Joan Riera

Hospital Son Llatzer

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Franchek Drobnic

FC Barcelona

Adelina Pellicer

Hospital Universitario La Paz

Josep A. Tur

Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition

Antoni Pons

Universitat de les Illes Balears

Fernando Cabañas

Hospital Universitario Quirónsalud Madrid

María Carmen Bravo

Hospital Universitario La Paz

Antoni Sureda

Instituto de Salud Carlos III

Paloma López‐Ortego

Hospital Universitario La Paz

Rosário Madero

Hospital Universitario La Paz

Victoria Pons

Universidad de la República

Cooperative Institutions

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

Centro de Investigación Biomédica en Red

Instituto de Salud Carlos III

Universitat de Barcelona

Universidad Autónoma de Madrid

Universitat Autònoma de Barcelona

Hospital Universitario La Paz

Hospital Universitario de La Princesa

Hospital Universitari Germans Trias i Pujol

Hospital Sant Joan de Déu Barcelona

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Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm

Biomedical Optics Express (2011)

Simon Hyttel-Sørensen L C Sørensen Joan Riera Gorm Greisen

We compared absolute values of regional tissue hemoglobin saturation (StO(2)), reproducibility, and dynamic range of four different instruments on the forearm of adults. The sensors were repositioned 10 times on each subject. Dynamic range was estimated by exercise with subsequent arterial occlusion. Mean StO(2) was 70.1% ± 6.7 with INVOS 5100, 69.4% ± 5.0 with NIRO 200 NX, 63.4% ± 4.5 with NIRO 300, and 60.8% ± 3.6 with OxyPrem. The corresponding reproducibility S(w) was 5.4% (CI 4.4-6.9), 4.4% (CI 3.5-5.2), 4.1% (CI 3.3-4.9), and 2.7% (CI 2.2-3.2), respectively. The dynamic ranges ΔStO(2) were 45.0%, 46.8%, 44.8%, and 27.8%, respectively. In conclusion, the three commercial NIRS instruments showed different absolute values, whereas reproducibility and dynamic range were quite similar.

10.1364/boe.2.003047

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Citations (89)

Phase 1 study of two inodilators in neonates undergoing cardiovascular surgery

Pediatric Research (2012)

Adelina Pellicer Joan Riera Paloma López‐Ortego María Carmen Bravo Rosário Madero

Tolerability

Levosimendan

Regimen

10.1038/pr.2012.154

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Citations (49)

Effect of Acute Exposure to Moderate Altitude on Muscle Power: Hypobaric Hypoxia vs. Normobaric Hypoxia

PLoS ONE (2014)

Belén Feriche Amador García‐Ramos Carmen Calderón‐Soto Franchek Drobnic Juan Bonitch‐Góngora

When ascending to a higher altitude, changes in air density and oxygen levels affect the way in which explosive actions are executed. This study was designed to compare the effects of acute exposure to real or simulated moderate hypoxia on the dynamics of the force-velocity relationship observed in bench press exercise. Twenty-eight combat sports athletes were assigned to two groups and assessed on two separate occasions: G1 (n = 17) in conditions of normoxia (N1) and hypobaric hypoxia (HH) and G2 (n = 11) in conditions of normoxia (N2) and normobaric hypoxia (NH). Individual and complete force-velocity relationships in bench press were determined on each assessment day. For each exercise repetition, we obtained the mean and peak velocity and power shown by the athletes. Maximum power (Pmax) was recorded as the highest Pmean obtained across the complete force-velocity curve. Our findings indicate a significantly higher absolute load linked to Pmax (∼3%) and maximal strength (1RM) (∼6%) in G1 attributable to the climb to altitude (P<0.05). We also observed a stimulating effect of natural hypoxia on Pmean and Ppeak in the middle-high part of the curve (≥60 kg; P<0.01) and a 7.8% mean increase in barbell displacement velocity (P<0.001). No changes in any of the variables examined were observed in G2. According to these data, we can state that acute exposure to natural moderate altitude as opposed to simulated normobaric hypoxia leads to gains in 1RM, movement velocity and power during the execution of a force-velocity curve in bench press.

