Mohamed A. Sayed

Cairo University

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Door-to-door survey of major neurological disorders (project) in Al Quseir City, Red Sea Governorate, Egypt

Neuropsychiatric Disease and Treatment (2013)

Wafa Farghaly Hamdy N. El-Tallawy Rageh Ghaydaa A. Shehata Reda Badry

Abstract: A door-to-door survey, including every household, was conducted for all inhabitants of Al Quseir City (33,283), Red Sea Governorate, Egypt by three specialists of neurology as well as nine senior staff members of neurology and 15 female social workers to assess the epidemiology of major neurological disorders. Over six phases, from July 1, 2009 to January 31, 2012, screening of all eligible people in the population was carried out, by which case ascertainment of all major neurological disorders included in the study was done according to the accepted definitions and diagnostic criteria of the World Health Organization. The order of frequency of prevalence of the studied neurological disorders was dementia (3.83% for those aged > 60 years), migraine (2.8% for those aged > 8 years), stroke (6.2/1000 for those aged > 20 years), epilepsy (5.5/1000), Parkinson's disease (452.1/100,000 for those aged > 40 years), cerebral palsy (3.6/1000 among children < 18 years), spinal cord disorders (63/100,000) dystonia (39.11/100,000), cerebellar ataxia (30.01/100,000), trigeminal neuralgia (28/100,000 for those aged > 37 years), chorea (21.03/100,000), athetosis (15/100,000), and multiple sclerosis (13.74/100,000). The incidence rates of stroke, epilepsy, and Bell's palsy were 181/100,000, 48/100,000, and 98.9/100,000 per year, respectively. Keywords: prevalence, incidence, neurological disorders

10.2147/ndt.s36956

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Citations (52)

Cross-cultural Study of the Personality Inventory for the DSM-5 (PID-5) across the Portuguese and the United Arab Emirates (UAE) Community and Clinical Populations

Clinical Practice and Epidemiology in Mental Health (2022)

Olga Coelho Rute Pires Ana Sousa Ferreira Bruno Gonçalves Samia A. Alkhoori

The present paper focused on compare the PID-5 mean score levels across two matched community and clinical samples of Portugal and the UAE.The generalizability and universality of the Alternative Model of Personality Disorders has been thoroughly studied through the Personality Inventory for DSM-5 (PID-5) across countries and languages. However, studies comparing Western and Middle Eastern countries are still limited, in particular those who assess the PID-5 measurement invariance.We examined measurement invariance of the PID-5 scales across matched Emirati and Portuguese clinical and nonclinical groups, as well as compare and contrast the PID-5 mean score levels across both countries and samples.The Arabic and the Portuguese versions of the PID-5 was administered to Emirati community participants (N = 300, 80% women and 20% men, Mage = 27.95) which were matched with Portuguese community participants (N = 300, 80.3% women and 19.7% men, Mage = 28.96), as well as clinical participants of the UAE (N = 150, 61.3% women and 38.7% men, Mage = 31.29) and Portugal (N = 150, 52% men and 48% women, Mage = 44.97). We examined measurement invariance through an unrestricted Factor Analysis based program, and mean scores levels were compared and analyzed.Our findings supported the PID-5 measurement invariance across the Emirati and Portuguese clinical samples pointing to the universality and generalizability of the Alternative Model of Personality Disorders. The Emirati psychiatric sample exhibited somehow higher results than the Portuguese psychiatric participants, albeit the small effect size for most of the PID-5 scales.Further research is needed to examine the applicability of the PID-5 across non-clinical representative samples of Portugal and the UAE, and other Middle Eastern countries.

