Aim: We investigated the relationship between mild renal dysfunction (MRD) and the presence of coronary artery disease (CAD) in people under 60 years of age. Materials & methods: A total of 634 (317 patients with vessel stenosis ≥50% and 317 with normal angiography) individuals diagnosed with stable angina pectoris and estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m2 were included in the present study. Results: The mean eGFR was lower (95.3 ± 23.7 vs 109.7 ± 22.3, respectively, p = 0.002) and the number of patients with MRD was higher in patients with CAD (137, 43.2%) than in the control group (52, 16.4%, p < 0.001). The multivariate analysis showed that lower eGFR is an independent risk factor for presence of CAD in people under 60 years of age with stable angina pectoris. Conclusion: According to our retrospective study, the risk of developing CAD appears to be slightly increased in individuals under 60 years of age with MRD.
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Gül İ, Küçükdurmaz Z, Kalay N, et al. Polymorphisms of some increased cardiovascular risk related genes in acute coronary syndromes and their relation to coronary artery disease severity. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2012;8(1):25-30. doi:10.5114/pwki.2012.27922. APA Gül, İ., Küçükdurmaz, Z., Kalay, N., Karapinar, H., İnanç, M., & Özdoğru, İ. et al. (2012). Polymorphisms of some increased cardiovascular risk related genes in acute coronary syndromes and their relation to coronary artery disease severity. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 8(1), 25-30. https://doi.org/10.5114/pwki.2012.27922 Chicago Gül, İbrahim, Zekeriya Küçükdurmaz, Nihat Kalay, Hekim Karapinar, Mehmet Tuğrul İnanç, İbrahim Özdoğru, and Ahmet Yilmaz et al. 2012. "Polymorphisms of some increased cardiovascular risk related genes in acute coronary syndromes and their relation to coronary artery disease severity". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 8 (1): 25-30. doi:10.5114/pwki.2012.27922. Harvard Gül, İ., Küçükdurmaz, Z., Kalay, N., Karapinar, H., İnanç, M., Özdoğru, İ., Yilmaz, A., and Kemal Eryol, N. (2012). Polymorphisms of some increased cardiovascular risk related genes in acute coronary syndromes and their relation to coronary artery disease severity. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 8(1), pp.25-30. https://doi.org/10.5114/pwki.2012.27922 MLA Gül, İbrahim et al. "Polymorphisms of some increased cardiovascular risk related genes in acute coronary syndromes and their relation to coronary artery disease severity." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 8, no. 1, 2012, pp. 25-30. doi:10.5114/pwki.2012.27922. Vancouver Gül İ, Küçükdurmaz Z, Kalay N, Karapinar H, İnanç M, Özdoğru İ et al. Polymorphisms of some increased cardiovascular risk related genes in acute coronary syndromes and their relation to coronary artery disease severity. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2012;8(1):25-30. doi:10.5114/pwki.2012.27922.
Prostetik kapak trombozu hayati tehdit eden onemli bir komplikasyondur. Genellikle uygunsuzantikoagulan kullanimi sonucu gorulmektedir. Prostetik kapak trombozunda tercih edilen tedavicerrahidir. Sol taraf prostetik kapak trombozunda trombolitik tedavi; cerrahi girisim yuksek risklioldugunda ve trombus nispeten kucuk oldugunda ilk tedavi secenegi olarak dusunulebilir. Bu olgu,tekrarlayan prostetik kapak trombozunda t-PA tedavisinin basarisini gostermektedir
Brachial artery endothelial dysfunction was shown previously in a small group of Behçet's disease (BD) patients. This study aimed to compare the endothelial function in BD patients with and without vascular involvement. The study group consisted of 25 BD patients with vascular involvement, 25 BD patients without any vascular disease and 46 healthy controls. Brachial artery flow-mediated (endothelium-dependent) dilation (FMD), nitroglycerine-induced dilation and carotid artery intima-media thickness were measured. FMD was impaired in patients with BD (10.41 +/- 3.85%) compared to healthy controls (14.41 +/- 3.39%, p < 0.001). FMD was significantly lower in BD patients with vascular involvement (8.80 +/- 3.63%) than those without any vascular disease (12.02 +/- 3.43%, p = 0.003). This study reveals that endothelial dysfunction documented by brachial artery FMD is a feature of BD, and it is more prominent in patients with vascular involvement.
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