Tianlu Zhang

Institute of Process Engineering

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Zhiguo Lü

Northeastern University

Jie Shen

Institute of Physics

Xin Zhang

Institute of Process Engineering

Yunwei Niu

Shanghai Institute of Technology

Jianze Wang

Sichuan University

Jun Yang

Institute of Process Engineering

Zuobing Xiao

Shanghai Institute of Technology

Xin Zhang

Southwest University

Ruichen Zhao

University of Chinese Academy of Sciences

Zuobing Xiao

Shanghai Institute of Technology

Cooperative Institutions

Chinese Academy of Sciences

University of Chinese Academy of Sciences

Wuhan University

Chinese Academy of Medical Sciences & Peking Union Medical College

Institute of Process Engineering

Zhengzhou University

Renmin Hospital of Wuhan University

Peking University

Sichuan University

Shanghai Jiao Tong University

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Unsupervised Patch-GAN with Targeted Patch Ranking for Fine-Grained Novelty Detection in Medical Imaging

arXiv (Cornell University) (2025)

Jingkun Chen Guang Yang Xiaoli Zhang Jingchao Peng Tianlu Zhang

Detecting novel anomalies in medical imaging is challenging due to the limited availability of labeled data for rare abnormalities, which often display high variability and subtlety. This challenge is further compounded when small abnormal regions are embedded within larger normal areas, as whole-image predictions frequently overlook these subtle deviations. To address these issues, we propose an unsupervised Patch-GAN framework designed to detect and localize anomalies by capturing both local detail and global structure. Our framework first reconstructs masked images to learn fine-grained, normal-specific features, allowing for enhanced sensitivity to minor deviations from normality. By dividing these reconstructed images into patches and assessing the authenticity of each patch, our approach identifies anomalies at a more granular level, overcoming the limitations of whole-image evaluation. Additionally, a patch-ranking mechanism prioritizes regions with higher abnormal scores, reinforcing the alignment between local patch discrepancies and the global image context. Experimental results on the ISIC 2016 skin lesion and BraTS 2019 brain tumor datasets validate our framework's effectiveness, achieving AUCs of 95.79% and 96.05%, respectively, and outperforming three state-of-the-art baselines.

Novelty Detection

10.48550/arxiv.2501.17906

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Preparation of Photo-Responsive Nanomicelles Loaded with Sandela 803 for Wallpaper Application

Nanoscience and Nanotechnology Letters (2019)

Tianlu Zhang Zhiguo Lü Jie Shen Jing Hu Yunwei Niu

Wallpaper

10.1166/nnl.2019.2856

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Citations (1)

Preparation of polymer nano-fragrance: a review

Scientia Sinica Chimica (2018)

Jie Shen Hongxia Lu Zhiguo Lü Tianlu Zhang Weihong Zhu

As a sort of fine chemicals, fragrance has many different kinds and functions, and has been widely filtered into various fields in our life. However, main components of fragrance are volatile substances with low boiling point, which makes fragrance hard to retain and sensitive to circumstances. Thus, the scope of fragrance is limited. An effective way to prolong the retention and improve the stability of fragrance is to prepare fragrance in nano-scale and build sustained-controlled release systems by polymer materials. In this review, we summarized the recent progress in preparation of polymer nano-fragrance.

10.1360/n032018-00195

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Citations (1)

Micro-displacement Amplifying Mechanism of a Piezoelectric Single Crystal Actuator and Its Motion Characterization

2022 IEEE International Conference on Mechatronics and Automation (ICMA) (2020)

Tianlu Zhang Zhangming Du Chao Zhou Zhiqiang Cao Shuo Wang

Piezoelectric single crystal actuator is useful in the micro- and nano-scaled. But the range of the operation is limited. The paper presented the amplifying mechanism of the single crystal actuator in order to amplify the output of the piezoelectric actuator in micro- and nano-applications. Due to the single crystal's expansion when the applied signals decrease, the paper developed the adjustable spring that added to the amplifying mechanism. This paper tested the characteristics of the amplifying mechanism by designed a set of experiment device. The input and output displacement of the amplifying mechanism driven by kinds of signals were measured. It can concluded that the amplifying mechanism achieve the positive and negative displacement response and show its accuracy and stable. These excellent properties of the amplifying mechanism amplify the micro-displacement and expand the operating range of single crystal actuator in micro- and nano-positioning applications.

