The indiscriminate application of diverse broad-spectrum antimicrobials has escalated nosocomial infections into a critical global public health quandary. Currently, traditional antibiotics' efficacy against these infections becomes limited, necessitating a concerted pursuit of more efficacious antimicrobial agents. It is noteworthy that taurine (tau) and cepharanthine (cep) are both biologically active compounds, with taurine constituting a vital nutrient to human health and cepharanthine exhibiting certain antibacterial attributes. However, while cepharanthine displays intrinsic antibacterial attributes, its monomeric utility is constrained. This study thus investigated the formulation process of merging taurine with cepharanthine, and rigorously assessed the antimicrobial potential of the taurine-cepharanthine complex (denoted as [cep][tau]). The outcomes indicated that this complex, [cep][tau], exhibited antibacterial activity against Staphylococcus aureus and Klebsiella pneumoniae that was on par with the efficacy of cepharanthine on its own. This observation implies that taurine did not antagonize the antibacterial potency of cepharanthine, offering novel avenues for the development of innovative pharmaceuticals targeting hospital-acquired infections.
Increasing environmental problems intensify the demand for high-performance environmental purification materials. MXene is a typical transition-metal carbide/nitride material with a two-dimensional geometric feature and a good deal of functional groups, and it is considered as an efficient adsorbent for removing pollutants from wastewater. However, the easy oxidation and relatively low adsorption capacity greatly restrict its application. In this study, the MXene/polydopamine (PDA) composite particles were fabricated through the biomimetic modification method of inducing the self-polymerization of dopamine in an MXene aqueous solution. Microstructure characterizations demonstrate that PDA facilitates the exfoliation of MXene. Adsorption measurements show that MXene and PDA exhibit an apparent synergistic effect in removing chromium hexavalent Cr(VI) from aqueous solution, and more PDA content leads to a larger synergistic effect. Consequently, the composite particles exhibit an ultrahigh adsorption capacity (862.3 mg/g). Specifically, even if the composite particles were stored in aqueous solution for 2 months, they still exhibit high adsorption ability with only a 3.3% loss in adsorption capacity, indirectly confirming the enhanced stability of MXene induced by PDA. Furthermore, the composite particles also show reduction ability to Cr(VI) and about 54.3% Cr(VI) can be reduced to harmless chromium trivalent Cr(III). This study provides a new method for the preparation of MXene-based adsorbents with excellent adsorption capacity and high stability, which has broad application prospects in the field of wastewater treatment.
Objective To observe the clinical effects of Jiaweibushenguchong antai soup treating habitual abortion.Method Twenty-five patients of habitual abortion,TCM jiaweibushenghong antai soup Fangji I was taken before pregnancy and Fangji II was taken after pregnancy,four times every week,and eight times as one therapeutic course.Results After one therapeutic course,18 cases were healed,4 cases displayed effects,3 cases had no effects.After the second therapeutic course,3 cases were healed,2 displayed effects,2 cases had no effects. The total effective ratio was 92%.Conclusion The effects of Jiaweibushenguchong antai soup treating habitual abortion is good.
The indiscriminate application of diverse broad-spectrum antimicrobials has escalated nosocomial infections into a critical global public health quandary. Currently, traditional antibiotics' efficacy against these infections becomes limited, necessitating a concerted pursuit of more efficacious antimicrobial agents. It is noteworthy that taurine (tau) and cepharanthine (cep) are both biologically active compounds, with taurine constituting a vital nutrient to human health and cepharanthine exhibiting certain antibacterial attributes. However, while cepharanthine displays intrinsic antibacterial features, its monomeric utility is constrained. This study thus investigated the formulation process of merging taurine with cepharanthine, and rigorously assessed the antimicrobial potential of the taurine-cepharanthine complex (denoted as [cep][tau]). The outcomes indicated that this complex, [cep][tau], exhibited antibacterial activity against Staphylococcus aureus and Klebsiella pneumoniae, which was on par with the efficacy of cepharanthine on its own. This observation implies that taurine did not antagonize the antibacterial potency of cepharanthine, offering novel avenues for the development of innovative pharmaceuticals targeting hospital-acquired infections.
Due to the incorporation of modern science and technology in the competitive sports,dash skills has been greatly improved.The appearance of all－weather runways,together with the application of compnter simulators,has significantly forwarded the scientific training.Dash skills have been developing since 1950's,when attention was paid to“backward stepping”,during the period in 1970's when people were concerned with“stepping－swaying”,and up to now when emphasis are placed on“gluteus－extensors and speedy－ground－touching”.The significance and function of speedy gluleus extensors as well as the development of them have fully been embodied in perfecting the dash skill training. [
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