Simin Torabinejad

Shiraz University of Medical Sciences

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Perikala V. Kumar

Shiraz University of Medical Sciences

Zohreh Mostafavi‐Pour

Shiraz University of Medical Sciences

ΜM

Μohammad Mohammadianpanah

Shiraz University of Medical Sciences

Sedigheh Kianpour

Shiraz University of Medical Sciences

Shapour Omidvari

Shiraz University of Medical Sciences

Bita Geramizadeh

Shiraz University of Medical Sciences

Ahmad Mosalaei

Shiraz University of Medical Sciences

Negar Azarpira

Shiraz University of Medical Sciences

Mohammad Hadi Bagheri

Kermanshah University of Medical Sciences

Ahmad Monabati

Shiraz University of Medical Sciences

Cooperative Institutions

Shiraz University of Medical Sciences

Shiraz University

Namazi Hospital

Universitat Autònoma de Barcelona

Massachusetts General Hospital

Oita University

University Hospital of Geneva

Stem Cell Technology Research Center

Faghihi Hospital

Harvard University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Primary epidural malignant hemangiopericytoma of thoracic spinal column causing cord compression: case report

Sao Paulo Medical Journal (2004)

Μohammad Mohammadianpanah Simin Torabinejad Mohammad Hadi Bagheri Shapour Omidvari Ahmad Mosalaei

Hemangiopericytoma is an uncommon mesenchymal neoplasm that rarely affects the spinal canal. Primary malignant hemangiopericytoma of the spinal column is extremely rare.

Hemangiopericytoma

Vertebral column

Spinal cord compression

Spinal column

Thoracic vertebrae

10.1590/s1516-31802004000500009

Cite

Citations (20)

Primary chondrosarcoma of phalanx

The Foot (2004)

Μohammad Mohammadianpanah Simin Torabinejad Mohammad Hadi Bagheri Shapour Omidvari Ahmad Mosalaei

Phalanx

Primary bone

10.1016/j.foot.2004.01.001

Cite

Citations (1)

Nephritic-nephrotic syndrome as a presentation of BK virus infection.

DOAJ (DOAJ: Directory of Open Access Journals) (2011)

Nima Derakhshan Dorna Derakhshan Simin Torabinejad Ali Derakhshan

BK virus (BKV) is increasingly found as an important cause of allograft nephropathy. Nephrotic syndrome is not a usual manifestation of BKV nephropathy. Here, we report a 12-year-old boy, a case of end-stage renal disease due to nephronophthisis, who got the kidney transplanted from a 16-year-old cadaver, and after 18 months of uneventful transplantation on triple immunosuppressive therapy (mycophenolate mofetil (MMF), cyclosporin and prednisolone), presented with nephrotic feature (edema, heavy proteinuria, hypoalbuminemia and hyperlipidemia). Kidney biopsy was in favor of BKV infection and eventually ended in graft failure.

Hypoalbuminemia

Prednisolone

Nephritic syndrome

Membranous Nephropathy

Source

Cite

Citations (2)

The Healing Effect of Adipose-Derived Mesenchymal Stem Cells in Full-thickness Femoral Articular Cartilage Defects of Rabbit.

PubMed (2015)

Davood Mehrabani M Babazadeh Nader Tanideh S Zare S Hoseinzadeh

Articular cartilage defect can lead to degradation of subchondral bone and osteoarthritis (OA).To determine the healing effect of transplantation of adipose-derived mesenchymal stem cells (Ad-MSCs) in full-thickness femoral articular cartilage defects in rabbit.12 rabbits were equally divided into cell-treated and control groups. In cell-treated group, 2×10(6) cells of third passage suspended in 1 mL of DMEM was injected into articular defect. The control group just received 1 mL of DMEM. Dulbecco's modified Eagles medium (DMEM) supplemented with 10% fetal bovine serum (FBS), 1% penicillin and streptomycin and 2 mM L-glutamine were used for cell culture. To induce cartilage defect, 4 mm articular cartilage full-thickness defect was created in the knee. For histological evaluation in each group (H&E, safranin-O and toluidine blue), 3 rabbits were sacrificed 4 weeks and 3 animals, 8 weeks after cell transplantation.In cell therapy group post-transplantation, no abnormal gross findings were noticed. Neo-formed tissues in cell-treated groups were translucent with a smooth and intact surface and less irregularity. In cell-treated group after 8 weeks post-transplantation, the overall healing score of experimental knees were superior when compared to other groups.We showed that Ad-MSCs, as an available and non-invasive produced source of cells, could be safely administered in knee osteochondral defects.

Cell therapy

Source

Cite

Citations (23)

Protective Effects of Vitamin E and/or Quercetin Co-Supplementation on the Morphology of Kidney in Cyclosporine A-Treated Rats

Iranian journal of medical sciences (2009)

Zohreh Mostafavi‐Pour Mahmood Vessal Fatemeh Zal Zahra Khoshdel Simin Torabinejad

Background: Cyclosporine A (CsA) is a nephrotoxic immunosuppressive drug. Antioxidants might attenuate its toxicity. In the present study, the effects of vitamin E and quercetin on the morphology of kidney in CsA-treated rats were investigated. Methods: Six groups of rats were used in this gavage feeding study either for 4 or 8 weeks. Groups 1 and 2 received either olive oil or 25% ethanol in olive oil per day. Group 3 received CsA (25 mg/kg/day) in olive oil. All other groups received CsA plus the following: group 4, vitamin E (100 mg/kg/day) in olive oil; group 5, quercetin (15 mg/kg/day) in 25% ethanol in olive oil; and group 6, vitamin E plus quercetin. In the final day of the study, the animals were sacrificed and kidney sections were prepared for morphologic studies using light microscopy. Results: Acute morphologic alterations induced by CsA in the kidney tubules included isometric vacuolization, brush border loss, microcalcification, and presence of inclusion bodies. Smooth muscle degeneration and necrosis were developed in arterioles. Treatment with vitamin E plus quercetin prevented severe, moderate, and mild abnormalities of the tubules. However fibrosis was the only microscopic change of the interstitium that was not present in animals treated with vitamin E plus quercetin after both periods. Some mild morphological changes of the blood vessels such as arteriolar medial smooth muscle degeneration and necrosis, arteriolar myocyte dropout and arteriolar wall hyalinization caused by CsA disappeared with administration of vitamin E, quercetin or vitamin E plus quercetin in both periods.

