Mohammed Bakry

Benha University

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Mohammed Akhtar

Hamad Medical Corporation

Muhammad Ali

Peter MacCallum Cancer Centre

Kwesi Sackey

King Faisal Specialist Hospital & Research Centre

Rajeh Sabbah

King Faisal Specialist Hospital & Research Centre

Mohammed Ashraf Ali

Weatherford College

Mahmuda Huq

Queen's Hospital

Mohammed Akhtar

Imam Abdulrahman Bin Faisal University

Muhammad Ashraf Ali

King Faisal Specialist Hospital & Research Centre

Neelam Patel

The University of Texas MD Anderson Cancer Center

Anwaar Burgess

Riyadh Armed Forces Hospital

Cooperative Institutions

King Faisal Specialist Hospital & Research Centre

Fayoum University

NewYork–Presbyterian Brooklyn Methodist Hospital

King Fahd Security College

Benha University

Hamad General Hospital

Northern Border University

Hamad Medical Corporation

Creative Commons

Riyadh Armed Forces Hospital

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Fine-needle aspiration biopsy diagnosis of round cell malignant tumors of childhood. A combined light and electron microscopic approach

Cancer (1985)

Mohammed Akhtar Muhammad Ali Rajeh Sabbah Mohammed Bakry Joan E. Nash

A series of fine-needle aspiration biopsies (FNAB) from 76 children with round cell malignant tumors was studied by both light and electron microscopy. In 14 cases the material submitted for electron microscopy was inadequate, whereas in the remaining 62 biopsies a definitive diagnosis could be made. These included 29 malignant lymphomas, 8 neuroblastomas, 12 Ewing's sarcomas, 3 metastatic retinoblastomas, 3 Wilms' tumors, 3 rhabdomyosarcomas, and 4 unclassified tumors. The results from this study indicate that FNAB studied by light and electron microscopy can be effective in diagnosing small cell tumors in children.

10.1002/1097-0142(19850415)55:8<1805::aid-cncr2820550828>3.0.co;2-6

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Citations (87)

Dyspnea With Slow-Growing Mass of the Left Hemithorax

CHEST Journal (2007)

Neelam Patel Ayman Bishay Mohammed Bakry Liziamma George Anthony Saleh

Chest radiograph

Mediastinal mass

Mediastinal Shift

Left main bronchus

10.1378/chest.06-0485

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Citations (10)

Fine‐needle aspiration biopsy of pediatric neoplasms: Correlation between electron microscopy and immunocytochemistry in diagnosis and classification

Diagnostic Cytopathology (1992)

Mohammed Akhtar Carlos Bedrossian Muhammad Ali Mohammed Bakry

A series of fine-needle aspiration biopsies performed in 635 children were reviewed. The diagnoses rendered in these patients included malignant lymphoma in 139 (21.9%); Hodgkin's disease, 25 (3.9%); neuroblastoma, 58 (9.1%); Wilms' Tumor, 37 (5.8%); Ewing's sarcoma, 32 (5.0%); rhabdomyosarcoma, 25 (3.9%); retinoblastoma, 22 (3.5%); leukemia infiltrate, 33 (5.2%); and miscellaneous tumors, 52 (8.2%). In 171 patients (26.9%), the biopsy was nondiagnostic. The cytomorphological characteristics of these lesions are briefly described and illustrated. Salient morphological features are further correlated with histological and ultrastructural appearances. Immunocytochemical patterns of these tumors are also discussed briefly.

Cytopathology

Retinoblastoma

Aspiration biopsy

10.1002/dc.2840080314

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Citations (22)

Fine‐needle aspiration biopsy of seminoma and dysgerminoma: Cytologic, histologic, and electron microscopic correlations

Diagnostic Cytopathology (1990)

Mohammed Akhtar Mohammed Ashraf Ali Mahmuda Huq Mohammed Bakry

Abstract Cytomorphologic features in a series of fine‐needle aspiration biopsies from eight patients with seminoma or dysgerminoma were reviewed, and the findings were further correlated with histopathologic and ultrastructural appearances. Three cell types were encountered. Type I was least differentiated and least frequent. Type II was most frequent and had well‐developed cytoplasm rich in organelles. Type III was similar to type II but also contained abundant cytoplasmic glycogen. In cytology smears, type III cells contained large punched‐out cytoplasmic vacuoles corresponding to the areas of glycogen deposition. The background contained a variable mixture of inflammatory cells including lymphocytes, plasma cells, epithelioid cells, and epithelioid granulomas. The significance of these findings in the diagnosis of seminoma or dysgerminoma and the distinction from other germ‐cell and non‐germ‐cell tumors is briefly discussed.

Dysgerminoma

10.1002/dc.2840060206

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Citations (30)

Small round cell tumor with divergent differentiation: Cytologic, histologic, and ultrastructural findings

Diagnostic Cytopathology (1994)

Mohammed Akhtar Muhammad Ali Rajeh Sabbah Mohammed Bakry Fouad Al‐Dayel

Abstract A case study of desmoplastic small round cell tumor with divergent differentiation in a 13‐yr‐old boy is presented. Clinical, cytologic, histologic, immunohistochemical, and ultrastructural findings are reported. There was a close correlation between the various histologic and cytologic patterns. Immunohistochemical studies revealed strong positivity of many of the tumor cells for cytokeratin, vimentin, and desmin. Ultrastructurally, some of the tumor cells contained aggregates of cytoplasmic intermediate filaments. Fine‐needle aspiration biopsy may suggest the diagnosis of desmoplastic small round cell tumor. Confirmation of the diagnosis may be provided by immuhistochemistry and electronmicroscopy. Diagn Cytopathol 1994; 11:159–164. © 1994 Wiley‐Liss, Inc.

