The general purpose of this thesis is to establish the ability of Speckle Tracking Echocardiography (STE) in assessing left atrial (LA) response to pressure and volume overload respectively in aort ...

Volume overload

Pressure overload

Speckle tracking echocardiography

Left atrial pressure

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Right Ventricular Longitudinal Strain and Right Ventricular Stroke Work Index in Patients With Severe Heart Failure: Left Ventricular Assist Device Suitability for Transplant Candidates

Transplantation Proceedings (2012)

Matteo Cameli Sonia Bernazzali Matteo Lisi Charilaos Tsioulpas M.G. Croccia

Speckle tracking echocardiography

Cardiac index

10.1016/j.transproceed.2012.06.018

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Citations (55)

Reference Values of Right Atrial Longitudinal Strain Imaging by Two‐Dimensional Speckle Tracking

Echocardiography (2011)

Margherita Padeletti Matteo Cameli Matteo Lisi A. Malandrino Valerio Zacà

The role of speckle tracking in the assessment of right atrial (RA) deformation dynamics has not been established yet. The reference ranges of RA longitudinal strain indices were measured by speckle tracking in a population of normal subjects.In 84 healthy individuals, peak atrial longitudinal strain (PALS), peak atrial contraction strain (PACS), and time to peak longitudinal strain (TPLS) were measured using a six-segment model for the RA. Strain rate (SR) was also measured starting from the QRS-wave onset, peak positive (x-wave), first peak negative (y-wave), and second negative peak (z-wave). The time from the QRS onset was measured to each wave peak.Adequate tracking quality was achieved in 64% of segments analyzed. Inter- and intraobserver variability coefficients of measurements ranged between 6% and 11%. Global PALS was 49 ± 13%, global TPLS was 363 ± 59 msec, x-wave was 2.12 ± 0.58 sec(-1) , y-wave was -1.91 ± 0.63 sec(-1) , and z-wave was -2.18 ± 0.78 sec(-1) .Speckle tracking is a feasible technique for the assessment of longitudinal myocardial RA deformation. Reference ranges of strain indices were reported.

Strain (injury)

Tracking (education)

P wave

Speckle tracking echocardiography

10.1111/j.1540-8175.2011.01564.x

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Citations (91)

Predictors of hypercontractile heart phenotype in patients with chronic coronary syndromes or heart failure

Research Square (Research Square) (2024)

Yi Wang Quirino Ciampi Lauro Cortigiani A Zagatina Jarosław D. Kasprzak

Abstract Background Hypercontractile phenotype (HP) of the left ventricle (LV) is an actionable therapeutic target in patients with chronic coronary syndromes (CCS) or heart failure (HF), but its clinical recognition remains difficult. Objectives To assess the clinical variables associated with the HP. Methods In a prospective, observational, multicenter study, we recruited 5,122 patients (age 65 ± 11 years, 2974 males, 58%) with CCS and/or HF with preserved ejection fraction (EF). Systolic blood pressure (SBP) was measured. We assessed wall motion score index (WMSI), LV end-diastolic volume (EDV), end-systolic volume (ESV), EF, force (SBP/ESV), stroke volume (SV), arterial elastance (SBP/SV), and ventricular-arterial coupling (VAC, as SV/ESV). Univariable and multivariable logistic regression analysis assessed independent factors associated with the highest force sextile. Results For all the studied patients, force was 4.51 ± 2.11 mmHg/ml, with the highest sextile (Group 6) > 6.36 mmHg/ml. By multivariable logistic regression model, the highest sextile of force was associated with age > 65 years (OR 1.62, 95% CI 1.36–1.93, p < 0.001), hypertension (OR 1.76, 95% CI 1.40–2.21, p < 0.001), female sex (OR 4.52, 95% CI 3.77–5.42, p < 0.001), absence of beta-blocker therapy (OR 1.41, 95% CI 1.16–1.68), rest SBP ≥ 160 mmHg (OR 2.81, 95% CI 2.21–3.56, p < 0.001), high heart rate (OR 2.08, 95% CI 1.61–2.67, p < 0.001), and absence of prior myocardial infarction (OR 1.34, 95% CI 1.07–1.68, p = 0.012). Patients in the highest sextile of force showed lower values of WMSI, SV, EDV, and ESV, and higher values of arterial elastance and VAC. Conclusions HP of the LV with high force was clinically associated with advanced age, female sex, high resting SBP, and the absence of 𝛽-blocker therapy. By transthoracic echocardiography, HP was associated with a small heart with reduced EDV, reduced SV despite high EF, and higher arterial elastance.

10.21203/rs.3.rs-4476811/v1

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Prognostic value of left atrial strain in patients with moderate asymptomatic mitral regurgitation

The International Journal of Cardiovascular Imaging (2019)

Matteo Cameli Maria Concetta Pastore Francesca Maria Righini Giulia Elena Mandoli Flavio D’Ascenzi

Subclinical infection

Speckle tracking echocardiography

10.1007/s10554-019-01598-6

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Citations (45)

Severity of aortic stenosis predicts early post-operative normalization of left atrial size and function detected by myocardial strain