The element $|V_{cb}|$ of the Cabibbo-Kobayashi-Maskawa matrix is measured using semileptonic $B_s^0$ decays produced in proton-proton collision data collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3 fb$^{-1}$. Rates of $B_s^0 \to D_s^{-} \mu^+ \nu_{\mu}$ and $B_s^0 \to D_s^{*-} \mu^+ \nu_{\mu}$ decays are analyzed using hadronic form-factor parametrizations derived either by Caprini, Lellouch and Neubert (CLN) or by Boyd, Grinstein and Lebed (BGL). The measured values of $|V_{cb}|$ are ${(41.4 \pm 0.6 \pm 0.9 \pm 1.2)\times 10^{-3}}$ and ${(42.3 \pm 0.8 \pm 0.9 \pm 1.2)\times 10^{-3}}$ in the CLN and BGL parametrization, respectively. The first uncertainty is statistical, the second systematic, and the third is due to the external inputs used in the measurement. These results are in agreement with those obtained from decays of $B^+$ and $B^0$ mesons. They are the first determinations of $|V_{cb}|$ at a hadron-collider experiment and the first using $B_s^0$ meson decays.

CP violation

10.1103/physrevd.101.072004

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FOXM1 transcriptional regulation

Biology of the Cell (2024)

Mengxi Li Xuzheng Gao Yanting Su Shigang Shan Wenbin Qian

Abstract FOXM1 is a key transcriptional regulator involved in various biological processes in mammals, including carbohydrate and lipid metabolism, aging, immune regulation, development, and disease. Early studies have shown that FOXM1 acts as an oncogene by regulating cell proliferation, cell cycle, migration, metastasis, and apoptosis, as well as genes related to diagnosis, treatment, chemotherapy resistance, and prognosis. Researchers are increasingly focusing on FOXM1 functions in tumor microenvironment, epigenetics, and immune infiltration. However, researchers have not comprehensively described FOXM1's involvement in tumor microenvironment shaping, epigenetics, and immune cell infiltration. Here we review the role of FOXM1 in the formation and development of malignant tumors, and we will provide a comprehensive summary of the role of FOXM1 in transcriptional regulation, interacting proteins, tumor microenvironment, epigenetics, and immune infiltration, and suggest areas for further research.

FOXM1

Infiltration (HVAC)

10.1111/boc.202400012

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Test of lepton flavour universality using $B^0 \to D^{*-}\tau^+\nu_{\tau}$ decays with hadronic $\tau$ channels

HAL (Le Centre pour la Communication Scientifique Directe) (2023)

R. Aaij A. S. W. Abdelmotteleb Carlos Abellán Beteta F. Abudinén T. Ackernley

The branching fraction $\mathcal{B}(B^0 \to D^{*-}\tau^+\nu_{\tau})$ is measured relative to that of the normalisation mode $B^0 \to D^{*-}\pi^+\pi^-\pi^+$ using hadronic $\tau^+ \to \pi^+\pi^-\pi^+(\pi^0)\bar{\nu}_{\tau}$ decays in proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the LHCb experiment, corresponding to an integrated luminosity of 2 fb$^{-1}$. The measured ratio is $\mathcal{B}(B^0 \to D^{*-}\tau^+\nu_{\tau})/\mathcal{B}(B^0 \to D^{*-}\pi^+\pi^-\pi^+)= 1.70 \pm 0.10^{+0.11}_{-0.10}$, where the first uncertainty is statistical and the second is related to systematic effects. Using established branching fractions for the $B^0 \to D^{*-}\pi^+\pi^-\pi^+$ and $B^0 \to D^{*-} \mu^+\nu_\mu$ modes, the lepton universality test, $\mathcal{R}(D^{*-}) \equiv \mathcal{B}(B^0 \to D^{*-}\tau^+\nu_{\tau})/\mathcal{B}(B^0 \to D^{*-} \mu^+\nu_\mu)$ is calculated, $$ \mathcal{R}(D^{*-}) = 0.247 \pm 0.015 \pm 0.015 \pm 0.012\, , $$ where the third uncertainty is due to the uncertainties on the external branching fractions. This result is consistent with the Standard Model prediction and with previous measurements.

Flavour

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Observation of the $B^+ \to D^{*-}K^+\pi^+$ decay : arXiv

R. Aaij Gregory Ciezarek Paula Collins S. Roiser Wenbin Qian

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Measurement of the CKM angle $γ$ using the $B^{\pm}\rightarrow D^{*} h^{\pm}$ channels

arXiv (Cornell University) (2023)

R. Aaij A. S. W. Abdelmotteleb Carlos Abellán Beteta F. Abudinén T. Ackernley

A measurement of the $CP$-violating observables from $B^{\pm}\rightarrow D^* K^{\pm}$ and $B^{\pm}\rightarrow D^* \pi^{\pm}$ decays is presented, where $D^* (D) $ is an admixture of $D^{*0}$ and $\bar{D}^{*0}$ ($D^0$ and $\bar{D}^0$) states and is reconstructed through the decay chains $ D^* \rightarrow D\pi^0/\gamma$ and $D \to K_S^0 \pi^+\pi^-/K_S^0 K^+K^-$. The measurement is performed by analysing the signal yield variation across the $D$ decay phase space and is independent of any amplitude model. The data sample used was collected by the LHCb experiment in proton-proton collisions and corresponds to a total integrated luminosity of 9 fb$^{-1}$ at centre-of-mass energies of 7, 8 and 13 TeV. The CKM angle $\gamma$ is determined to be $(69^{+13}_{-14})^{\circ}$ using the measured $CP$-violating observables. The hadronic parameters $r^{D^* K^{\pm}}_B, r^{D^* \pi^{\pm}}_B, \delta^{D^* K^{\pm}}_B, \delta^{D^* \pi^{\pm}}_B$, which are the ratios and strong phase differences between favoured and suppressed $B^{\pm}$ decays, are also reported.

CP violation

Bar (unit)

10.48550/arxiv.2310.04277

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Measurement of the $CP$ asymmetry in $B^0_s -\overline B {^0 _s}$ mixing

Physical Review Letters (2016)

R. Aaij Gregory Ciezarek Paula Collins G. Collazuol S. Roiser

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