Afshin Fayyazi

Hamedan University of Medical Sciences

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Ali Khajeh

Zahedan University of Medical Sciences

Afsaneh Soruri

University of Göttingen

Stefan Schweyer

Starnberg Hospital

Ghasem Miri‐Aliabad

Zahedan University of Medical Sciences

H. J. Radzun

Universitätsmedizin Göttingen

Sven Lahme

Siloah St. Trudpert Klinikum

P. Liske

Siloah St. Trudpert Klinikum

Oliver Lenherr

University of Zurich

Thilo Schlott

University of Göttingen

J. H. Peters

University of Bamberg

Cooperative Institutions

University of Göttingen

Hamedan University of Medical Sciences

Tehran University of Medical Sciences

Universitätsmedizin Göttingen

Shahid Beheshti University of Medical Sciences

Zahedan University of Medical Sciences

Children's Medical Center

Heidelberg University

Iran University of Medical Sciences

University of Tehran

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Efficacy of Melatonin Administration in Reducing Headaches in Children with Migraines without Sleep Disorders.

PubMed (2024)

Afshin Fayyazi Paria Abbasian Seyed Mohammad Sadegh Hosseini Younes Mohammadi Hassan Bazmamoum

Migraine is one of the common diseases of children, which can disrupt their quality of life. Some studies have shown the effect of melatonin in reducing migraine headaches. This study aims to investigate the effect of melatonin administration in reducing headaches in children with migraine without sleep disorders.

Sleep

10.22037/ijcn.v18i3.42197

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Citations (0)

Deformation-induced endothelin B receptor-mediated smooth muscle cell apoptosis is matrix-dependent

Cell Death and Differentiation (2002)

Marco Cattaruzza Marc Moritz Berger Matthias Ochs Afshin Fayyazi L. Füzesi

Pressure overload

10.1038/sj/cdd/4400936

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Citations (2)

EFFICACY OF CONTINUOUS HIGH DOSE MIDAZOLAM INFUSION IN CHILDHOOD REFRACTORY GENERALIZED CONVULSIVE STATUS EPILEPTICUS

Iranian journal of child neurology. (2011)

Afshin Fayyazi Parvaneh Karimzadeh

Objecive Prolonged and uncontrolled refractory status epilepticus (SE) is a life-threatening medical emergency in children (1,2,3). There is no consensus on the optimal therapy for refractory status epilepticus (1). The aim of this study was to develop a new method for treating patients with refractory status epilepticus. Materials & Methods Ten children with refractory status epilepticus in Mofid Hospital, who did not respond to 10 μg/kg per min of intravenous midazolam, had their dose of midazolam increased to 30 μg/kg per min. All children were monitored for the development of side effects. Results Ten children with no response to low-dose midazolam were given a higher dose of midazolam, and 5 (50%) children had a good response. These patients had significantly different response to high-dose midazolam. One patient in the high-dose midazolam group was intubated and required mechanical ventilation. The duration of stay in the hospital and PICU and on mechanical ventilation in patients with no response to low-dose midazolam following with other drugs was longer than in the high-dose midazolam group. No death occurred in high dose midazolam group. Conclusion High-midazolam dose drip infusion is a safe and effective protocol for refractory status epilepticus in children. Keywords: Refractory status epilepticus; midazolam; mortality; childhood

Midazolam

Refractory (planetary science)

Maintenance dose

10.22037/ijcn.v5i3.2401

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Prevalence of Anxiety, Stress and Depressive Symptoms Among Mothers of Children With Epilepsy

Health Scope (2015)

Ali Khajeh Mahboubeh Firouzkoohi Ghasem Miri‐Aliabad Afshin Fayyazi Monireh Miri Bonjar

Background: Epilepsy is a chronic disease that affects the behavior and cognitive performance of children. In many cases, the emotional impacts of epilepsy on the family are neglected. Besides the emotional distress, recurrent seizures may lead to irreversible effects on family members, especially parents. Objectives: This study aimed to evaluate the prevalence of anxiety, stress and depressive disorders among mothers of children with epilepsy. Patients and Methods: This cross-sectional study was conducted on 100 mothers of children with epilepsy. Depression, stress, and anxiety were evaluated using the depression anxiety stress scales (DASS). Data were analyzed by SPSS version 17 and the statistical test of ANOVA. Results: In this study, 14%, 33%, 8% and 20% of the mothers had mild, moderate, severe and very severe levels of anxiety, respectively. As far as the stress is concerned, 8%, 26%, 7% and 11% of the mothers had mild, moderate, severe and very severe levels of stress, respectively. Regarding the depression, 7%, 42%, and 1% of them had mild, moderate and severe level of depression, respectively. Conclusions: The results of the present study showed a significant correlation between motherâs education with stress and depression. However, no significant correlation was observed between the three aforementioned problems and childrenâs personal and familial specifications.

Depression

DASS

Cross-sectional study

10.17795/jhealthscope-18688

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Citations (2)

143 An evaluation of Real-Time-Elastography (RTE): Its detection rate of prostate cancer compared to multiple core biopsies and its dependance of PSA and the volume of the prostate

European Urology Supplements (2013)

Oliver Lenherr Afshin Fayyazi P. Liske Sven Lahme

10.1016/s1569-9056(13)60632-6

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373 Biopsy in flexible ureterorenoscopy: Comparison of biopsy specimen quality using different biopsy forceps

European Urology Supplements (2013)

P. Liske Afshin Fayyazi V. Zimmermanns Sven Lahme

10.1016/s1569-9056(13)60858-1

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Citations (1)

Clinical, biochemical, and histological changes in hepatitis C virus infection-associated cryoglobulinemia.

PubMed (1997)

Afshin Fayyazi Peter Schott Hanna Hartmann Sabine Mihm Peter Middel

The most common extrahepatic manifestation of HCV infection is mixed cryoglobulinemia (MC). 62 unselected patients with chronic HCV infection were prospectively evaluated for the presence of cryoglobulinemia and associated clinical and biochemical parameters. Furthermore, a putative relationship between the HCV genotypes and cryoglobulinemia was tested. Histological features typical for HCV infection were comparatively analyzed in cases with and without cryoglobulinemia. Whether an intrahepatic Th2-response is responsible for the strong antibody production causing cryoglobulinemia was also examined. Cryoglobulins were detected in sera of 30 patients (approximately equal to 48%). Patients with cryoglobulinemia were on the average elder, showed an apparent longer duration of infection, and suffered more frequently from arthralgia, accompanied by a significant increase of total serum IgM concentration and rheumatoid factor activity. The HCV genotype distribution among patients with cryoglobulinemia was not different from that found in patients without cryoglobulinemia. In cases with cryoglobulinemia, an increased activity of chronic hepatitis and a higher grade of liver fibrosis was noted. The prevalence of HCV-typical histological lesions among all patients were: Portal lymphocytic aggregates (40%), bile duct damage (35%), steatosis (47%), and intracellular acidophilic bodies (29%). A significant correlation, however, could not be found between cryoglobulinemia and the presence of HCV-typical histological lesions. An intrahepatic Th2-response causing an increased antibody production could not be observed in cases with cryoglobulinemia.

Cryoglobulins

Hepatitis C

Rheumatoid factor

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Citations (15)

Towards a therapy of malignant melanoma: In-vitro studies with a dendritic-cell x tumor-cell fusion vaccine

Journal of Dermatological Science (1998)

Afsaneh Soruri Thomas M. Rünger Afshin Fayyazi Christine Neumann J. Hinrich Peters

Cell fusion

10.1016/s0923-1811(98)83540-8

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