Backbround: The risk of atrial fibrillation associated with left atrial (LA) remodeling is increasing in elderly hypertension (HTN) and LA volume and function have a prognostic importance. However, optimal target blood pressure (BP) for LA in elderly remains unclear. We assessed the hypothesis that intensive BP lowering therapy has a beneficial effect on LA structure and function in elderly HTN. Methods: We studied 265 subjects with age≥65 yrs, who were divided into 4 groups by mean office BP for 2 years; normal subjects (n=73, 75±5 yrs, 37 men), intensive controlled HTN (BP Results: There was no difference in LV ejection fraction among 4 groups. LA volume, LAEF, LA strain and SR in intensive controlled HTN were more preserved than good or poor controlled HTN and were comparable to normal including diastolic function. Comparisons are shown in the table. Conclusions: LA structure and LA function such as relaxation, conduit function and contraction were preserved in intensive controlled HTN associated with preserved diastolic function. Intensive BP lowering therapy (systolic BP
Background: Left ventricular (LV) longitudinal strain is reported to be reduced in heart failure with preserved ejection fraction (HFpEF). However, the role and mechanism of LV deformational parame...
