Journal Article Acrosin activity in human spermatozoa in relation to semen quality and in-vitro fertilization Get access C.J. De Jonge, C.J. De Jonge 1 Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke's Medical CenterChicago, IL 60612-3864, USA 1To whom correspondence should be addressed at: Department of Obstetrics and Gynecology, University of Nebraska Medical Center, 600 South 42nd Street, Omaha, NE 68198-3255, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar S.M. Tarchala, S.M. Tarchala Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke's Medical CenterChicago, IL 60612-3864, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar R.G. Rawlins, R.G. Rawlins Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke's Medical CenterChicago, IL 60612-3864, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Z. Binor, Z. Binor Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke's Medical CenterChicago, IL 60612-3864, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar E. Radwanska E. Radwanska Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke's Medical CenterChicago, IL 60612-3864, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Reproduction, Volume 8, Issue 2, 1 February 1993, Pages 253–257, https://doi.org/10.1093/oxfordjournals.humrep.a138033 Published: 01 February 1993 Article history Received: 05 June 1992 Accepted: 09 October 1992 Published: 01 February 1993
Proximal, distal, and peritubal damage can be caused by a number of pathologic processes such as inflammation, endometriosis, and surgical trauma. The diagnosis of tubal occlusion relies primarily on hysterosalpingography, hysteroscopy, and laparoscopy. A number of innovative diagnostic procedures such as sonosalpingography, falloposcopy, and selective salpingography improved our ability to accurately diagnose tubal pathology. The long-standing surgical corrective approach to treat tubal occlusion has been replaced by noninvasive methods in selected patients with endoluminal damage. The development of noninvasive transcervical catheter methods to recanalize proximally obstructed fallopian tubes also allows access to the fallopian tubes for deposition of gametes and embryos and improves the diagnosis and treatment of tubal pregnancies. Transcervical tubal cannulation reduces the risks, costs, and morbidity of surgical procedures. The diverse applications of the transcervical tubal approach may also replace surgical invasive procedures in assisted reproductive procedures. Although radical changes have occurred in the treatment of proximal tubal occlusion, the repair of distal and peritubal damage frequently yields disappointing results, and will probably remain the challenge of the 1990s.
Seventeen women complaining of infertility (one with primary amenorrhoea, 14 with secondary amenorrhoea, and two with oligomenorrhoea) all had hyperprolactinaemia and were treated with clomiphene citrate and human chorionic gonadotrophin (HCG), and plasma oestradiol, FSH and LH levels were measured. Although adequate pre-ovulatory oestradiol levels were present, the surge of LH was absent until the injection of HCG after which all patients ovulated. There were 12 pregnancies in 9 patients resulting in 10 full-term livebirths, one premature livebirth and one continuing pregnancy. The relevance of these findings to the possible role of prolactin in amenorrhoea is discussed.
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