Yanqi Xie

Second Affiliated Hospital of Zhejiang University

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Weizhi Zhu

Dalian University of Technology

Youqiong Wang

Guangxi Medical University

Jiangfeng Li

First Affiliated Hospital Zhejiang University

Guobin Weng

Ningbo No. 2 Hospital

Yalong Wang

Sun Yat-sen University

Xueyou Ma

Zhejiang University

Xiao Wang

First Affiliated Hospital of Wenzhou Medical University

Ben Liu

First Affiliated Hospital Zhejiang University

Huizhi Huang

Anhui Medical University

Xiuhua You

Fujian Medical University

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Sun Yat-sen University

Zhejiang University

First Affiliated Hospital Zhejiang University

Ningbo No. 2 Hospital

Institute of Pharmacology

The First Affiliated Hospital, Sun Yat-sen University

Sichuan University

Sichuan Agricultural University

Guangxi University

Huazhong University of Science and Technology

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A prospective multi-center randomized comparative trial evaluating outcomes of transrectal ultrasound (TRUS)-guided 12-core systematic biopsy, mpMRI-targeted 12-core biopsy, and artificial intelligence ultrasound of prostate (AIUSP) 6-core targeted biopsy for prostate cancer diagnosis

World Journal of Urology (2022)

Xiao Wang Yanqi Xie Xiangyi Zheng Ben Liu Hong Chen

Prostate biopsy

10.1007/s00345-022-04086-0

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Determination of neuroprotective oxysterols in Calculus bovis, human gallstones, and traditional Chinese medicine preparations by liquid chromatography with mass spectrometry

Journal of Separation Science (2014)

Yalong Wang Han Jiang Huizhi Huang Yanqi Xie Yunshi Zhao

So far, the components responsible for the neuroprotective effects of Calculus bovis are unclear. Cholesterol, one of the major components in Calculus bovis , is easily oxidized into oxysterols, which possess direct or indirect neuroprotective effects proved by our and others’ previous studies. Therefore, a liquid chromatography with mass spectrometry method coupled with ultrasonic extraction and solid‐phase extraction was developed for the determination of neuroprotective oxysterols in Calculus bovis , human gallstones, and traditional Chinese medicine preparations. Chromatographic separation was achieved on a C 18 column with isocratic elution at a flow rate of 1 mL/min. The established method showed good linearity ( R 2 > 0.998), sensitivity with low limits of detection (0.06–0.39 μg/g), acceptable precisions (relative standard deviations ≤ 7.4%), stability (relative standard deviations ≤ 5.9%), and satisfactory accuracy (92.4–102.9%) for all analytes identified by different retention times, which could be applied for the determination of oxysterols. Five kinds of oxysterols proved to function as neuroprotectants were detected at different concentrations. Among them, 7β‐hydroxycholesterol and cholestane‐3β,5α,6β‐triol were rather abundant in the samples. It could be concluded that the potential neuroprotective components in Calculus bovis may be these oxysterols.

10.1002/jssc.201400850

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Citations (9)

SEMISYNTHETIC AURONES: A FAMILY OF NEWLY DISCOVERED TUBULIN INHIBITORS AS ANTINEOPLASTIC AGENTS

Yanqi Xie

10.13023/etd.2019.387

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Internal Fusion: exact correlation of transrectal ultrasound images of the prostate by detailed landmarks over time for targeted biopsies or follow-up

World Journal of Urology (2017)

Yanqi Xie Theodoros Tokas Björn Grabski Tillmann Loch

Nephrology

Prostate biopsy

10.1007/s00345-017-2161-y

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Citations (6)