Claudia Gagnon

Université Laval

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Peter R. Ebeling

Monash University

Anne‐Sophie Morisset

Université Laval

André Marette

Institut Universitaire de Cardiologie et de Pneumologie de Québec

Anne‐Marie Carreau

Université Laval

André Tchernof

Université Laval

Robin M. Daly

Deakin University

Fabrice Mac‐Way

Hôtel-Dieu de Québec

Marie‐Claude Vohl

Université Laval

Anne‐Frédérique Turcotte

Université Laval

S. John Weisnagel

Université Laval

Cooperative Institutions

Université Laval

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Centre hospitalier universitaire de Québec

Université de Montréal

Institut Universitaire de Cardiologie et de Pneumologie de Québec

McGill University

Centre hospitalier de l'Université Laval

Université de Sherbrooke

University of Toronto

McMaster University

Montreal Heart Institute

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Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Advances in Nutrition (2018)

Sarah O’Connor Anne‐Frédérique Turcotte Claudia Gagnon Iwona Rudkowska

Glycated hemoglobin

10.1093/advances/nmy074

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Citations (30)

Concerns about recommending over-the-counter drugs to treat helminthiasis.

PubMed (1999)

Claudia Gagnon

Over-the-counter

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Do pregnant women eat healthier than non-pregnant women of childbearing age?

Figshare (2020)

Claudia Savard Anne-Sophie Plante Élise Carbonneau Claudia Gagnon Julie Robitaille

We aimed to compare the dietary quality and intake of pregnant women, women planning to conceive and women of childbearing age. Fifty-five pregnant women were matched for age and pre-pregnancy body mass index with 55 women planning to conceive and 55 women of childbearing age. Three Web-based 24-h recalls were completed, from which the Canadian Healthy Eating Index was calculated. Pregnant women had greater overall diet quality scores (66.8 ± 10.7, 60.3 ± 14.1 and 61.4 ± 12.8, in pregnant vs. planning to conceive and childbearing age women, p = .009), explained by a higher intake in fruits, vegetables and grain products and lower intake of foods that are high in fat, sugar or salt. Energy intake was significantly higher in pregnant versus planning to conceive women only (2283 ± 518 vs. 2062 ± 430 kcal, p = .03). Diet quality was greater among pregnant women, but diet quality scores were low in all groups, indicating that healthier dietary behaviours should be encouraged for all childbearing age women.

10.6084/m9.figshare.11814423

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Prevalence and determinants of hypertension in the adult Inuit population of Nunavik (northern Quebec, Canada)

Can J Public Health (2023)

Janie Allaire Benoît Lévesque Paul Poirier Claudia Gagnon Geneviève Auclair

Abstract Objectives To assess the prevalence of arterial hypertension among Inuit adults living in Nunavik (northern Quebec, Canada) in 2017 and identify its sociodemographic and lifestyle determinants. Methods We used data obtained from 1177 Inuit adults aged ≥ 18 years who participated in the cross-sectional Qanuilirpitaa? Nunavik Inuit Health Survey during late summer-early fall of 2017. Resting blood pressure (BP) and anthropometric characteristics were measured during a clinical session, while sociodemographic characteristics and lifestyle habits were documented using validated questionnaires. Information on current medication was retrieved from medical files. Sex-stratified population-weighted log-binomial regressions were conducted to identify determinants of hypertension, adjusting for potential confounders. Results Hypertension (systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mmHg or taking antihypertensive medication) was present in 23% of the adult population and was more frequent in men than women (29% vs. 18%). About a third of hypertensive individuals (34%) were taking antihypertensive medication. These estimates are prone to biases due to the relatively low participation rate (37%). As expected, the prevalence of hypertension increased with age, but values were surprisingly elevated in 18 to 29-year-old men and women (18% and 8%, respectively) compared with 20 to 39-year-old adults of the general Canadian population (3% in both sexes, according to data from the Canadian Health Measures Survey, 2012–2015). Hypertension was associated with obesity and alcohol consumption in both men and women, and with higher socioeconomic status among men. Conclusion This survey revealed a high prevalence of hypertension among young Nunavimmiut adults in 2017 and the need to improve hypertension diagnosis and treatment in the region. Curbing obesity and alcohol consumption, two actionable determinants of hypertension, will require improving food security and addressing the consequences of historical trauma linked to colonization.

