Xue-Song Xiang

Chinese Center For Disease Control and Prevention

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Wenbin Zhang

Nanjing Brain Hospital

Rui Cao

Nanchang University

Feng Wang

Guangdong Academy of Medical Sciences

Dongyun Li

Seventh People's Hospital of Dalian

Shuang-Bin Gao

Air Force Medical University

Xiaoming Ying

Taizhou First People's Hospital

Jiajia Zhao

Shanxi Agricultural University

Qingxia Li

Hebei Medical University

Yingjie Tian

Inner Mongolia People's Hospital

Zechen Zhang

Hebei Medical University

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Air Force Medical University

Taizhou First People's Hospital

Nanjing Medical University

Hebei Medical University

Nanjing Brain Hospital

Xinjiang Medical University

First Affiliated Hospital of Xinjiang Medical University

Chinese People's Armed Police Force

Logistics University of People's Armed Police Force

Ministry of Education of the People's Republic of China

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Intracerebroventricular administration of conjugated linoleic acid (CLA) inhibits food intake by decreasing gene expression of NPY and AgRP

Neuroscience Letters (2007)

Zipeng Cao Feng Wang Xue-Song Xiang Rui Cao Wenbin Zhang

10.1016/j.neulet.2007.03.010

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Citations (41)

[Relationship between rs2282679 gene locus polymorphism and vitamin D deficiency in college students].

PubMed (2020)

Yingjie Tian Xue-Song Xiang Xiaoming Ying Dongyun Li Jiajia Zhao

To investigate the relationship between vitamin D binding protein gene rs2282679 A/C polymorphism with blood vitamin D levels.A total of 286 eligible subjects were selected from one university in Hebei Province. Serum 25-hydroxylated vitamin D levels were measured by liquid chromatography-mass spectrometry, and gene chip was used for genotyping of rs2282679 locus. Statistical analysis was performed using R software.A total of 285 participants in the study completed the experiment, and result indicated that the distribution of the rs2282679 locus A/C polymorphism in the participants was consistent with the Hardy-Weinberg equilibrium. The genotype of rs2282679 was significantly associated with serum vitamin D insufficiency and deficiency(P=0. 031). Allele A was a risk factor for vitamin D insufficiency and deficiency. The OR value of allele C relative to A was 0. 65, and the genetic pattern of allele C relative to A was dominant(P=0. 03).The vitamin D-binding protein gene rs2282679 was significantly associated with serum vitamin D insufficiency and deficiency in college students, and A-allele is a risk factor accounting for vitamin D insufficiency and deficiency in college students.

Vitamin D-binding protein

Gene polymorphism

Hardy–Weinberg principle

10.19813/j.cnki.weishengyanjiu.2020.06.009

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