To get an optimal product of orthopaedic implant or regenerative medicine needs to follow trial-and-error analyses to investigate suitable product's material, structure, mechanical properites etc. The whole process from in vivo tests to clinical trials is expensive and time-consuming. Computational model is seen as a useful analysis tool to make the product development. A series of models for simulating tissue engineering process from cell attachment to tissue regeneration are reviewed. The challenging is that models for simulating tissue engineering processes are developed separately. From cell to tissue regeneration, it would go through blood injection after moving out the defect; to cell disperse and attach on the scaffold; to proliferation, migration and differentiation; and to the final part-becoming mature tissues. This paper reviewed models that related to tissue engineering process, aiming to provide an opportunity for researchers to develop a mature model for whole tissue engineering process. This article focuses on the model analysis methods of cell adhesion, nutrient transport and cell proliferation, differentiation and migration in tissue engineering. In cell adhesion model, one of the most accurate method is to use discrete phase model to govern cell movement and use Stanton-Rutland model for simulating cell attachment. As for nutrient transport model, numerical model coupling with volume of fluid model and species transport model together is suitable for predicting nutrient transport process. For cell proliferation, differentiation and migration, finite element method with random-walk algorithm is one the most advanced way to simulate these processes. Most of the model analysis methods require further experiments to verify the accuracy and effectiveness. Due to the lack of technology to detect the rate of nutrient diffusion, there are especially few researches on model analysis methods in the area of blood coagulation. Therefore, there is still a lot of work to be done in the research of the whole process model method of tissue engineering. In the future, the numerical model would be seen as an optimal way to investigate tissue engineering products bioperformance and also enable to optimize the parameters and material types of the tissue engineering products.
In this study, an innovative exploration of leveraging bionics and continuum robotics principles to develop a novel solution for arthroscopic surgery is embarked on. Inspired by the flexibility and adaptability of organisms like snakes and octopuses, the continuum robot concept aims to address the inherent challenges in traditional arthroscopy, including lower precision, manual tremors, and long surgeon learning curves. The implementation of these principles in the human body, however, faces significant obstacles, particularly achieving high‐performance motion control amid strong nonlinearity and coupling between modules. This research focuses on intelligent integration and enhanced safety in human‐machine interaction, aiming for improved control precision and flexibility in arthroscopic procedures. A thorough literature review of endoscopic continuum robots is conducted, highlighting current advancements in actuation, structure, sensing, and control technologies. The study concludes with an assessment of these technologies, their limitations, and future potential, in light of the unique demands of arthroscopic continuum robots. This comprehensive review bridges bionics and robotics, presenting the opportunities and challenges in applying continuum robotics to arthroscopic surgery. The goal is to encourage further research in this area, contributing to the development of prototype robots that enhance the precision and safety of arthroscopic surgery.
We demonstrate a three-axis atomic magnetometer with one intensity-modulated pump beam and one orthogonal probe beam. The main field component is measured using the resonance of the pumping light, while the transverse field components are measured simultaneously using the optical rotation of the probe beam modulated by the spin precession. It is an all-optical magnetometer without using any modulation field or radio frequency field. Magnetic field sensitivity of 0.8 pT/Hz1∕2 is achieved under a bias field of 2 μT.
Indirect method combined with homotopy approach is used to solve low-thrust fuel-optimal problem. To start the homotopy progress, pseudospectral method is used to solve energy-optimal problem to generate the initial guess. The proposed approach is applied to Earth to a near earth asteroid rendezvous mission. The performance of such approach is demonstrated through simulation.
Increasing demand for higher power, lighter weight and compact power generation systems in aircraft has resulted in the need for a new high temperature insulation system. It requires better thermal capability and improved reliability over the 240°C system used commercially. A 280°C insulation system has been developed based on a hybrid organic-inorganic material to address these evolving requirements. This electrical insulation system comprises a nanocomposite polyimide wire for windings, and a hybrid slot liner for ground wall insulation. Thermal, electrical and mechanical properties of this insulation system will be discussed.
The design of the space hatch door mechanisms is crucial in the aerospace field, impacting not only durability and reliability but also the life safety of astronauts during space missions. This review extensively researches vehicle doors and hatches in civil and military systems across various environments, including land, sea, deep sea, aviation, aerospace, and extreme conditions. Specially, it focuses on the structural design of hatches and related mechanisms in civil aviation and military aerospace environments, such as opening and closing mechanisms, release mechanisms, locking mechanisms, sealing mechanisms, and the ergonomic design of door structures. The review highlights the integration of bionic design principles with hatch mechanisms to explore future solutions. By systematically examining these aeras, this review addresses the lack of comprehensive studies in previous reviews, which often overlook the interconnectivity and applicability of hatch mechanisms across different fields. The absence of such holistic reviews has led to fragmented knowledge and missed opportunities for cross-industry innovation. This review aims to fill these gaps by providing a wide range of design solutions and offering insights that can enhance the development of more reliable, efficient, and safe hatch mechanisms in aerospace and other high-stakes environments.
With the rapid proliferation of mobile devices, mobile commerce is widely considered to be a driving force for next-generation e-commerce. Mobile commerce application has attracted the attention of both practitioners and academics. This paper analyzes the diffusion of mobile commerce applications using a new classification scheme that based on the perspective of market. This classification - mobile communication service, mobile information service, mobile transaction service and mobile interaction service, reflects the diffusion of mobile commerce application in the market. It will provide useful insights into the anatomy of mobile commerce application and help us find and design new mobile applications. We also provide some recommendations for future research into mobile commerce applications.
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