Kurapati Sudhakar

New York Proton Center

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Arni S. R. Srinivasa Rao

Augusta University

Thomas Kurien

Nottingham University Hospitals NHS Trust

Steven G. Krantz

Washington University in St. Louis

Ramesh Bhat

University of Agricultural Sciences, Dharwad

Siddappa N. Byrareddy

University of Nebraska Medical Center

Kurien Thomas

Pondicherry Institute of Medical Sciences

David A. Swanson

The University of Texas MD Anderson Cancer Center

Michael B. Bonsall

University of Oxford

Emily Godbout

New York Proton Center

Philippe Saliou

Centre Hospitalier Régional Universitaire de Brest

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Communities In Schools of Orange County

203

New York Proton Center

197

Oregon Medical Research Center

191

Lindsay Unified School District

183

University of Richmond

178

Ann Arbor Center for Independent Living

175

University of Pittsburgh

Manhattan Institute for Policy Research

Centers for Disease Control and Prevention

Virginia Commonwealth University

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How relevant is the basic reproductive number computed during the coronavirus disease 2019 (COVID-19) pandemic, especially during lockdowns?

Infection Control and Hospital Epidemiology (2020)

Arni S. R. Srinivasa Rao Steven G. Krantz Michael B. Bonsall Thomas Kurien Siddappa N. Byrareddy

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Pandemic

2019-20 coronavirus outbreak

Coronavirus

Content (measure theory)

Basic reproduction number

10.1017/ice.2020.1376

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Citations (8)

ICE volume 43 issue 1 Cover and Front matter

Infection Control and Hospital Epidemiology (2022)

David P. Calfee David J. Weber Jaffar A. Al‐Tawfiq Hilary M. Babcock Kristina A. Bryant

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Front cover

Content (measure theory)

10.1017/ice.2022.11

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Strengthening India’s Response to HIV/AIDS Epidemic Through Strategic Planning, Innovative Financing, and Mathematical Modeling: Key Achievements over the Last 3 Decades

Journal of the Indian Institute of Science (2022)

Ramesh Bhat Kurapati Sudhakar Thomas Kurien Arni S. R. Srinivasa Rao

10.1007/s41745-022-00331-y

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Model-based retrospective estimates for COVID-19 or coronavirus in India: continued efforts required to contain the virus spread

Current Science (2020)

Arni S. R. Srinivasa Rao Steven G. Krantz Thomas Kurien Ramesh Bhat Kurapati Sudhakar

India reported having 498 cases COVID-19 (including 40 foreign tourists) as of 23 March 2020 (ref. 1) and out of which 32 cases were recovered and 9 deaths occurred. The number of COVID-19 cases worldwide as of 23 March 2020, was 378,000 with 16,500 deaths 2 . Overall more than 1.5 million passengers were screened at airports in India, 17,237 people were clinically tested for COVID-19 as of 22 March 2020 (ref. 1). Although the first case of COVID-19 was reported in India on 30 January 2020, for a student who has returned from Wuhan, China 3 , the confirmed cases started arising from the beginning of March. The government of India was quick to launch various levels of travel advisories beginning from 26 February 2020, with restrictions on travel to China and non-essential travel restrictions to Singapore, South Korea, Iran and Italy 3 .

2019-20 coronavirus outbreak

10.18520/cs/v118/i7/1023-1025

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Citations (20)

Antiretroviral Therapy and HIV Prevention in India: Modeling Costs and Consequences of Policy Options

Sexually Transmitted Diseases (2006)

Mead Over Elliot Marseille Kurapati Sudhakar Julian Gold Indrani Gupta

The objective of this study is to assess the costs, cost-effectiveness, and HIV epidemic impact of 3 antiretroviral therapy (ART) policy options.We constructed an epidemiologic model to predict the course of the HIV epidemic in the absence of expanded ART availability. Based on background studies of the willingness to pay for ART among patients with AIDS, of the costs to the government of the alternative treatment interventions, and of ART's likely effects on HIV transmission, we simulated the consequences of 3 possible alternative government ART policies.A program to reduce the negative consequences of the currently unstructured private-sector provision of ART is the most cost-effective of the 3 options at a 10% discount rate and least cost-effective at a 3% rate. The costs and cost-effectiveness of all options are highly sensitive to the effect of ART on condom use.The design of ART policy should capitalize on the potential of ART to decrease HIV transmission through institutional arrangements that reward effective prevention programs, thereby raising the likelihood that treatment has beneficial rather than negative external effects.

Treatment as prevention

10.1097/01.olq.0000238457.93426.0d

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Citations (37)

HIV/AIDS epidemic in India and predicting the impact of the national response: Mathematical modeling and analysis

Mathematical Biosciences & Engineering (2009)

Arni S. R. Srinivasa Rao Thomas Kurien Kurapati Sudhakar Philip K. Maini

After two phases of AIDS control activities in India, the third phase of the National AIDS Control Programme (NACP III) was launched in July 2007. Our focus here is to predict the number of people living with HIV/AIDS (PLHA) in India so that the results can assist the NACP III planning team to determine appropriate targets to be activated during the project period (2007-2012). We have constructed a dynamical model that captures the mixing patterns between susceptibles and infectives in both low-risk and high-risk groups in the population. Our aim is to project the HIV estimates by taking into account general interventions for susceptibles and additional interventions, such as targeted interventions among high risk groups, provision of anti-retroviral therapy, and behavior change among HIV-positive individuals. Continuing the current level of interventions in NACP II, the model estimates there will be 5.06 million PLHA by the end of 2011. If 50 percent of the targets in NACP III are achieved by the end of the above period then about 0.8 million new infections will be averted in that year. The current status of the epidemic appears to be less severe compared to the trend observed in the late 1990s. The projections based on the second phase and the third phase of the NACP indicate prevention programmes which are directed towards the general and high-risk populations, and HIV-positive individuals will determine the decline or stabilization of the epidemic. Model based results are derived separately for the revised HIV estimates released in 2007. According to revised projections there will be 2.08 million PLHA by 2012 if 50 percent of the targets in NACP III are reached. We perform a Monte Carlo procedure for sensitivity analysis of parameters and model validation. We also predict a positive role of implementation of anti-retroviral therapy treatment of 90 percent of the eligible people in the country. We present methods for obtaining disease progression parameters using convolution approaches. We also extend our models to age-structured populations.

10.3934/mbe.2009.6.779

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Citations (25)

Improvement in survival of people living with HIV/AIDS and requirement for 1st- and 2nd-line ART in India: a mathematical model

Notices of the American Mathematical Society (2012)

Arni S. R. Srinivasa Rao Kurien Thomas Kurapati Sudhakar RameshM Bhat

Line (geometry)

Source

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Citations (7)

Opinion

Notices of the American Mathematical Society (2012)

Arni S. R. Srinivasa Rao Kurien Thomas Kurapati Sudhakar Ramesh Bhat

10.1090/noti835

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Citations (2)