The design, synthesis, and bioevaluation of fluorescence- and biotin-labeled CXCR4 antagonists are described. The modification of D-Lys8 at an epsilon-amino group in the peptide antagonist Ac-TZ14011 derived from polyphemusin II had no significant influence on the potent binding of the peptide to the CXCR4 receptor. The application of the labeled peptides in flow cytometry and confocal microscopy studies demonstrated the selectivity of their binding to the CXCR4 receptor, but not to CXCR7, which was recently reported to be another receptor for stromal cell-derived factor 1 (SDF-1)/CXCL12.

10.1002/cbic.200700761

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Citations (39)

ChemInform Abstract: One‐Pot Synthesis of Carbazoles by Palladium‐Catalyzed N‐Arylation and Oxidative Coupling.

ChemInform (2008)

Toshiaki Watanabe Satoshi Ueda Shinsuke Inuki Shinya Oishi Nobutaka Fujii

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.200811115

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Citations (1)

Histochemical Studies on the Disorder of Muscle:Report 2. Phosphorylase, Succinic Dehydrogenase and Cholinesterase Activity in the Dystrophy-like Muscle after Cervical Sympathetic Ganglionectomy

Proceedings of the Japanese Histochemical Association (1963)

M Uono Hitoshi Tanabe Satoshi Ueda Masanori Tomonaga Osamu Wada

Ganglionectomy

Cholinesterase

Succinic dehydrogenase

Dystrophy

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Citations (1)

Cooperative Vehicle Highway Systems

Jacques Ehrlich Jeremy Millar Satoshi Ueda

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Outcome of STA-MCA anastomosis. Indications based on the cerebral hemodynamics.

Nosotchu (1998)

Hiroshi Tenjin Yoshio Ohmori Yoshio Imahori Satoshi Ueda Kenji Nakajima

脳血流量,脳循環予備能及び全身状態に考慮したSTA-MCA anastomosisの適応を論じる.国際共同研究の基準に年齢,脳血流量(CBF),脳循環予備能(oxygen extraction fraction)を追加した基準は定め,その基準を満たした6例のSTA-MCA anastomosis症例の周術期合併症,脳循環諸量の変化,脳虚血性続発症を検討した.その結果,全例で周術期合併症を認めなかった.脳循環諸量は改善する傾向にあった.全例で脳虚血性続発症を認めなかった.手術適応を決定するにあたり,患者の年齢,全身合併症,脳血流量,脳循環予備能を考慮にいれるならば,本術式が脳梗塞の予防に寄与する可能性が得られた.

10.3995/jstroke.20.351

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メキシコ新興自動車クラスターと内陸マキラドーラの発展 ; メキシコシンコウジドウシャクラスタートナイリクマキラドーラノハッテン ; Development of the new automotive cluster and the interior maquiladora in Mexico

慧. 上田サトシウエダ Satoshi Ueda

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Positron Emission Tomographic Measurement of Acute Hemodynamic Changes in Primate Middle Cerebral Artery Occlusion

Neurologia medico-chirurgica (1992)

Hiroshi Tenjin Satoshi Ueda Norihiko Mizukawa Yoshio Imahori Akihiko HINO

Specific hemodynamic changes in acute ischemia were investigated using a middle cerebral artery occlusion primate model and positron emission tomography. The cerebral blood flow (CBF), cerebral blood volume, oxygen extraction fraction (OEF), and cerebral metabolic rate for oxygen were measured 1, 3, and 9 hours after occlusion. OEF showed an increase in ischemic areas, and especially where CBF was below 18 ml/100 gm/min 1 hour after occlusion the OEF increased significantly (0.69 +/- 0.20, p < 0.05). Nine hours after occlusion, the OEF values were lower compared to those 1 and 3 hours after occlusion. Areas where CBF ranged from 18 to 31 ml/100 gm/min showed an increase in OEF at all times (p < 0.05). Clearly, OEF changes remarkably in the acute stage.

10.2176/nmc.32.805

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Citations (19)

The analysis of the course of motor impairment in fukuyama type congenital muscular dystrophy.

The Japanese Journal of Rehabilitation Medicine (1985)

Yayoi Okawa Satoshi Ueda Fumio Eto Nobuko Kikuchi

福山型先天性筋ジストロフィー症(広義)67例の運動障害の経過について検討し,以下の結果を得た.(1) 本症の運動障害の評価法である「運動機能レベル」に“レベル0:首の坐り不能”を追加した.(2) 運動機能の発達速度と最高到達レベルから歩行可能群,中間群,運動発達不良群(重症群)にグループ分けできた.(3) 最高到達レベルが高い程,到達する時期は遅い.(4) 歩行可能性などに男女差が認められ,本症の表現型の発現に際し,性差の関与が考えられる.(5) 先に行った最高到達レベル予測の試みを一部修正補足した。

Congenital muscular dystrophy

10.2490/jjrm1963.22.197

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Citations (2)