Andreja Rajković

Ghent University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Mieke Uyttendaele

Ghent University

Frank Devlieghere

Ghent University

NŠ

Nada Šmigić

University of Belgrade

Johan Debevere

Ghent University

Marc Heyndrickx

Ghent University

IĐ

Ilija Đjekić

University of Belgrade

Nikola Tomić

University of Belgrade

Božidar Udovički

University of Belgrade

Charlotte Grootaert

Ghent University

Tom Van de Wiele

Ghent University

Cooperative Institutions

Ghent University

183

Ghent University Hospital

University of Belgrade

KU Leuven

Sciensano (Belgium)

University of Belgrade – Faculty of Chemistry

Zhejiang University

Wageningen University & Research

Institut Scientifique de Santé Publique

Centre National de la Recherche Scientifique

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Global Burden of Colistin-Resistant Bacteria: Mobilized Colistin Resistance Genes Study (1980–2018)

Microorganisms (2019)

Mohammed Elbediwi Yan Li Narayan Paudyal Hang Pan Xiaoliang Li

Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The recent global dissemination of mobilized colistin resistance (mcr) genes is an urgent public health threat. An accurate estimate of the global prevalence of mcr genes, their reservoirs and the potential pathways for human transmission are required to implement control and prevention strategies, yet such data are lacking. Publications from four English (PubMed, Scopus, the Cochrane Database of Systematic Reviews and Web of Science) and two Chinese (CNKI and WANFANG) databases published between 18 November 2015 and 30 December 2018 were identified. In this systematic review and meta-analysis, the prevalence of mcr genes in bacteria isolated from humans, animals, the environment and food products were investigated. A total of 974 publications were identified. 202 observational studies were included in the systematic review and 71 in the meta-analysis. mcr genes were reported from 47 countries across six continents and the overall average prevalence was 4.7% (0.1-9.3%). China reported the highest number of mcr-positive strains. Pathogenic Escherichia coli (54%), isolated from animals (52%) and harboring an IncI2 plasmid (34%) were the bacteria with highest prevalence of mcr genes. The estimated prevalence of mcr-1 pathogenic E. coli was higher in food-animals than in humans and food products, which suggests a role for foodborne transmission. This study provides a comprehensive assessment of prevalence of the mcr gene by source, organism, genotype and type of plasmid.

Colistin

10.3390/microorganisms7100461

Cite

Citations (225)

Bacillus cereus food intoxication and toxicoinfection

Comprehensive Reviews in Food Science and Food Safety (2021)

Jelena Jovanović Vincent Ornelis Annemieke Madder Andreja Rajković

Abstract Bacillus cereus is one of the leading etiological agents of toxin‐induced foodborne diseases. Its omnipresence in different environments, spore formation, and its ability to adapt to varying conditions and produce harmful toxins make this pathogen a health hazard that should not be underestimated. Food poisoning by B. cereus can manifest itself as an emetic or diarrheal syndrome. The former is caused by the release of the potent peptide toxin cereulide, whereas the latter is the result of proteinaceous enterotoxins (e.g., hemolysin BL, nonhemolytic enterotoxin, and cytotoxin K). The final harmful effect is not only toxin and strain dependent, but is also affected by the stress responses, accessory virulence factors, and phenotypic properties under extrinsic, intrinsic, and explicit food conditions and host‐related environment. Infamous portrait of B. cereus as a foodborne pathogen, as well as a causative agent of nongastrointestinal infections and even nosocomial complications, has inspired vast volumes of multidisciplinary research in food and clinical domains. As a result, extensive original data became available asking for a new, both broad and deep, multifaceted look into the current state‐of‐the art regarding the role of B. cereus in food safety. In this review, we first provide an overview of the latest knowledge on B. cereus toxins and accessory virulence factors. Second, we describe the novel taxonomy and some of the most pertinent phenotypic characteristics of B. cereus related to food safety. We link these aspects to toxin production, overall pathogenesis, and interactions with its human host. Then we reflect on the prevalence of different toxinotypes in foods opening the scene for epidemiological aspects of B. cereus foodborne diseases and methods available to prevent food poisoning including overview of the different available methods to detect B. cereus and its toxins.

10.1111/1541-4337.12785

Cite

Citations (143)

Computer aided boar semen motility analysis for cereulide detection in different food matrices

International Journal of Food Microbiology (2006)

Andreja Rajković Mieke Uyttendaele Johan Debevere

BOAR

10.1016/j.ijfoodmicro.2006.09.031

Cite

Citations (38)

New Insights into the Potential Cytotoxic Role of Bacillus cytotoxicus Cytotoxin K-1

Toxins (2021)

Klèma Marcel Koné Pauline Hinnekens Jelena Jovanović Andreja Rajković Jacques Mahillon

The thermotolerant representative of the

Wild type

10.3390/toxins13100698

Cite

Citations (8)

Inactivation of foodborne pathogens on leek and alfalfa seeds with supercritical carbon dioxide

The Journal of Supercritical Fluids (2021)

Siméon Bourdoux Alessandro Zambon Inge Van der Linden Sara Spilimbergo Frank Devlieghere

Supercritical Carbon Dioxide

10.1016/j.supflu.2021.105433

Cite

Citations (8)

Monitoring Heat Stable Intoxicative Enterotoxins of Bacillus cereus Staphylococcus aureus in Food. Oral Communication

Andreja Rajković Mieke Uyttendaele Johan Debevere

Food poisoning

Bacillus (shape)

Source

Cite

Citations (0)

Regulation of toxin production by Bacillus cereus and its food safety implications

Critical Reviews in Microbiology (2011)

Siele Ceuppens Andreja Rajković Marc Heyndrickx Varvara Tsilia Tom Van de Wiele

Toxin expression is of utmost importance for the food-borne pathogen B. cereus, both in food poisoning and non-gastrointestinal host infections as well as in interbacterial competition. Therefore it is no surprise that the toxin gene expression is tightly regulated by various internal and environmental signals. An overview of the current knowledge regarding emetic and diarrheal toxin transcription and expression is presented in this review. The food safety aspects and management tools such as temperature control, food preservatives and modified atmosphere packaging are discussed specifically for B. cereus emetic and diarrheal toxin production.

Cereus

Food poisoning

Food Preservatives

10.3109/1040841x.2011.558832

Cite

Citations (138)

Uticaj pogonskih laboratorija na poboljšanje kvaliteta prehrambenih proizvoda : osvrt na stanje u prehrambenoj industriji Srbije

Ilija Đjekić Nada Šmigić Radomir Radovanović Andreja Rajković

Source

Cite

Citations (0)

Contemporary strategies in combating microbial contamination in food chain