Irene López Rojo

MD Anderson Cancer Center Madrid

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Santiago González‐Moreno

MD Anderson Cancer Center Madrid

Gloria Ortega Pérez

Universidade Federal Fluminense

Damián García‐Olmo

Hospital Universitario Fundación Jiménez Díaz

ÓA

Óscar Alonso Casado

MD Anderson Cancer Center Madrid

Patricia Tejedor

Hospital General Universitario Gregorio Marañón

Joaquín Gómez Ramírez

Instituto Cajal

Elena Hurtado

Hospital General Universitario Gregorio Marañón

Lorena Brandáriz

Comunidad de Madrid

Santiago López‐Ben

Hospital Universitari de Girona Doctor Josep Trueta

T. Villegas

Hospital Universitario Virgen de las Nieves

Cooperative Institutions

MD Anderson Cancer Center Madrid

Hospital Universitario Fundación Jiménez Díaz

Universidad Autónoma de Madrid

Hospital General Universitario Gregorio Marañón

The University of Texas MD Anderson Cancer Center

Hospital Universitario Ramón y Cajal

Universitat de Barcelona

Hospital Universitario La Paz

Hospital Clínico San Carlos

Clinica Universidad de Navarra

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Breast adenocarcinoma over fibroadenoma. When the pathological report is not as expected.

European Journal of Surgical Oncology (2022)

Santiago González‐Moreno Irene López Rojo Gloria Ortega Pérez Jacobo Cabañas Montero Alejandro Rojo Sebastián

Apocrine

Papillomatosis

Metaplasia

Ectasia

10.1016/j.ejso.2021.12.061

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Citations (0)

Sclerosing angiomatoid nodular transformation (SANT), a rare splenic tumor with increasing incidence

Revista Española de Enfermedades Digestivas (2023)

Irene López Rojo A. Quintáns Raquel Saiz Martínez Patricia Muñoz Hernández Ó. Alonso-Casado

SANT (sclerosing angiomatoid nodular transformation) tumor is a rare splenic tumor of unknown etiology and vascular lineage, first described in 2004. Most cases are asymptomatic, although cases of anemia or abdominal pain in association with growth have been described. Spontaneous ruptures have not been described. Radiologically it presents a radial pattern with centripetal filling in dynamic MRI, being a characteristic feature, but not pathognomonic. It may present hypermetabolism in PET-CT. Its incidence is increasing since its description as an independent clinical and histopathological entity, especially in the oncological patients follow-up. Due to its radiological resemblance to metastatic lesions and its growth despite being a vascular lesion, splenectomy is indicated following the principles of oncologic surgery until a definitive diagnosis is made. It presents a benign behavior, requiring neither treatment nor specific subsequent surveillance. Two diagnosed cases of SANT are presented, as well as a review of the clinical, radiological and histopathological characteristics of this little-known splenic lesion.

Pathognomonic

Hypermetabolism

Etiology

10.17235/reed.2023.9713/2023

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Perioperative management of non-deferrable oncologic surgeries during COVID-19 pandemic in Madrid, Spain. Is it safe?

Revista Española de Anestesiología y Reanimación (English Edition) (2022)

Javier Galipienzo R.J. Otta-Oshiro Débora Berdecio Salvatierra Cristina Laura Casado Medrano Irene López Rojo

Pandemic

Isolation

10.1016/j.redare.2021.03.005

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Citations (1)

Incidencia y seguimiento a 5 años de la recidiva locorregional durante 4 años consecutivos en una unidad multidisciplinar de patología mamaria

Revista de Senología y Patología Mamaria (2015)

S Salido Patricia Tejedor Irene López Rojo Alicia Cazorla Olivia Benítez Dupin

10.1016/j.senol.2015.04.004

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Ibero-American Consensus for the Management of Peritoneal Sarcomatosis: Updated Review and Clinical Recommendations

Cancers (2024)