Desmin

Cytopathology

10.1002/dc.2840110210

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Citations (25)

Diagnostic accuracy of ovarian reserve markers in the differentiation between responders and non responders after laparoscopic ovarian drilling

The Egyptian Journal of Fertility of Sterility (2023)

Ahmed E. Abd El Tawwab Haitham Badran Abdelsamie A. Abdelsamie Mohammed Bakry

Ovarian Reserve

10.21608/egyfs.2023.297223

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Fine‐needle aspiration biopsy of langerhans histiocytosis (histiocytosis‐x)

Diagnostic Cytopathology (1993)

Mohammed Akhtar Muhammad Ashraf Ali Mohammed Bakry Kwesi Sackey Rajeh Sabbah

A series of 14 fine-needle aspiration biopsies (FNAB) from histologically proven cases of histiocytosis-x (Hx) were reviewed. The smears revealed a variable mixture of Langerhans cells, eosinophils, macrophages, polymorphonuclear cells, and giant cells. Based on the predominant cells present, the cases were further categorized as Langerhans cell predominant (nine cases), eosinophil predominant (two cases), and macrophage predominant (three cases). Langerhans cells were usually polygonal without significant evidence of phagocytosis and frequently contained indented nuclei. In three cases, several Langerhans cells showed prominent dendritic processes. Electron microscopy in 10 cases revealed Langerhans cells with varying degrees of morphologic differentiation. All cases studied revealed Birbeck granules. These findings indicate that FNAB may be an effective technique for diagnosing Hx.

Histiocytosis X

Langerhans Cell Histiocytosis

10.1002/dc.2840090511

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Citations (31)

Aspiration cytology of neuroblastoma: Light microscopy with transmission and scanning electron microscopic correlations

Diagnostic Cytopathology (1988)

Mohammed Akhtar Mohammed Ashraf Ali Kwesi Sackey Rajeh Sabbah Mohammed Bakry

Abstract Fine‐needle aspiration biopsies from three patients with neuroblastoma were studied by light microscopy, and the morphologic findings were correlated with those from transmission and scanning electron microscopy. Light microscopic examination of the aspiration smears from all three cases revealed small and large round cells with variable numbers of intertwining cytoplasmic processes. Transmission electron microscopy confirmed the light microscopic finding of cytoplasmic processes; in addition, it revealed the presence of other diagnostic morphologic features, including neurosecretory granules, microtubules, and synaptic cell junctions. Scanning electron microscopy demonstrated that the tumors were composed of a mixture of undifferentiated round cells and more differentiated cells with long cytoplasmic processes. The morphologic spectrum of these processes and their interrelationships with one another and with other cells could be studied in detail. These findings indicate that scanning electron microscopy may be used effectively in the morphologic evaluation and pathologic diagnosis of neuroblastoma.

10.1002/dc.2840040410

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Citations (10)

Fine Needle Aspiration Biopsy Diagnosis of Histiocytosis-X: A Brief Review

Annals of Saudi Medicine (1993)

Mohammed Akhtar Muhammad Ali Mohammed Bakry

Histiocytosis X

Eosinophilic granuloma

10.5144/0256-4947.1993.451

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Citations (1)

Neonatal Cord Blood PH versus Eucapnic PH as a Predictor for NICU Admission

Benha Medical Journal (2024)

Rasha Mohammed Zakaria Mohammed Bakry Zeinab El-Sayed Eman Abdelrahman

Background: For clinicians to determine the possibility for neonate brain damage and guide therapeutic decisions to avoid long-term complications, as cerebral palsy involving umbilical artery cord PH, base deficit, and lactic acid, the majority of biomarkers that are utilized for assessing fetal wellbeing, neonatal metabolic acidosis, and its associated complications in newborns are inaccurate and non-specific. On the other hand, the PHeucap demonstrates that it is the best biomarker and predictor for newborn metabolic acidosis and the obstacles that are associated with it. Aim: To evaluate the value of neonatal cord eucapnic PH in prediction of neonatal intensive care unit (NICU) admission in newborn subjected to perinatal asphyxia. Patients and methods: This prospective cohort investigation has been performed conducted on 40 newborns delivered at Benha university in Neonatal intensive care unit (NICU), from 1 March 2023 till 1 March 2024 who subjected to perinatal asphyxia and cord blood pH and eucapnic pH were measured and correlated with parameters of morbidity and mortality. Results: ROC analysis (Receiver operation Curve) showed that eucapnic PH had best prediction for NICU admission with sensitivity (90.91%) and specificity (58.62%) at cut-off point(7.03), while umbilical artery (UA)cord PH had sensitivity (63.64%) and specificity (55.85%)at cut-off point(6.85). a significant positive correlation has been detected between UA cord and pH euc-n and between pH euc-n and UAco2 with(r=0.369, P=0.019). (r=0.789, P

Umbilical artery

Cord blood

Perinatal asphyxia

Arterial pH

10.21608/bmfj.2024.324769.2214

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Citations (0)