Nephrotoxicity

Vacuolization

Hyaline

Source

Cite

Citations (6)

Accuracy of intra-operative frozen section consultation in south of Iran during four years

Indian Journal of Pathology and Microbiology (2010)

Bita Geramizadeh TaghiRezai Larijani Seyed Mohammad Owji SeyedYahya Attaran Simin Torabinejad

Background: Accuracy of intraoperative frozen section diagnosis is an important part of quality control in surgical pathology. In this study we try to evaluate the frozen section diagnosis in our center, a referral center in southern Iran. Materials and Methods: During the four-year-period of study, all the frozen sections in the affiliated hospitals of Shiraz University of Medical Sciences were evaluated. Discrepant cases were studied to find out reasons for their inaccuracies. Results: In the four years, 759 frozen sections have been done, 25 of which showed discordant results. The most common site of frozen section and discrepancy was in central nervous system tumors. The reason for inaccuracy in frozen section diagnosis in 52% of cases was proved to be interpretative, 44% sampling error and the remainder due to lack of clinical information of the pathologist. Conclusion: Accuracy of our intraoperative consultation is comparable with other centers in Western countries. Most of the discrepancies can be prevented by providing more clinical information for the pathologist and more accurate sampling.

Section (typography)

Surgical pathology

10.4103/0377-4929.68250

Cite

Citations (13)

Combining effects of trichstatin A and 5-Aza-2-deoxycytidine on integrin α4 expression in human prostate cancer cell lines

Clinical Biochemistry (2011)

Sedigheh Kianpour Mokaram Pooneh Mehdi Dehghani Simin Torabinejad Sarva Keihani

Cancer cell lines

10.1016/j.clinbiochem.2011.08.470

Cite

Citations (0)

Osteoclastomalike Anaplastic Carcinoma of the Thyroid Gland Diagnosed by Fine Needle Aspiration Cytology

Acta Cytologica (1997)

Perikala V. Kumar Simin Torabinejad Gholam Hussein Omrani

Thyroid diseases are common among the female population in Iran; the main one is endemic colloid goiter. Thyromegaly can be due to neoplastic and nonneoplastic disorders. The clinical distinction between benign and malignant tumors of the thyroid gland is sometimes difficult. Fine needle aspiration (FNA) study can be used as a preliminary step for identifying such lesions.Two female patients aged 54 and 62 years were admitted to Nemazi Hospital, Shiraz, Iran, with the chief complaint of weight loss, rapid enlargement of the thyroid gland for the last few months and pressure symptoms in the neck. Clinically these cases were diagnosed as malignant thyroid lesions. However, for further diagnosis the tumors were aspirated. The smears revealed numerous osteoclastlike giant cells with intranuclear inclusions and numerous, isolated oval to spindle-shaped malignant cells. The smears were diagnosed as osteoclastlike anaplastic carcinoma of the thyroid.FNA is useful in the diagnosis of osteoclastomalike anaplastic carcinoma of the thyroid.

Anaplastic carcinoma

Cytopathology

Thyroid Nodules

10.1159/000333534

Cite

Citations (15)

Methylation of Integrin α4 and E-Cadherin Genes in Human Prostate Cancer

Pathology & Oncology Research (2015)

Zohreh Mostafavi‐Pour Sedigheh Kianpour Mehdi Dehghani Pooneh Mokarram Simin Torabinejad

DU145

Trichostatin A

Bisulfite sequencing

10.1007/s12253-015-9917-8

Cite

Citations (16)

Effect of Sodium Fluoride on Fracture Healing in Experimental Rabbits

Journal of Applied Animal Research (2008)

Mohammad Reza Azarpira Mohammad Jafar Emami Simin Torabinejad F. Abdinejad Negar Azarpira

Abstract Azarpira, M.R., Emami, M.J., Torabinejad, S., Abdinejad, F., Azarpira, N. and Mehrabani, D. 2008. Effect of sodium fluoride on fracture healing in experimental rabbits. J. Appl. Anim. Res., 34: 173–177. To determine the healing effect of sodium fluoride on experimentally induced transverse midshaft radial fracture, 60 (3 mo) healthy, white rabbits (Oryctolagus cuniculus) were divided into 6 groups including four-case groups (A, B, C and D) and two-controls (E and F). Sodium fluoride (5 mg/kg/d for groups A and C and 10 mg/kg/d for groups B and D) was administered to the case groups from the first day post-operation. Groups A, B and E were euthanized at the end of the second week and groups C, D and F at the end of the sixth week. There was a significant difference in cortical bone regeneration thickness between B, E and C, F groups. In groups A, B and E there was a significant difference in the thickness of regenerated trabecular bone. The radiological scores showed gradual movement toward union. So, sodium fluoride can stimulate osteogenesis in periosteal and central osteoblasts in fractures.

Sodium fluoride

10.1080/09712119.2008.9706965

Cite

Citations (0)