F.C. Muñoz-Casares Javier Martín‐Broto Pedro Antonio Cáscales-Campos J Torres-Melero Irene López Rojo

Peritoneal sarcomatosis is a rare malignant disease with a poor prognosis, secondary to peritoneal dissemination of abdominopelvic soft tissue sarcomas. Its rarity, together with the characteristic histological heterogeneity and the historically poor response to systemic treatments, has prevented the establishment of widely accepted treatment criteria with curative intent. In this sense, radical cytoreductive surgery (CRS) with peritonectomy procedures and hyperthermic intraperitoneal chemotherapy (HIPEC), widely used in peritoneal carcinomatosis with excellent results, have not had the same evolutionary development in patients with peritoneal sarcomatosis. A multidisciplinary working group of experts in sarcomas and peritoneal oncological surgery established a series of recommendations based on current scientific evidence for the management of peritoneal sarcomatosis, taking into account the different histological subgroups of abdominopelvic sarcomas that can cause it depending on their origin: retroperitoneal sarcomas, uterine sarcomas, and visceral/peritoneal sarcomas of GIST (gastrointestinal stromal tumor) and non-GIST origin. This article shows the results of sarcoma experts' voting on the recommendations presented during the I Ibero-American Consensus on the Management of Peritoneal Sarcomatosis, which took place during the recent celebration of the III Hispanic-Portuguese Meeting for Updates on the Treatment of Sarcomas.

Hyperthermic Intraperitoneal Chemotherapy

10.3390/cancers16152646

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Priorización, selección de pacientes y manejo multimodal perioperatorio del cáncer colorrectal en situación de colapso del sistema sanitario

Cirugía y Cirujanos (2021)

Irene López Rojo Oscar Alonso Gloria Ortega‐Pérez Javier Galipienzo-García Santiago González‐Moreno

The aim is to analyze the usefulness of pre-operative COVID-19 screening to detect asymptomatic patients, the capability of our patient selection algorithm to detect patients with more advanced tumors and the results of colorectal cancer surgery managed with a multimodal approach. We propose the use of a preoperative patient selection algorithm to prioritize the surgical treatment of patients with worse oncological prognosis and lower perioperative risk in situations of health system saturation.Prospective descriptive study including 71 patients operated on for colorectal cancer during COVID-19's high incidence period. A division was made into two periods of time that were later compared with the aim of assessing whether the scale used identified those patients with lower surgical risk and higher oncological priority for their priority scheduling.Post-operative severe acute respiratory syndrome coronavirus 2 infection occurred in one patient (1.4%). Pre-operative polymerase chain reaction detected one asymptomatic patient (3%). Tumor stage was ≥ IIIA in 39% and node positive in 39% of patients in the first period, while 26% and 21% in the second period, respectively (p = 0.320; p = 0.179), without increasing the surgical stay or complications. Median hospital stay was 5 days. Grades III and IV morbidity were 4.4% and 1.4%.The use of an algorithm and Patient Selection Scale can detect patients with more advanced tumors to be operated before. Multimodal management/ERAS have a role in achieving short stay and low morbidity.El retraso terapéutico derivado de la saturación del Sistema sanitario conlleva un peor pronóstico oncológico y un aumento de complicaciones en el cáncer colorrectal. Proponemos el usode un algoritmo de selección de pacientes de forma preoperatoria para priorizar el tratamiento quirúrgico de los pacientes con peor pronóstico oncológico y menor riesgo perioperatorio.Realizamos un estudio descriptivo prospectivo de 71 pacientes intervenidos por cáncer colorrectal durante el periodo de máxima incidencia por COVID. Se realizó una división en dos periodos de tiempo que fueron comparados posteriormente con el objetivo de valorar si la escala utilizada conseguía identificar aquellos pacientes con menor riesgo quirúrgico y mayor prioridad oncológica para su programación prioritaria.Utilizando la escala de priorización de pacientes (PSS) observamos que el estadio tumoral fue mayor de IIIA en un 39% de los pacientes con un 39% de ganglios positivos en un primer periodo, frente a un 26% y 21% en un segundo periodo (p = 0.320; p = 0.179) de tiempo, sin aumentar la estancia operatoria ni las complicaciones. Se realizaron dos métodos de cribado de COVID-19 en dos periodos de tiempo, detectando un 3% de pacientes asintomáticos de forma preoperatoria con PCR, y documentando un 1.4% de infección por COVID postoperatoria.Ante la saturación del sistema sanitario, la utilización de protocolos y algoritmos para selección de pacientes con cáncer colorrectal puede ayudar a dar preferencia quirúrgica a aquellos casos que no deben ser demorados.

