A method that simply improves the quality (Q) factors of two-dimensional photonic crystal nanocavities using a three-dimensional finite-difference time domain calculation is described. The leaky area for a high-Q nanocavity mode is visualized in a real cavity structure by extracting the leaky components within a light cone in momentum space and by transferring them back into real space using an inverse Fourier transformation. The Q factor is remarkably improved by appropriately shifting the positions of air holes at the leaky area. We design three-missing-air-hole and zero-cell-defect nanocavities with Q factors of 5,000,000 and 1,700,000, respectively, for demonstration.

Leaky mode

Q factor

10.1364/oe.24.009541

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Citations (49)

All-1

Elsevier eBooks (2002)

Tatsuya Nakamura Carlo M. Croce Eli Canaani

10.1016/b0-12-227555-1/00002-2

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Citations (0)

Data from Wwox Suppresses Prostate Cancer Cell Growth through Modulation of ErbB2-Mediated Androgen Receptor Signaling

Haiyan Qin Dimitrios Iliopoulos Tatsuya Nakamura Stefan Costinean Stefano Volinia

<div>AbstractThe expression of the WWOX tumor suppressor gene is lost or reduced in a large fraction of various cancers, including prostate cancer. We previously reported that Wwox overexpression induced apoptosis and suppressed prostate cancer growth in vitro and in vivo. In this study, pathways through which Wwox contributes to control of prostate cancer cell growth have been investigated. We found that Wwox interacts with Ap2γ and prevents it from entering the nucleus to bind the ERBB2 promoter region to activate transcription of ERBB2, a mediator of androgen receptor activity and prostate cancer cell growth at limiting androgen concentration. Ectopic expression of Wwox reduced ErbB2 protein expression in vitro and expression of Wwox protein inversely correlated with expression of ErbB2 protein in prostate cancer tissues. Furthermore, Wwox suppressed Ap2γ/ErbB2–induced prostate cancer cell growth and suppressed prostate-specific antigen secretion through interaction with Ap2γ and down-modulation of ErbB2, an effect that required functional androgen receptor. (Mol Cancer Res 2007;5(9):957–65)</div>

WWOX

Ectopic expression

10.1158/1541-7786.c.6542880.v1

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Long Haul transmission of four-dimensional 64SP-12QAM signal based on 16QAM constellation for longer distance at same spectral efficiency as PM-8QAM

Tatsuya Nakamura Emmanuel Le Taillandier de Gabory Hidemi Noguchi Wakako Maeda Jun-ichi Abe

We propose a new 4D coded modulation format, 64SP-12QAM, with same SE as PM-8QAM and straightforwardly-switchable with PM-16QAM. We experimentally demonstrated over 0.2 dB better sensitivity for 64SP-12QAM compared to PM-8QAM, enabling a transmission reach extension to 6,000 km at 6b/s/Hz.

Modulation (music)

SIGNAL (programming language)

Spectral Efficiency

10.1109/ecoc.2015.7341874

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Citations (19)

Spatial response analysis on superconducting X-ray detectors by Low Temperature Scanning Synchrotron Microscopy

低温工学・超電導学会講演概要集 = Meetings of Cryogenics and Superconductivity (2001)

Harald Preßler Masahiro Ukibe M. Ohkubo Daiji Fukuda Hiroyuki Takahashi

X-ray detector

Source

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Optimization of a micro-strip gas chamber as a two-dimensional neutron detector using gadolinium converter

Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment (2003)

Sei Masaoka Tatsuya Nakamura H. Yamagishi Kazuhiko Soyama

Neutron Detection

Neutron Imaging

Position (finance)

10.1016/s0168-9002(03)02077-1

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Citations (13)

A study on the current and radiation noise from 30M to 3G Hz generated by slowly breaking silver compound contacts

Tatsuya Nakamura Kazuaki Miyanaga Yoshiki Kayano Hiroshi Inoue

Source

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Time-resolved catch and release of an optical pulse from a dynamic photonic crystal nanocavity

Optics Express (2011)

Jeremy Upham Yoshinori Tanaka Yousuke Kawamoto Yoshiya Sato Tatsuya Nakamura

We perform time-domain measurements of the interaction between light and silicon photonic crystal nanocavities under dynamic Q factor control. Time-resolved evidence of optical pulse capture and release on demand is demonstrated and compared for samples with dynamic Q ranges from ~3,000 to 26,000 and from 18,500 to 48,000. Observing the energy behaviour in response to dynamic control provides insight not available with time-integrated measurements into factors influencing device performance such as carrier absorption and pulse capture efficiency.

10.1364/oe.19.023377

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Citations (16)

Experimental Demonstration of the Improvement of System Sensitivity Using Multiple State Trellis Coded Optical Modulation with QPSK and 16QAM Constellations

Optical Fiber Communication Conference (2015)

Emmanuel Le Taillandier de Gabory Tatsuya Nakamura Hidemi Noguchi Wakako Maeda Sadao Fujita

We evaluated experimentally 2, 8, 32 state 32Gbaud TCM-QPSK and TCM-16QAM. TCM offers finer configuration for flexible transponders increasing SE, on 1.1dB wider ranges. TCM may also be used with HD-FEC in lower power transceivers.

Trellis modulation

Modulation (music)

Trellis (graph)

Transceiver

Constellation diagram

10.1364/ofc.2015.w3k.3

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Citations (14)