Abstract The present work demonstrates a method by which natural, non-UV absorbing penicillins can be derivatized to form phenacyl esters. The reaction is rapid and essentially completed in twenty minutes. A straight line correlation was found between the peak height of a phenacyl ester derivative and the amount of the penicillin, a fact which attests to the applicability of the method for quantisation. The phenacyl esters of the penicillins studied here were separated on a reversed phase column.
Abstract Trazodone, an anti‐depressant medication, is found in serum in the 500–1000 ng/mL range in patients taking therapeutic doses. Because of this relatively high concentration, it has been possible to devise an HPLC assay system using the rapid, convenient microscale procedure described previously by Lam et al. (Clin. Chem. 26, 963 1980) to prepare the sample for chromatography. To 0.1 mL serum were added 0.1 mL acetonitrile and 10 μL of 10% zinc sulfate in water. The mixture was centrifuged and 50 μL of the clear supernatant was injected into a reversed‐phase column which was eluted with 65% 0.05 M potassium phosphate−35% acetonitrile, with detection by ultraviolet absorbance at 210 nm. The trazodone elutes in 6 min, clearly resolved from endogenous interferences. The recovery of trazodone added to serum was better than 90%. Peak height was proportional to concentrations in the serum sample from 125 ng/mL to 3000 ng/mL.
Our work has broadly explored the applications of quantum mechanisms to robotics, consolidating the previously fragmented discussions across disciplines, each of which contributes a piece to the emerging field of quantum robotics. While much of our exploration of possibilities has been theoretical (as implementations of relevant quantum engineering are still far from practical), we have suggested some of the key ways that developments in quantum science and engineering will impact the world of robotics, much as they have already begun impacting other fields.
A robot is a physical hardware embodied agent, situated and operating in an uncertain and dynamic real-world environment [Matarić, 2007]. Typical robots have sensors by which they can perceive their environment's state (as well as their own), manipulators for acting in and affecting their environment, electronic hardware capable of real-time computation and control, and sophisticated software algorithms.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorescence labeling of dicarboxylic acids for high performance liquid chromatographic separationEli. Grushka, Stanley. Lam, and John. ChassinCite this: Anal. Chem. 1978, 50, 9, 1398–1399Publication Date (Print):August 1, 1978Publication History Published online1 May 2002Published inissue 1 August 1978https://pubs.acs.org/doi/10.1021/ac50031a053https://doi.org/10.1021/ac50031a053research-articleACS PublicationsRequest reuse permissionsArticle Views208Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