Crystal (programming language)

10.1109/icma49215.2020.9233763

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生物启发和生物工程核酸药物载体

Science China Materials (2024)

Jiamin Zuo Zhiguo Lü Jing Guo Ruichen Zhao Tianlu Zhang

10.1007/s40843-024-2858-8

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The application of photo-sensitive nano fragrance on wallpaper

Scientia Sinica Chimica (2018)

Jie Shen Hongxia Lu Zhiguo Lü Tianlu Zhang Zuobing Xiao

In this article, the mesoporous silica nanocolumns were prepared via sol-gel method.The photo-sensitive small molecules were coupled with mesoporous silica nanocolumns during the preparation of these nanoparticles.With the higher surface area and pore volume, plenty of sandela 803 was encapsulated in the photo-sensitive mesoporous silica nanocolumns to form the nano fragrance, which was then applied to wallpaper.Finally, the release profiles of wallpaper treated nano fragrance were detected by gas chromatography.The results show that the wallpaper-treated nano fragrance could release sandela 803 slowly in the dark and controllably in the light.

Wallpaper

10.1360/n032018-00194

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Synthesis and characterization of novel biocompatible nanocapsules encapsulated lily fragrance

Chinese Chemical Letters (2018)

Weihong Ji Tianlu Zhang Zhiguo Lü Jie Shen Zuobing Xiao

Nanocapsules

Biocompatibility

Biocompatible material

Encapsulation

10.1016/j.cclet.2018.09.008

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Citations (15)

Piezoelectric Single Crystal-based Nano-scale Actuator and Its Amplifying Mechanism

2022 IEEE International Conference on Mechatronics and Automation (ICMA) (2019)

Tianlu Zhang Zhangming Du Chao Zhou Zhiqiang Cao Shuo Wang

Actuator is the key technology of the micro-nano robots and operations. The piezoelectric single crystal is a new choice compared with the traditional piezoelectric ceramic actuator. The paper designed a set of performance test device to measure PZN-5.5% PT single crystal actuator's characteristics. The actuator show the good linearity and negligible hysteresis, which can reduce the complex of the system and improve the response speed. The paper also developed a flexible hinge amplifying mechanism to improve the range of the displacement. An adjustable spring mechanism was optimally developed for pre-load to achieve negative displacement response. Subsequently the simulated and mathematical magnification ratio was compared with experimental data. And the mechanism was measured. The steady and accurate outputs of the system validated that the amplifying mechanism can amplify the input displacement at voltage drive.

Hysteresis

Linearity

10.1109/icma.2019.8816464

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Citations (2)

A charge-amplifier based self-sensing method for measurement of piezoelectric displacement

2022 IEEE International Conference on Mechatronics and Automation (ICMA) (2017)

Zhangming Du Tianlu Zhang Lu Deng Chao Zhou Zhiqiang Cao

Manipulation in nano-scale is important to the development of Nano-technology, while position sensing is the base of nano-manipulation. Self-sensing is a method providing true sensor-actuator collocation and especially suitable for room-limited workspace. This paper introduced a self-sensing method for displacement measurement, based on charge amplifier. The principle of self-sensing was derived from piezoelectric constitutive equations, and a charge amplifier circuit was developed to obtain the displacement of piezoelectric stack. A series of experiments were conducted to evaluate the characteristics of our method. The results of the experiments and some characteristics of charge-amplifier based self-sensing method were presented.

Charge amplifier

10.1109/icma.2017.8016124

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Citations (8)

Preparation of mesoporous silica nanoparticle with tunable pore diameters for encapsulating and slowly releasing eugenol

Chinese Chemical Letters (2021)

Tianlu Zhang Zhiguo Lü Jianze Wang Jie Shen Qiulian Hao

Volatilisation

10.1016/j.cclet.2020.12.033

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Citations (25)