H. A. Da Silva

University of Rochester

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William W. Brennessel

University of Rochester

Brandon R. Barnett

University of Rochester

Sérgio Bertazzo

University College London

Willian F. Zambuzzi

Universidade Estadual Paulista (Unesp)

Shane S. Michtavy

University of Rochester

Carmen V. Ferreira

Universidade Estadual de Campinas (UNICAMP)

Celso A. Bertran

Universidade Estadual de Campinas (UNICAMP)

Bevan S. Whitehead

University of Rochester

Jaehwan Kim

Cornell University

Phillip J. Milner

Cornell University

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University of Rochester

Universidade Estadual de Campinas (UNICAMP)

Cornell University

University of California, Berkeley

Lawrence Berkeley National Laboratory

University of California System

Universidade de Mogi das Cruzes

Ithaca College

Columbia University

Parkwood Hospital

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Bioactivation of alumina by surface modification: a possibility for improving the applicability of alumina in bone and oral repair

Clinical Oral Implants Research (2009)

Sérgio Bertazzo Willian Fernando Zambuzzi H. A. Da Silva Carmen V. Ferreira Celso A. Bertran

Abstract Objectives: In regenerative medicine, surface engineering of bioinert synthetic materials is often required in order to introduce bioactive species that can promote cell adhesion, proliferation, viability and enhanced ECM‐secretion functions. The aim of this work is to study cell interaction with alumina‐modified surfaces. Material and methods: In this work, chemical properties of alumina surface were changed by a reaction at the surface of alumina with low molecular weight dicarboxylic acid, which produced carboxyl groups. Results: These carboxyl groups were able to complex with Ca 2+ on the surface, forming sites of precipitation for calcium phosphates that make alumina biocompatible, as indicated by cell culture of pre‐osteoblasts (MC3T3‐E1 cell line). Conclusions: The procedure presented in this work shows that the insertion of specific functional groups on the surface of alumina increases cell interaction with the surface of alumina. This knowledge can be important in oral science and orthopedics, for the construction of prosthesis.

Surface Modification

Biocompatible material

10.1111/j.1600-0501.2008.01642.x

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Citations (54)

Selective Adsorption of the Super Greenhouse Gas Tetrafluoromethane within a Metal–Organic Framework with Dynamic Corrugated Ultramicropores

Bevan S. Whitehead William W. Brennessel Shane S. Michtavy H. A. Da Silva Jaehwan Kim

Perfluorocompound (PFC) gases play vital roles in microelectronics processing. Requirements for ulta-high purities traditionally necessitate use of virgin sources and thereby hinder the capture, purification, and reuse of these costly gases. Most importantly, gaseous PFCs are incredibly potent greenhouse gases with atmospheric lifetimes on the order of 103-104 years, and thus any environmental emissions have an outsized and prolonged impact on our climate. The development of sorbents that can capture PFC gases from industrial waste streams has lagged substantially behind the progress made over the last decade in capturing CO2 from both point emission sources and directly from air. Herein, we show that the metal–organic framework Zn(fba) (fba2– = 4,4’-(hexafluoroisopropylidene)bis-benzoate) displays an equilibrium selectivity for CF4 adsorption over N2 that surpasses those of all water-stable sorbents that have been reported for this separation. This selectivity is enabled by adsorption within narrow corrugated channels lined with ligand-based aryl rings, a site within this material that has not previously been realized as being accessible to guests. Analyses of adsorption kinetics and X-ray diffraction data are used to characterize sorption and diffusion of small adsorbates within these channels and strongly implicate rotation of the linker aryl rings as a gate that modulates transport of CF4 through a crystallite. Multi-component breakthrough measurements demonstrate that Zn(fba) is able to resolve CF4 and N2 under flowing mixed-gas conditions. Taken together, this work illuminates a more complete picture of the dynamic structure of Zn(fba), and also points toward general design principles that can enable large CF4 selectivities in sorbents with more favorable kinetic profiles.

10.26434/chemrxiv-2023-9vrz0

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Citations (1)