New!Keep up with current practice guidelines and policies with the latest, most up-to-date edition of this clinical reference classic. This evidence-based decision-making tool for managing common pediatric conditions has been revised and updated for 2014, with the latest clinical practice guidelines for more than 30 conditions, plus every AAP policy statement, clinical report, and technical report through December 2013.Updated and expanded for 2014 including:- Three new AAP clinical practice guidelines- Management of Newly Diagnosed Type 2 Diabetes Mellitus- Diagnosis and Management of Acute Bacterial Sinusitis in Children Aged 1 to 18 Years- Diagnosis and Management of Acute Otitis Media- New Periodicity Schedule- Full text of more than 60 new or revised AAP policies- CD-ROM includes the full text of more than 400 AAP clinical practice guidelines, policy statements, clinical reports, and technical reports.- More than 30 clinical practice guidelines including Sleep Apnea, ADHD, bronchiolitis, dysplasia of the hip, gastroenteritis, otitis media, urinary tract infection and more.- 2014 immunization schedule.

10.1542/9781581108613-part05-phototherapy

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Citations (7)

The Jaundiced Newborn in the Emergency Department: Prevention of Kernicterus

Clinical Pediatric Emergency Medicine (2008)

Vinod K. Bhutani Lois Johnson

Kernicterus

Exchange transfusion

Irritability

Coma (optics)

10.1016/j.cpem.2008.06.004

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Citations (3)

141 Total bilirubin rate of rise of in moderate preterm neonates: impact of gestational age

Paediatrics & Child Health (2019)

Thivia Jegathesan Vinod K. Bhutani Douglas M. Campbell Vibhuti Shah Jennifer Twiss

Abstract Background As compared to term neonates, those < 35 weeks gestation (wks GA) are at greater risk for both acute and chronic bilirubin encephalopathy (ABE, CBE). Among these with postnatal total bilirubin rate of rise, (TB ROR) at age 0 to 72 hours has been observed because of either loss placental elimination system or increased postnatal production due to hemolysis. The ranges are known to vary > 8.5 umol/L/h in neonates with Rh disease to >3.4 umol/L/h at the 95th percentile track of the hour-specific nomogram. TB ROR in healthy term neonates is <3.4 umol/L/h. Objectives To determine the GA ranges on TB ROR to explore predictive TB ROR in preterm neonates who are more vulnerable with each <35 wks GA. Design/Methods A multi-site observational study to quantify TB ROR in preterm infants between 28 to 35 weeks. 1804 infants born between January 2013- March 2018 at 28–35 wks GA from three canadian perinatal centres were included and those with Rh disease were excluded. Analysis included infants >27 weeks with at least one TB prior to the initiation of treatment for severe hyperbilirubinemia treatment. Feeding patterns, birth history and maternal health conditions were documented. Results The TB ROR were compared by two prematurity GA groups (28–31 weeks and 32–35 weeks) then per individual gestational age in four time periods in hours, 0–24, 24–48, 48–96, and 96 -120 in 1049 preterm infants using 3065 TB samples. Infants <28 weeks GA were excluded since they represented a more diverse population. TB ROR by prematurity groups over all was higher in 32–35 weeks group at 0–12 hours (3.85 umol/L/h) and 25–36 hours (2.81umol/L/h) and decreased at 49–72 hours (0.24umol/L/h) time period as compared to the less mature group. Conclusion Though TB ROR were of similar patterns between prematurity groups (28–31 weeks and 32–35 weeks) it was at higher rate of rise between 13–36 hours and decreasing from 36–72 hours, with a plateau after 72 hours of age. There was a significant difference in the magnitude of TB ROR between prematurity groups at 0–24 hours. Additional research into the clinical care impact on the TB ROR should be conducted to study impact of production and elimination.

Nomogram

10.1093/pch/pxz066.140

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Citations (0)

Development of the Respiratory System

Elsevier eBooks (1986)

Vinod K. Bhutani

10.1016/b978-032303176-9.50006-4

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Citations (0)

A multi-center evaluation of a device for measurement of bilirubin binding capacity in neonates: the effects of gestational age, Intralipid exposure and illness severity

Journal of Perinatology (2019)