10.24875/ciru.20000990

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Intestinal mucormycosis as a differential diagnosis of small bowel ischemia

Revista Española de Enfermedades Digestivas (2024)

Irene López Rojo Esther Martin Illana Laura Castella Bataller Santiago González‐Moreno Ó. Alonso-Casado

Intestinal mucormycosis is a rare manifestation of the Mucor fungus, associated with high mortality and typically found in immunocompromised patients, though it has also been described in immunocompetent individuals. The mode of acquisition is digestive. It usually presents as abdominal pain, with ischemia and intestinal perforation, and the diagnosis is often histopathological after surgical resection. We present the case of a 54-year-old female patient with recurrent acute myeloid leukemia undergoing treatment with daunorubicin-cytarabine and experiencing febrile neutropenia. She developed patchy and progressive intestinal ischemia that evolved into intestinal necrosis, which was treated with antifungal medications and surgery. Examination of the surgical specimen revealed aseptate wide hyphae with branching at right angles, suggestive of Mucor fungus. This is a rare but highly mortal pathology in which clinical, radiological, and surgical suspicion is essential for early diagnosis and treatment, thus improving the patient's prognosis.

Perforation

10.17235/reed.2024.10630/2024

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Cohort profile: the Spanish Early-onset Colorectal Cancer (SECOC) cohort: a multicentre cohort study on the molecular basis of colorectal cancer among young individuals in Spain

BMJ Open (2021)

José Perea Marc Martí Eloy Espín Sergio Hernández‐Villafranca Pilar Orihuela

Purpose The Spanish Early-onset Colorectal Cancer (SECOC) study is a multicentre prospective cohort established in Spain to investigate the molecular basis of early-onset colorectal cancer (EOCRC), including metabolic alterations. Participants 220 patients with EOCRC have been enrolled since January 2019 through 18 centres across Spain. Individual-level data were collected by questionnaire, including lifestyle and other colorectal cancer-related factors. Medical record review was performed to capture clinical, histopathological and familial cancer history data. Biospecimen collection (blood, stool, tissue) at diagnosis and at various time points across treatment, as applicable, is also completed. Findings to date Participants had a median age of 44 years (range 14–49), and the majority are men (60%), with individuals age 40–49 years at EOCRC diagnosis being over-represented. Forty-three per cent of participants were diagnosed with a tumour in the rectosigmoid junction/rectum. Nearly two-thirds of EOCRC cases (64%) were diagnosed with advanced stage (III–IV) disease, and 28% of cases had no reported familial history of cancer. Future plans We are actively recruiting and observing participants; we plan to administer follow-up questionnaires and perform additional biospecimen collection. This prospective cohort offers a unique, rich resource for research on EOCRC aetiologies and will contribute to larger international efforts to disentangle the rising disease burden.

10.1136/bmjopen-2021-055409

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Citations (8)

Arterial embolization does not decrease morbidity after distal pancreatectomy plus celiac trunk resection: A Spanish muticentre study

HPB (2020)

José Manuel Ramia E. Vicente Fernando Pardo Lídia Sabater Santiago López‐Ben

Distal pancreatectomy

10.1016/j.hpb.2020.04.059

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Radioguided surgery, a useful tool for the surgical oncologist

European Journal of Surgical Oncology (2022)