10.2174/17450179-v18-e2207130

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Citations (2)

CONCEPTUALIZATION OF MENTAL ILLNESS WITHIN ARAB CULTURES: MEETING CHALLENGES IN CROSS-CULTURAL SETTINGS

Social Behavior and Personality An International Journal (2003)

Mohamed A. Sayed

This article reviews some of the cultural characteristics and conceptualizations that distinguish Arab patients. It is important to note that the terms Arab and Arabic do not necessarily indicate a monolithic approach. Conceptually, the term Arabic denotes a common language, geography, history and shared values and characteristics. There are vast differences within different Arab cultures which may converge and diverge to form what is sometimes “lumped together” as Arab culture. The paper also attempts to delineate some of the cultural barriers that may be significant in explaining a set of mechanisms that facilitate or hinder the seeking of psychological help by Arab patients within given psychotherapeutic relationships. Issues of cultural transference and counter transference are briefly discussed. Case studies are given to illustrate how to overcome such difficulties, especially when they pertain to therapeutic encounters between Arab patients and their Western therapists and the ensuing role expectations and role confusions.

10.2224/sbp.2003.31.4.333

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Citations (47)

Bacterial stroke-associated pneumonia: microbiological analysis and mortality outcome

BMC Neurology (2024)

Alshaimaa Mahmoud Aboulfotooh Heba Sherif Abdel Aziz Marwa M. Zein Mohamed A. Sayed Ahmed R. N. Ibrahim

Abstract Background Stroke-associated pneumonia (SAP) considerably burden healthcare systems. This study aimed to identify predictors of developing SAP in acute ischemic stroke patients admitted to the Stroke Unit at Manial Specialized Hospital factors with microbiological causality and impact on 30-day mortality. Methods This was a retrospective cohort study. All patients with acute ischemic stroke admitted to the Stroke Unit at Manial Specialized Hospital (from February 2021 to August 2023) were divided into the SAP and non-SAP groups. Detailed clinical characteristics and microbiological results were recorded. Results Five hundred twenty-two patients diagnosed with acute ischemic stroke (mean age of 55 ± 10) were included. One hundred sixty-nine (32.4%) of stroke patients developed SAP; Klebsiella pneumoniae was the most commonly detected pathogen (40.2%), followed by Pseudomonas aeruginosa (20.7%). Bacteremia was identified in nine cases (5.3%). The number of deaths was 11, all of whom were diagnosed with SAP, whereas none from the non-SAP group died ( P < 0.001). The binary logistic regression model identified three independent predictors of the occurrence of SAP: previous history of TIA/stroke (OR = 3.014, 95%CI = 1.281–7.092), mechanical ventilation (OR = 4.883, 95%CI = 1.544–15.436), and bulbar dysfunction (OR = 200.460, 95%CI = 80.831-497.143). Conclusions Stroke-associated pneumonia was reported in one-third of patients with acute ischemic stroke, adversely affecting mortality outcomes. Findings showed that the main predictors of SAP were bulbar dysfunction, the use of mechanical ventilation and previous history of TIA/stroke. More attention to these vulnerable patients is necessary to reduce mortality.

Stroke

Bacteremia

10.1186/s12883-024-03755-4

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Citations (1)

Validity of flexible bronchoscopy in the diagnosis of chronic cough in children attending Assiut university children hospital

Egyptian Journal of Chest Diseases and Tuberculosis (2021)

Yasser F. Abdel‐Raheem Moustafa M. El–Saied Mohamed A. Sayed Ali A. Hasan MostafaA Mohamed

Context Chronic cough in children is a major health problem with an increased prevalence from 8 to 20.78% between 1999 and 2016. Flexible bronchoscope has become one of the most valuable tools in the diagnostic workup of unexplained chronic cough in children. Aims To assess the children with chronic cough using flexible bronchoscopy in order to diagnose the underlying causes that remain otherwise unexplained by noninvasive diagnostic tests. Settings and design Observational cohort study. Patients and methods Children with unexplained chronic cough underwent flexible bronchoscopy during the period from October 2017 to December 2019. Bronchoalveolar lavage (BAL) was done for cytologic examination and microbiologic studies. Results This study involved 60 children, aged from 2 months to 14 years. Flexible bronchoscopy demonstrated positive findings in 65% of cases. The most common finding was congenital airway anomalies in 25% of cases. The second most common finding was visible bronchitis in 21.67% of cases. Other bronchoscopic findings included endobronchial mucous plug (5%), foreign body aspiration (6.67%), extrinsic compression on the airways (10%), and adenoid hypertrophy (1.66%). Cytologic examination of BAL fluid showed that neutrophilia was the most common finding. Haemophilus influenzae was the most common isolated organism in the BAL fluid samples. Conclusions Flexible bronchoscopy is a valuable safe tool in the diagnosis of chronic cough in children. BAL helped in the diagnosis of the underlying etiology by providing samples for cytologic and microbiologic studies.

