Mouse embryo fibroblast cells infected with M. arginini or M. hyorhinis showed a decreased ability to produce interferon and achieve the antiviral state following exposure to a synthetic polynucleotide, poly I·C. This effect by the mycoplasmas was reversed by the addition of DEAE-dx but not by neomycin, suggesting a mechanism of action of DEAE-dx not shared by neomycin. WI-38 cells infected with M. arginini also showed a decreased ability to respond to poly I·C.

Neomycin

Polynucleotide

10.3181/00379727-139-36374

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Citations (7)

Outbreak of Gram-negative septicaemia caused by contaminated continuous infusions prepared in a non-clinical area

Journal of Hospital Infection (1997)

Rebecca Koerner S. Morgan M. Ford K.E. Orr Janet M. McComb

Cross infection

Rapid response team

10.1016/s0195-6701(97)90055-4

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Citations (16)

Evaluation of cyclohexenoesculetin-beta-D-galactoside and 8-hydroxyquinoline-beta-D-galactoside as substrates for the detection of beta-galactosidase

Applied and Environmental Microbiology (1996)

Arthur L. James John D. Perry M. Ford Lyle Armstrong F.K. Gould

We describe the synthesis of two new substrates for the detection of beta-galactosidase and evaluate their performance in comparison with that of 5-bromo-4-chloro-3-indolyl-beta-D-galactopyranoside (X-Gal). Of 171 Enterobacteriaceae strains that were able to hydrolyze X-Gal, 166 (97.1%) also hydrolyzed cyclohexenoesculetin-beta-D-galactoside whereas only 96 (56.1%) showed evidence of hydrolysis of 8-hydroxyquinoline-beta-D-galactoside. No false-positive results were observed with either substrate.

Galactosides

BETA (programming language)

Galactosidases

10.1128/aem.62.10.3868-3870.1996

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Citations (30)

Note : Cyclohexenoesculetin‐β‐ D ‐glucoside: a new substrate for the detection of bacterial β‐ D ‐glucosidase

Journal of Applied Microbiology (1997)

Arthur L. James John D. Perry M. Ford Lyle Armstrong F.K. Gould

A new substrate for the detection of bacterial β-D-glucosidase was evaluated as an alternative to aesculin. This substrate, 3,4-cyclohexenoesculetin-7-β-D-glucoside, was compared with aesculin for the detection of β-D-glucosidase in 150 enterococci, 40 streptococci, 12 Listeria sp. and 250 strains of Enterobacteriaceae. In the Gram-positive strains tested, aesculin hydrolysis correlated with hydrolysis of 3,4-cyclohexenoesculetin-7-β-D-glucoside. In the Gram-negative strains the new substrate was hydrolysed by all aesculin-positive strains and also by four strains (10%) of Escherichia coli which gave a negative aesculin reaction. 3,4-Cyclohexenoesculetin-7-β-D-glucoside was shown to be a reliable alternative to aesculin and was shown to have significant advantages over aesculin when incorporated into solid media. This was due to the non-diffusible end product produced by hydrolysis of 3,4-cyclohexenoesculetin-7-β-D-glucoside in the presence of iron.

Glucoside

10.1046/j.1365-2672.1997.00370.x

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Citations (20)

Urinary Excretion of Tritium following Exposure of Man to HTO - a Two Exponential Model

Physics in Medicine and Biology (1968)

Wayne Snyder B. Fish S.R. Bernard M. Ford J. R. Muir

Data on urinary excretion of tritium by a 41-year-old male who accidentally inhaled (or ingested) tritium, presumed to be in the form of HTO, are presented along with an interpretation of these data and an estimate of the radiation dose delivered to tissues. Measurements of levels in urine were made as long as 255 days after the intake of the tritium. The data could be represented as a sum of two exponential terms, one with a half-life of about 9 days, the other of about 34 days. The total dose to body water was estimated to be about 16 rem, the long-term exponential contributing about 2% of the total. A two-compartment model was applied to the data. Equations were derived for the amounts of tritium in each compartment, and an estimate was obtained for the total dose in any tissue, based on a comparison with the content of hydrogen in the tissue. This method of estimating the dose may be applicable for other radionuclides and compounds. It assumes the stable element and its radioactive isotope behave similarly, or identically, in the body, but does not involve assumptions concerning the mathematical form of the retention function.

Tritiated water

Compartment (ship)

10.1088/0031-9155/13/4/305

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Citations (41)

Test of a micromegas detector with helium-based gas mixtures for active target time projection chambers utilizing radioactive isotope beams

Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment (2011)

D. Suzuki D. Bazin W. Mittig W. G. Lynch C. Hewko

MicroMegas detector

Time projection chamber

10.1016/j.nima.2011.09.026

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