Cross-sectional study

10.17269/s41997-023-00774-5

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Claudia Gagnon

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Reduced Intestinal Calcium Absorption Correlates With Bone Loss After Sleeve Gastrectomy: Implications for Clinical Care

The Journal of Clinical Endocrinology & Metabolism (2022)

Claudia Gagnon

Journal Article Reduced Intestinal Calcium Absorption Correlates With Bone Loss After Sleeve Gastrectomy: Implications for Clinical Care Get access Claudia Gagnon Claudia Gagnon CHU de Québec-Université Laval Research Centre, Quebec City, QC G1V 4G2, CanadaQuebec Heart and Lung Institute Research Centre, Quebec City, QC G1V4 4G5, CanadaDepartment of Medicine, Université Laval, Quebec City, QC, G1V 0A6CanadaService of Endocrinology, CHU de Québec-Université Laval, Québec City, QC G1V 4G2, Canada Correspondence: Claudia Gagnon, MD, CHU de Québec-Université Laval Research Centre, 2705 Boulevard Laurier, Quebec City, QC, Canada, G1V 4G2. Email: claudia.gagnon@crchudequebec.ulaval.ca. https://orcid.org/0000-0001-9623-962X Search for other works by this author on: Oxford Academic Google Scholar The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 3, March 2023, Pages e32–e33, https://doi.org/10.1210/clinem/dgac681 Published: 24 November 2022 Article history Received: 09 November 2022 Editorial decision: 20 November 2022 Published: 24 November 2022 Corrected and typeset: 14 December 2022

10.1210/clinem/dgac681

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Hyperglycemia Worsens Gut Bacterial Infection Through Intestinal Wnt, But Independent of Endotoxemia or Obesity

Arshpreet Bhatwa Trevor C. Lau Joseph B. McPhee Fernando F. Anhê Gabriel Forato Anhê

10.2139/ssrn.4934080

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Prevalence of Vertebral Fractures in Adults With Type 1 Diabetes: DenSiFy Study (Diabetes Spine Fractures)

The Journal of Clinical Endocrinology & Metabolism (2022)

Julie-Catherine Coll Élodie Garceau William D. Leslie Mathieu Genest Laëtitia Michou

Abstract Context Vertebral fracture (VF) prevalence up to 24% has been reported among young people with type 1 diabetes (T1D). If this high prevalence is confirmed, individuals with T1D could benefit from preventative VF screening. Objective We compared the prevalence of VFs between adults with T1D and nondiabetic controls. Methods This cross-sectional study included 127 adults with T1D, and 65 controls with a similar age, sex, and BMI distribution, from outpatient clinics of 2 tertiary care centers. Vertebral fracture assessment (VFA) by dual-energy x-ray absorptiometry (DXA) was used for prevalent VFs. The modified algorithm-based qualitative (mABQ) method was applied. Bone mineral density (BMD) and trabecular bone score (TBS) were assessed by DXA. Serum bone turnover markers and sclerostin were measured in a subgroup of participants. Results Participants with T1D (70 women, 57 men) had a mean age of 42.8 ± 14.8 years, median diabetes duration of 25.8 (15.8-34.4) years, mean BMI of 26.6 ± 5.4 kg/m2 and mean HbA1c over the past 3 years of 7.5 ± 0.9%. Controls (35 women, 30 men) had mean age of 42.2 ± 15.9 years and mean BMI of 26.1 ± 5.1 kg/m2. VF prevalence was comparable between groups (2.4% vs 3.1%, P = 0.99). TBS, BMD at the total hip and femoral neck, and bone formation and resorption markers were lower while sclerostin levels were similar in participants with T1D vs controls. Conclusion Our VFA results using the mABQ method do not confirm increased prevalence of VFs in men and women with relatively well-controlled T1D.

Sclerostin

Dual-Energy X-ray Absorptiometry

10.1210/clinem/dgac031

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Substituting refined sugars with maple syrup decreases key cardiometabolic risk factors in individuals with mild metabolic alterations: a randomized, double-blind, controlled crossover trial

Journal of Nutrition (2024)

Arianne Morissette Anne-Laure Agrinier Théo Gignac Lamia Ramadan Khoudia Diop

Crossover study

10.1016/j.tjnut.2024.08.014

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Palopegteriparatide Treatment Improves Renal Function in Adults with Chronic Hypoparathyroidism: 1-Year Results from the Phase 3 PaTHway Trial

Advances in Therapy (2024)

Lars Rejnmark Elvira O. Gosmanova Aliya Khan Noriko Makita Yasuo Imanishi

Individuals with chronic hypoparathyroidism managed with conventional therapy (active vitamin D and calcium) have an increased risk for renal dysfunction versus age- and sex-matched controls. Treatments that replace the physiologic effects of parathyroid hormone (PTH) while reducing the need for conventional therapy may help prevent a decline in renal function in this population. This post hoc analysis examined the impact of palopegteriparatide treatment on renal function in adults with chronic hypoparathyroidism.

Hypoparathyroidism

Post-hoc analysis

10.1007/s12325-024-02843-8

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Citations (5)