Chronic Cough

Etiology

Neutrophilia

Chronic bronchitis

Flexible bronchoscopy

10.4103/ecdt.ecdt_4_20

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Citations (1)

Prevalence of Alzheimer dementia in Upper Egypt (desert areas)

The Egyptian Journal of Neurology Psychiatry and Neurosurgery (2019)

Hamdy N.A. El Tallawy Wafaa M.A. Farghaly Mohamed Abd El Hamed Reda Badry Usama Khaled

Alzheimer's disease (AD) is the commonest type of Dementia worldwide. It rapidly increases with aging especially over 70 years. The aims of this study are to determine the prevalence of AD in Egyptian desert areas and to identify the risk factors and presenting symptoms. This study was carried out on desert areas Al Kharga district and Al Quseir city. All population aged 50 years and more (12,508) were included through door to door survey by seven Neuropsychiatrists. They were screened by standardized questionnaire prepared specifically. Positive cases were invited to attend Assiut Univ. Hospital where clinical evaluation, according to DSM-IV R. and necessary psychometric tests were applied. One hundred twenty-six patients with AD were diagnosed out of 12,508 people aged 50 years; yielding a prevalence of 1%. Prevalence increases with age, from 0.34% for those aged 60 ≤ 70 years to 2.9% for subjects aged 70 ≤ 80 years, and 9.74% for those aged 80 years and more. AD is more common among females than males in all ages. Eighty-five percent of diagnosed patients are of mild and moderate degrees. Hypertension (14.3%), smoking (10.3%), diabetes (8.73%), prior epilepsy (5.6%), and family history of AD (3.5%) are common risk factors. Impaired self-care (88.1%), memory loss (84.1%), impaired social judgment (77%), agnosia (58.7%), and behavioral changes (48.4%) are the most frequently encountered symptoms of AD. Prevalence of AD was 1% for population aged 50 years and more, reaching 9.7 for patients aged > 80 years. Early onset AD (< 65 years) was recorded in 7.9%.

10.1186/s41983-019-0074-y

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Citations (12)

ARABIC PSYCHIATRY AND PSYCHOLOGY: THE PHYSICIAN WHO IS A PHILOSOPHER AND THE PHYSICIAN WHO IS NOT A PHILOSOPHER: SOME CULTURAL CONSIDERATIONS

Social Behavior and Personality An International Journal (2002)

Mohamed A. Sayed

The major focus of this article is to examine the current status of Arab psychiatry as practiced today and to provide some historical, theoretical, clinical, and research issues using cross-cultural comparisons as a backdrop to the argument. The paper deals primarily with issues pertinent to the current understanding of cross-cultural phenomena within Arabic societies. It discusses issues relevant to the practices and applications of traditional psychiatric methods and their coexistence with some practices that might appear contradictory to Western notions of psychiatric conceptualization of mental illness. It gives a brief synopsis of the interplay of the traditional healing methods in psychiatric practices as well as the contribution and acceptance of modern psychiatric methods and interventions. The changing demographic features of many Western nations and the resulting challenges faced by mental-health professionals working with diverse populations have only recently begun to bring these ideas to the fore.

