Tan‐Lucien Mohammed

NYU Langone Health

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Nupur Verma

Baystate Medical Center

Bruno Hochhegger

University of Florida

Jacobo Kirsch

Cleveland Clinic Florida

Stephan Altmayer

Stanford Medicine

Hiren J. Mehta

University of Florida

Edson Marchiori

Universidade Federal do Rio de Janeiro

Jean Jeudy

University of Maryland, Baltimore

Michael A. Jantz

University of Florida

Matheus Zanon

Universidade Federal de Ciências da Saúde de Porto Alegre

Lamia Jamjoom

King Abdulaziz University

Cooperative Institutions

University of Florida

Florida College

University of Florida Health

Cleveland Clinic

University of Florida Health Science Center

University of Maryland, Baltimore

Universidade Federal de Ciências da Saúde de Porto Alegre

Irmandade da Santa Casa de Misericórdia de São Paulo

UF Health Shands Hospital

Oregon Health & Science University

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Low-dose Lung Cancer Screening at an Academic Medical Center

Academic Radiology (2018)

Altan Ahmed Nupur Verma Izabella Barreto Tan‐Lucien Mohammed

Center (category theory)

10.1016/j.acra.2017.12.023

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Citations (10)

Patient size matters: Effect of tube current modulation on size‐specific dose estimates (SSDE) and image quality in low‐dose lung cancer screening CT

Journal of Applied Clinical Medical Physics (2020)

Izabella Barreto Nupur Verma Nathan Quails Catherine Olguín Nathalie Correa

Abstract Purpose We compare the effect of tube current modulation (TCM) and fixed tube current (FTC) on size‐specific dose estimates (SSDE) and image quality in lung cancer screening with low‐dose CT (LDCT) for patients of all sizes. Methods Initially, 107 lung screening examinations were performed using FTC, which satisfied the Centers for Medicare & Medicaid Services' volumetric CT dose index (CTDI vol ) limit of 3.0 mGy for standard‐sized patients. Following protocol modification, 287 examinations were performed using TCM. Patient size and examination parameters were collected and water‐equivalent diameter ( D w ) and SSDE were determined for each patient. Regression models were used to correlate CTDI vol and SSDE with D w . Objective and subjective image quality were measured in 20 patients who had consecutive annual screenings with both FTC and TCM. Results CTDI vol was 2.3 mGy for all FTC scans and increased exponentially with D w (range = 0.96–4.50 mGy, R 2 = 0.73) for TCM scans. As patient D w increased, SSDE decreased for FTC examinations (R 2 = 1) and increased for TCM examinations (R 2 = 0.54). Image quality measurements were superior with FTC for smaller sized patients and with TCM for larger sized patients (R 2 > 0.5, P < 0.005). Radiologist graded all images acceptable for diagnostic evaluation of lung cancer screening. Conclusion Although FTC protocol offered a consistently low CTDI vol for all patients, it yielded unnecessarily high SSDE for small patients and increased image noise for large patients. Lung cancer screening with LDCT using TCM produces radiation doses that are appropriately reduced for small patients and increased for large patients with diagnostic image quality for all patients.

10.1002/acm2.12857

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Citations (14)

Pulmonary Lymphangitic Carcinomatosis From Renal Cell Carcinoma

Current Problems in Diagnostic Radiology (2018)

Leonard Riley Nupur Verma Tan‐Lucien Mohammed Ali Ataya

10.1067/j.cpradiol.2018.07.008

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Citations (2)

What's Next? – Career Conversations – Enlightening Decision Points for Every Career Stage

Academic Radiology (2022)

Tara Catanzano Nupur Verma David Sarkany Tan‐Lucien Mohammed Priscilla J. Slanetz

10.1016/j.acra.2022.09.007

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Triple‐phase abdominal computed tomography for detecting spontaneous portopulmonary shunts in cirrhotic patients

Journal of Gastroenterology and Hepatology (2012)

Germán González Lana M. Wilkinson Carolina Carcano Anand Kumar Tan‐Lucien Mohammed

Data on prevalence of portopulmonary shunts (PPS) are quite limited. Most studies have used cineportography or echocardiography for diagnosis. Only few recent case reports have reported the use of computed tomography (CT) for identification of PPS. This study tried to determine the prevalence of PPS in patients with cirrhosis using contrast-enhanced CT of the abdomen, and to determine their association with demographic and clinical characteristics.A total of 150 subjects with cirrhosis who had previously undergone triple-phase CT were analyzed. PPS was diagnosed when at least one esophageal varix met all of the following criteria: (i) it could be followed cephalad into the chest to the level of the inferior pulmonary vein or left atrium; (ii) it abutted the wall of either of these structures; (iii) it had luminal continuity with one of these structures; and (iv) it was no longer seen one slice above the level of contact.Of 150 subjects, 18 were excluded for incomplete data. The prevalence of PPS was found to be 26/132 (19.7%). Of these, 14 (53.8%) patients had PPS draining into the left atrium and 12 (46.2%) had those draining into one of the pulmonary veins. Presence of PPS was associated with the presence of varices at endoscopy, ascites, thrombocytopenia and splenomegaly.In our study, the largest study on PPS to date, the prevalence of PPS in cirrhotic patients using triple phase CT was found to be 19.7%. CT may be a useful technique to study PPS and their clinical implications.

