Sung Yun Lee

Seoul St. Mary's Hospital

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Seung Min Woo

Seoul St. Mary's Hospital

Seung Hyun Hong

Korea Research Institute of Bioscience and Biotechnology

Su Heui Lee

Korea Institute of Radiological and Medical Sciences

Chang Hak Yoo

Sungkyunkwan University

Duc Ky Lee

Seoul St. Mary's Hospital

Sae Jeong Yang

Seoul St. Mary's Hospital

Jang Wook Lee

National Fisheries Research and Development Institute

Byung Ik Kim

Sungkyunkwan University

Hong Ju Kim

Kangbuk Samsung Hospital

Kwan Joong Joo

Kangbuk Samsung Hospital

Cooperative Institutions

Seoul St. Mary's Hospital

Sungkyunkwan University

Kangbuk Samsung Hospital

Samsung Medical Center

Korea Institute of Radiological and Medical Sciences

Yonsei University

Korea University Medical Center

Inha University

CHA University

Elmhurst Hospital Center

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A Case of Fulminant Type 1 Diabetes Mellitus in an Elderly Patient

Journal of Korean Diabetes (2015)

Seung Min Woo Seung Hyun Hong Sung Yun Lee Su Heui Lee Duc Ky Lee

Insulin deficiency due to destruction of pancreatic β-cells is a typical characteristic of type 1 diabetes mellitus (DM). In 2000 Imagawa proposed a novel diagnostic model defining “fulminant type 1 DM” as developing rapidly without any evidence of autoimmunity, and ever since there have been many reports regarding the matter in Japan. In 2004, the first fulminant type 1 diabetes case was reported in Korea; however, there have been few reports since then. We present a case of a 60-year-old man who suffered from excessive thirst and polyuria after myalgia. Laboratory findings revealed a high blood glucose level and evidence of diabetic ketoacidosis, but the HbA1c level was within the normal range. The serum C-peptide level was very low and antibodies to glutamic acid decarboxylase were negative. These findings suggested fulminant type 1 diabetes. This patient has shown improvement in symptoms and examination results without complications after being treated with insulin therapy with hydration, throughout 6-months follow-up period.

Fulminant

Polyuria

Diabetic ketoacidosis

10.4093/jkd.2015.16.3.225

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Clostridium difficileColitis after Topical Ophthalmic Use of Levofloxacin

The Ewha Medical Journal (2013)

Jang Wook Lee Seong Yong Woo Suk Joon Park Seung Hyun Hong Sung Yun Lee

Clostridium difficile colitis (CDC) has been associated with virtually all available antibiotics. It is well known that administration of drugs by the ocular route can result in systemic absorption with the possibility of systemic effect. We report a case of a 74-year-old woman who was treated with 0.5% levofloxacin eyedrops for ten weeks running for the post operative management of two separate bilateral cataract surgeries. Toxin assay for C. difficile was positive and the endoscopic findings were compatible with CDC. The plasma concentrations reached after intraocular administration of levofloxacin seem so trivial, but the administration of topical agents could make accumulated effect and be a potential cause of systemic toxicity.

Clostridium Difficile Colitis

Systemic administration

Systemic antibiotics

10.12771/emj.2013.36.s.s5

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Multiple Metachronous Malignancies: One Patient with Five Primary Malignancies

Korean Journal of Medicine (2019)

Sung Yun Lee Byung Ik Kim Hong Ju Kim Kwan Joong Joo Sang‐Hyuk Lee

We report a case of a 73-year-old male with multiple, metachronous primary malignancies. He presented with adenocarcinoma of the stomach with transverse colon invasion followed by bladder cancer, hypopharyngeal cancer, urothelial cancer, and hepatocellular carcinoma, in that order, over 10 years. While these multiples malignancies were separate entities, they shared several etiologic factors, including smoking. To the best of our knowledge, this is the first description of five metachronous malignancies in a Korean patient. Keywords: Multiple malignancies; Metachronous; Cigarette smoking; Five primary malignancies ì¤ì¬ ë¨ì´: ë¤ë°ì± ì; ì´ìì±; í¡ì°; ë¤ì¯ê°ì§ ìë°ì± ì

Primary cancer

10.3904/kjm.2019.94.1.114

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