Argument (complex analysis)

10.2224/sbp.2002.30.3.235

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Citations (23)

Clinical Characteristics of Headache in Egyptian Patients with Idiopathic Epilepsy

Journal of Behavioral and Brain Science (2019)

Mohamed A. Sayed Hazem Ibrahim Alaaeldin Sedky Bekhit Mohamed N. Thabit Mostafa Abdelmomen

Purpose: Headache and epilepsy are common neurological disorders and their relationship is still incompletely known. The purpose of our work was to estimate the most common types of primary headache syndromes and its relation to seizure timing in epileptic patients in Upper Egypt. Patients & Methods: In a cross-sectional study, we evaluated headaches in 100 consecutive patients with idiopathic epilepsy attending the neurology outpatient clinic and the epilepsy clinic at Sohag university hospital by complete medical history, physical and neurologic examination EEG and CT brain. Results: Of our study population, 78% of patients with epilepsy reported headaches. Migraine occurred in 70.6% of patients with headache followed by tension-type headache in 25.58% of patients and other types of headaches occurred in 2.56% of patients. There were 8 patients (10.1%) had a pre-ictal headache, 52 patients (66.5%) had a postictal headache and 39 patients (50%) had an interictal headache. In our study, we found that the occurrence of headache being linked to the female sex, lower mean age, lower mean age at the onset of epilepsy, focal epilepsy, longer duration of epilepsy, high frequency of seizures and the use of polytherapy of antiepileptics. Conclusion: Headache especially migraine is an important comorbidity of epilepsy and should receive more attention especially in female patients, patients with younger age, lower mean age at epilepsy onset, longer duration of the disease, patients on polytherapy, patients with higher frequency of seizures and patients with focal epilepsy.

Outpatient clinic

10.4236/jbbs.2019.93012

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Citations (4)

The Arabic Version of the Personality Inventory for the DSM-5 (PID-5) in a Clinical Sample of United Arab Emirates (UAE) Nationals

American Journal of Health Behavior (2020)

Olga Coelho Rute Pires Ana Sousa Ferreira Bruno Gonçalves Samia A. Alkhoori

Objectives: We aimed to test the potential of the Arabic version of the PID-5 to distinguish between clinical and non-clinical participants, as well as to examine its convergent validity and factor structure in an Emirati clinical sample. Methods: The Arabic version of the PID-5 was administered to a clinical sample comprised of 156 participants (Mage = 31.38, SD = 8.99, 37.8% male, 62.2% female) and a community sample also comprised of 156 participants (Mage = 31.43, SD = 9.52, 37.2% male, 62.8% female). We addressed the descriptive measures, internal consistency, mean rank scores differences, convergent validity with SCL-90-R, and PID-5's factor structure. Results: As expected, the clinical sample presented statistically significantly higher scores than the non-clinical sample, with medium to high effect sizes. In addition, all the PID-5 domains showed positive correlations with most of the symptomatic constellations of the SCL-90-R as well as the PID-5 facets with all their SCL-90-R counterparts. However, our findings did not entirely replicate the PID-5 original 5-factor structure, as only a 4-factor solution was retained. Conclusions: Future studies with the Arabic PID-5 in clinical samples are needed to understand its relevance and clinical utility in Arabic countries.

Sample (material)

DSM-5

10.5993/ajhb.44.6.5

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Citations (7)

Epidemiology of dystonia, chorea, and athetosis in Al Quseir City (Red Sea Governorate), Egypt

The Egyptian Journal of Neurology Psychiatry and Neurosurgery (2019)

Reda Badry Mohamed A. Abdelhamed Mohamed A. Sayed Abeer Abd ElHady Mohamed Mostafa

Movement disorders are common neurological problems, but epidemiological studies are lacking in our locality. Type of movement disorder depends on the site of the lesion and the type of pathologic changes. To estimate the prevalence rate of dystonia, chorea, and athetosis, in Al Quseir City (Red Sea Governorate), Egypt. This study is a part of a door to door survey of major neurological disorders that was conducted in Al Quseir City, Red Sea Governorate, Egypt, on a sample size of 33,285 subjects. They were screened through 3 neurologists and 15 social workers. Then, each of the three staff members of neurology subjected positive cases to meticulous clinical evaluation separately. Thirteen cases with dystonia, 7 cases with chorea and 5 cases with athetosis were found with prevalence rates of 39/100,000, 21/100,000, and 15/100,000 respectively. Prevalence rates of dystonia, chorea, and athetosis in Al Quseir City are higher than those of the worldwide. This may be attributed to some specific environmental factors of this locality.

Athetosis

Movement Disorders

10.1186/s41983-019-0109-4

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Citations (5)