a major transcription factor involved in BLV expression in vivo.

Bovine leukemia virus

Transcription

10.1128/jvi.68.9.5845-5853.1994

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Citations (51)

Genomic Integration of Bovine Leukemia Provirus and Lack of Viral RNA Expression in the Target Cells of Cattle with Different Responses to BLV Infection

Hämatologie und Bluttransfusion (1981)

R. Kettmann G. Marbaix M. Mammerickx A. Burny

Bovine leukemia virus

Provirus

Lymphocytosis

Enzootic

Asymptomatic carrier

Deltaretrovirus

10.1007/978-3-642-67984-1_91

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Citations (4)