Portopulmonary hypertension

Varix

10.1111/j.1440-1746.2012.07247.x

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From the Radiologic Pathology Archives: Cardiac Lymphoma: Radiologic-Pathologic Correlation

Radiographics (2012)

Jean Jeudy Jacobo Kirsch Fabio Tavora Allen Burke Teri J. Franks

Lymphoma of the heart and pericardium is usually present as one aspect of disseminated disease and rarely occurs as a primary malignancy. It accounts for 1.3% of primary cardiac tumors and 0.5% of extranodal lymphomas. Cardiac lymphomas are most commonly diffuse large cell lymphomas and frequently manifest as an ill-defined, infiltrative mass. Atrial location is typical; the right atrium is most often affected. Pericardial thickening or effusion is often a common early feature of disease. Infiltration of atrial or ventricular walls with extension along epicardial surfaces is also a notable feature. At computed tomography, the attenuation of cardiac lymphoma may be similar to or lower than that of normal myocardium. At magnetic resonance imaging, it has variable signal intensity and contrast enhancement. Clinical manifestations may include pericardial effusion, cardiac arrhythmias, and a variety of nonspecific electrocardiographic abnormalities, notably first- to third-degree atrioventricular block. Treatment most commonly includes anthracycline-based chemotherapy and anti-CD20 treatment. Chemotherapy has been used alone or combined with radiation therapy. Palliative surgery has been performed, mainly for tumor debulking. The prognosis for patients with either primary or secondary lymphomatous heart involvement is usually poor; late diagnosis is one of the major factors affecting outcome. © RSNA, 2012

10.1148/rg.325115126

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Citations (97)

A small pulmonary nodule, found incidentally.

Cleveland Clinic Journal of Medicine (2007)

Aqeel A. Chowdhry Peter J. Mazzone Tan‐Lucien Mohammed

Nodule (geology)

Solitary pulmonary nodule

10.3949/ccjm.74.7.531

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Citations (0)

Computed Tomography Correlation of Airway Disease With Bronchoscopy: Part I—Nonneoplastic Large Airway Diseases

Current Problems in Diagnostic Radiology (2014)

Emmanuel C. Obusez Lamia Jamjoom Jacobo Kirsch Thomas R. Gildea Tan‐Lucien Mohammed

10.1067/j.cpradiol.2014.05.002

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Citations (11)

SU-F-207-02: Use of Postmortem Subjects for Subjective Image Quality Assessment in Abdominal CT Protocols with Iterative Reconstruction

Medical Physics (2015)

Anna Mench I Lipnharski C Carranza L Sinclair R Lamoureux

Purpose: New radiation dose reduction technologies are emerging constantly in the medical imaging field. The latest of these technologies, iterative reconstruction (IR) in CT, presents the ability to reduce dose significantly and hence provides great opportunity for CT protocol optimization. However, without effective analysis of image quality, the reduction in radiation exposure becomes irrelevant. This work explores the use of postmortem subjects as an image quality assessment medium for protocol optimizations in abdominal CT. Methods: Three female postmortem subjects were scanned using the Abdomen-Pelvis (AP) protocol at reduced minimum tube current and target noise index (SD) settings of 12.5, 17.5, 20.0, and 25.0. Images were reconstructed using two strengths of iterative reconstruction. Radiologists and radiology residents from several subspecialties were asked to evaluate 8 AP image sets including the current facility default scan protocol and 7 scans with the parameters varied as listed above. Images were viewed in the soft tissue window and scored on a 3-point scale as acceptable, borderline acceptable, and unacceptable for diagnosis. The facility default AP scan was identified to the reviewer while the 7 remaining AP scans were randomized and de-identified of acquisition and reconstruction details. The observers were also asked to comment on the subjective image quality criteria they used for scoring images. This included visibility of specific anatomical structures and tissue textures. Results: Radiologists scored images as acceptable or borderline acceptable for target noise index settings of up to 20. Due to the postmortem subjects’ close representation of living human anatomy, readers were able to evaluate images as they would those of actual patients. Conclusion: Postmortem subjects have already been proven useful for direct CT organ dose measurements. This work illustrates the validity of their use for the crucial evaluation of image quality during CT protocol optimization, especially when investigating the effects of new technologies.

Image noise

10.1118/1.4925246

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Citations (0)

Appropriateness of Computed Tomography and Ultrasound for Abdominal Complaints in the Emergency Department

Current Problems in Diagnostic Radiology (2020)

Martina Zaguini Francisco Stephan Altmayer Nupur Verma Guilherme Watte Marina de Campos Brandao

10.1067/j.cpradiol.2020.11.004

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Citations (12)