Hypoxia

Altitude sickness

10.1371/journal.pone.0114072

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Citations (31)

Cardiorespiratory parameters during submaximal exercise under acute exposure to normobaric and hypobaric hypoxia

Apunts Medicina de l Esport (2012)

Carla Basualto-Alarcón Gil Rodas Pedro A. Galilea Joan Riera Teresa Pagés

Hypoxia

Hypobaric chamber

Respiratory Rate

Acute exposure

10.1016/j.apunts.2011.11.005

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Citations (33)

New developments in cerebral blood flow autoregulation analysis in preterm infants: a mechanistic approach

Pediatric Research (2015)

Joan Riera Fernando Cabañas José Javier Serrano Olmedo Rosário Madero Adelina Pellicer

Cerebral autoregulation

10.1038/pr.2015.231

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Citations (17)

Exercise in a hot environment influences plasma anti-inflammatory and antioxidant status in well-trained athletes

Journal of Thermal Biology (2014)

Antoni Sureda Antonia Mestre-Alfaro Montserrat Banquells Joan Riera Franchek Drobnic

10.1016/j.jtherbio.2014.11.011

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Citations (36)

Calorie restriction regime enhances physical performance of trained athletes

Journal of the International Society of Sports Nutrition (2018)

Victoria Pons Joan Riera Xavier Capó Miquel Martorell Antoni Sureda

Background Caloric restriction induces mitochondrial biogenesis and improves physical fitness in rodents. We aimed to provide evidence of how caloric restriction affects the body composition and physical performance of trained athletes and to evaluate the possible impact of an every-other-day feeding diet on nutritional deficiencies of micronutrients and essential fatty acids.Methods The study was performed with 12 healthy male athletes by carrying out a 33% caloric restriction with respect to their usual diet. Athletes performed a maximal exercise stress test both before and after the caloric restriction period. Blood samples were taken before and after the caloric restriction at basal conditions and 30 min post-exercise. Although energy intake was reduced by about 33%, the contribution of carbohydrates, proteins, and lipids to total energy intake during the caloric restriction was similar to the original diet.Results The caloric restriction reduced the daily specific micronutrient intake to values lower than 90% of recommended dietary allowances. No effects were observed in blood parameters related to iron metabolism and tissue damage, glucose levels, lipid profiles, or erythrocyte fatty acid composition. In addition, oxidative damage markers decreased after the nutritional intervention. The caloric restriction intervention significantly reduced body weight and trunk, arm, and leg weights; it also caused a decrease in fat and lean body mass, the energy expenditure rate when performing a maximal exercise stress test, and the energy cost to run one meter at various exercise intensities. Furthermore, the intervention ameliorated the onset of the anaerobic phase of exercise.Conclusion A caloric restriction improves athletes’ performance and energy efficiency, but reduces the daily intake of micronutrients; so, when caloric restriction programs are implemented micronutrient supplementation should be considered.Trial registration The project was registered at ClinicalTrials.gov (NCT02533479).

Caloric theory

Calorie Restriction

Calorie

10.1186/s12970-018-0214-2

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Citations (33)

The SafeBoosC phase II clinical trial: an analysis of the interventions related with the oximeter readings

Archives of Disease in Childhood Fetal & Neonatal (2015)

Joan Riera Simon Hyttel-Sørensen María Carmen Bravo Fernando Cabañas Paloma López‐Ortego

Background

The SafeBoosC phase II randomised clinical trial recently demonstrated the benefits of a combination of cerebral regional tissue oxygen saturation (rStO₂) by near-infrared spectroscopy (NIRS) and a treatment guideline to reduce the oxygen imbalance in extremely preterm infants.

Aims

To analyse rStO₂-alarm-related clinical decisions and their heterogeneity in the NIRS experimental group (NIRS monitoring visible) and their impact on rStO₂ and SpO₂.

Methods

Continuous data from NIRS devices and the alarms (area under the curve of the rStO₂ out of range had accumulated 0.2%h during 10 min), clinical data at discrete time points and interventions prompted by the alarms were recorded.

Results

Sixty-seven infants had data that fulfilled the requirements for this analysis. 1107 alarm episodes were analysed. The alarm triggered a treatment guideline intervention in 25% of the cases; the type of intervention chosen varied among clinical sites. More than 55% of alarms were not followed by an intervention ('No action'); additionally, in 5% of alarms the rStO₂ value apparently was considered non-reliable and the sensor was repositioned. The percentage of unresolved alarms at 30 min after 'No action' almost doubled the treatment guideline intervention (p<0.001). Changes in peripheral oxygen saturation (SpO₂), were observed only after treatment guideline interventions.

Conclusions

This study shows that 25% of rStO₂ alarms were followed by a clinical intervention determined by the treatment guideline. However, the rStO₂ and SpO₂ returned to normal ranges after the intervention, supporting the notion that decisions taken by the clinicians were appropriate.